Fundamental limits of positron emission mammography

Moses, William W; Qi, Jinyi

Title: Fundamental limits of positron emission mammography

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Abstract

We explore the causes of performance limitation in positron emission mammography cameras. We compare two basic camera geometries containing the same volume of 511 keV photon detectors, one with a parallel plane geometry and another with a rectangular geometry. We find that both geometries have similar performance for the phantom imaged (in Monte Carlo simulation), even though the solid angle coverage of the rectangular camera is about 50 percent higher than the parallel plane camera. The reconstruction algorithm used significantly affects the resulting image; iterative methods significantly outperform the commonly used focal plane tomography. Finally, the characteristics of the tumor itself, specifically the absolute amount of radiotracer taken up by the tumor, will significantly affect the imaging performance.

Authors:: Moses, William W; Qi, Jinyi

Publication Date:: Fri Jun 01 00:00:00 EDT 2001

Research Org.:: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Sponsoring Org.:: USDOE Director, Office of Science. Office of Biological and Environmental Research. Medical Sciences Division; National Institutes of Health (US)

OSTI Identifier:: 835336

Report Number(s):: LBNL-48131
R&D Project: 445001; TRN: US0500026

DOE Contract Number:: AC03-76SF00098

Resource Type:: Journal Article

Journal Name:: Nuclear Instruments and Methods A

Additional Journal Information:: Journal Volume: 497; Journal Issue: 1; Other Information: Submitted to Nuclear Instruments and Methods A, Volume 497, No.1; Journal Publication Date: 01/21/2003; PBD: 1 Jun 2001

Country of Publication:: United States

Language:: English

Subject:: 72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS; 62 RADIOLOGY AND NUCLEAR MEDICINE; ALGORITHMS; CAMERAS; GEOMETRY; ITERATIVE METHODS; NEOPLASMS; PERFORMANCE; PHANTOMS; PHOTONS; POSITRONS; SIMULATION; TOMOGRAPHY; PET BREAST CANCER POSITRON EMISSION MAMMOGRAPHY

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                    Moses, William W, and Qi, Jinyi. Fundamental limits of positron emission mammography.  United States: N. p., 2001. 
        Web.

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                    Moses, William W, & Qi, Jinyi. Fundamental limits of positron emission mammography.  United States.

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                    Moses, William W, and Qi, Jinyi. 2001.  
        "Fundamental limits of positron emission mammography".  United States.  https://www.osti.gov/servlets/purl/835336.

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@article{osti_835336,

  title        = {Fundamental limits of positron emission mammography},

  author       = {Moses, William W and Qi, Jinyi},

  abstractNote = {We explore the causes of performance limitation in positron emission mammography cameras. We compare two basic camera geometries containing the same volume of 511 keV photon detectors, one with a parallel plane geometry and another with a rectangular geometry. We find that both geometries have similar performance for the phantom imaged (in Monte Carlo simulation), even though the solid angle coverage of the rectangular camera is about 50 percent higher than the parallel plane camera. The reconstruction algorithm used significantly affects the resulting image; iterative methods significantly outperform the commonly used focal plane tomography. Finally, the characteristics of the tumor itself, specifically the absolute amount of radiotracer taken up by the tumor, will significantly affect the imaging performance.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/835336},
  journal      = {Nuclear Instruments and Methods A},
number       = 1,

  volume       = 497,

  place        = {United States},

  year         = {Fri Jun 01 00:00:00 EDT 2001},

  month        = {Fri Jun 01 00:00:00 EDT 2001}

}

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