Intraoral fiber optic-based diagnostic for periodontal disease
The purpose of this initial study was to begin development of a new, objective diagnostic instrument that will allow simultaneous quantitation of multiple proteases within a single periodontal pocket using a chemical fiber optic sensor. This approach could potentially be adapted to use specific antibodies and chemiluminescence to detect and quantitate virtually any compound and compare concentrations of different compounds within the same periodontal pocket. The device could also be used to assay secretions in salivary ducts or from a variety of wounds. The applicability is, therefore, not solely limited to dentistry and the device would be important both for clinical diagnostics and as a research tool.
- Research Organization:
- Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
- Sponsoring Organization:
- USDOE Office of Defense Programs (DP) (US)
- DOE Contract Number:
- W-7405-ENG-48
- OSTI ID:
- 756791
- Report Number(s):
- UCRL-JC-137259; EW4090100; EW4090100; TRN: AH200020%%41
- Resource Relation:
- Conference: International Symposium on Biomedical Optics, San Jose, CA (US), 01/22/2000; Other Information: PBD: 21 Jan 2000
- Country of Publication:
- United States
- Language:
- English
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