Laser excited confocal microscope fluorescence scanner and method

Mathies, Richard A; Peck, Konan

Title: Laser excited confocal microscope fluorescence scanner and method

Patent · Wed Jan 01 00:00:00 EST 1992

OSTI ID:868178

Mathies, Richard A ^[1]; Peck, Konan ^[1]

Contra Costa, CA

A fluorescent scanner for scanning the fluorescence from a fluorescence labeled separated sample on a sample carrier including a confocal microscope for illuminating a predetermined volume of the sample carrier and/or receiving and processing fluorescence emissions from said volume to provide a display of the separated sample.

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Research Organization:: Univ. of California (United States)

DOE Contract Number:: FG03-88ER60706

Assignee:: Regents of University of California (Oakland, CA)

Patent Number(s):: US 5091652

OSTI ID:: 868178

Country of Publication:: United States

Language:: English

References (7)

Non-radioactive automated sequencing of oligonucleotides by chemical degradation Ansorge, W.; Rosenthal, A.; Sproat, B. Nucleic Acids Research, Vol. 16, Issue 5 https://doi.org/10.1093/nar/16.5.2203	journal	January 1988
Fluorescence detection in automated DNA sequence analysis Smith, Lloyd M.; Sanders, Jane Z.; Kaiser, Robert J. Nature, Vol. 321, Issue 6071, p. 674-679 https://doi.org/10.1038/321674a0	journal	June 1986
Optimization of high-sensitivity fluorescence detection Mathies, Richard A.; Peck, Konan.; Stryer, Lubert. Analytical Chemistry, Vol. 62, Issue 17, p. 1786-1791 https://doi.org/10.1021/ac00216a012	journal	September 1990
Detection of single molecules of phycoerythrin in hydrodynamically focused flows by laser-induced fluorescence Nguyen, Dinh Cong; Keller, Richard A.; Jett, James H. Analytical Chemistry, Vol. 59, Issue 17 https://doi.org/10.1021/ac00144a032	journal	September 1987
Single-molecule fluorescence detection: autocorrelation criterion and experimental realization with phycoerythrin. Peck, K.; Stryer, L.; Glazer, A. N. Proceedings of the National Academy of Sciences, Vol. 86, Issue 11 https://doi.org/10.1073/pnas.86.11.4087	journal	June 1989
DNA sequencing with chain-terminating inhibitors Sanger, F.; Nicklen, S.; Coulson, A. R. Proceedings of the National Academy of Sciences, Vol. 74, Issue 12 https://doi.org/10.1073/pnas.74.12.5463	journal	December 1977
A stable double-stranded DNA-ethidium homodimer complex: application to picogram fluorescence detection of DNA in agarose gels. Glazer, A. N.; Peck, K.; Mathies, R. A. Proceedings of the National Academy of Sciences, Vol. 87, Issue 10 https://doi.org/10.1073/pnas.87.10.3851	journal	May 1990

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Related Subjects

laser
excited
confocal
microscope
fluorescence
scanner
method
fluorescent
scanning
labeled
separated
sample
carrier
including
illuminating
predetermined
volume
receiving
processing
emissions
provide
display
confocal microscope
predetermined volume
fluorescence emission
fluorescence emissions
fluorescence scanner
/250/204/

Title: Laser excited confocal microscope fluorescence scanner and method

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References (7)

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