Detection of amplified or deleted chromosomal regions

Stokke, Trond; Pinkel, Daniel; Gray, Joe W

Title: Detection of amplified or deleted chromosomal regions

Patent · Sun Jan 01 00:00:00 EST 1995

OSTI ID:870192

Stokke, Trond ^[1]; Pinkel, Daniel ^[2]; Gray, Joe W ^[1]

San Francisco, CA
Walnut Creek, CA

The present invention relates to in situ hybridization methods for the identification of new chromosomal abnormalities associated with various diseases. In particular, it provides probes which are specific to a region of amplification in chromosome 20.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

DOE Contract Number:: W-7405-ENG-48

Assignee:: Regents of University of California (Oakland, CA)

Patent Number(s):: US 5472842

OSTI ID:: 870192

Country of Publication:: United States

Language:: English

References (13)

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries Lichter, P.; Cremer, T.; Borden, J. Human Genetics, Vol. 80, Issue 3 https://doi.org/10.1007/BF01790090	journal	November 1988
Complete characterization of a large marker chromosome by reverse and forward chromosome painting Blennow, Elisabeth; Telenius, Håkan; Larsson, Catharina Human Genetics, Vol. 90, Issue 4 https://doi.org/10.1007/BF00220461	journal	December 1992
Analytical strategies for the use of DNA probes Matthews, Jayne A.; Kricka, Larry J. Analytical Biochemistry, Vol. 169, Issue 1, p. 1-25 https://doi.org/10.1016/0003-2697(88)90251-5	journal	February 1988
Translocations between two specific human chromosomes detected by three-color “chromosome painting” Lucas, J. N.; Poggensee, M.; Straume, T. Cytogenetic and Genome Research, Vol. 62, Issue 1 https://doi.org/10.1159/000133434	journal	January 1993
Detection of amplified DNA sequences by reverse chromosome painting using genomic tumor DNA as probe Joos, Stefan; Scherthan, Harry; Speicher, MichaelR. Human Genetics, Vol. 90, Issue 6 https://doi.org/10.1007/BF00202475	journal	February 1993
Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4. Pinkel, D.; Landegent, J.; Collins, C. Proceedings of the National Academy of Sciences, Vol. 85, Issue 23 https://doi.org/10.1073/pnas.85.23.9138	journal	December 1988
Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Kallioniemi, A.; Kallioniemi, O. P.; Piper, J. Proceedings of the National Academy of Sciences, Vol. 91, Issue 6 https://doi.org/10.1073/pnas.91.6.2156	journal	March 1994
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors Kallioniemi, A.; Kallioniemi, O.; Sudar, D. Science, Vol. 258, Issue 5083 https://doi.org/10.1126/science.1359641	journal	October 1992
High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones Lichter, P.; Tang, C.; Call, K. Science, Vol. 247, Issue 4938 https://doi.org/10.1126/science.2294592	journal	January 1990
In situ hybridisation with fluoresceinated DNA Wiegant, Joop; Ried, Thomas; Nederlof, Petra M. Nucleic Acids Research, Vol. 19, Issue 12 https://doi.org/10.1093/nar/19.12.3237	journal	January 1991
Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma Bergerheim, Ulf S. R.; Kunimi, Kazuto; Collins, V. Peter Genes, Chromosomes and Cancer, Vol. 3, Issue 3 https://doi.org/10.1002/gcc.2870030308	journal	May 1991
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization. Kallioniemi, O. P.; Kallioniemi, A.; Kurisu, W. Proceedings of the National Academy of Sciences, Vol. 89, Issue 12 https://doi.org/10.1073/pnas.89.12.5321	journal	June 1992
Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes Cremer, T.; Lichter, P.; Borden, J. Human Genetics, Vol. 80, Issue 3 https://doi.org/10.1007/BF01790091	journal	November 1988

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Title: Detection of amplified or deleted chromosomal regions

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