Monitoring genetic damage to ecosystems from hazardous waste

Conference · Sun Mar 01 00:00:00 EST 1992

OSTI ID:7049872

Anderson, S L

Applications of ecological toxicity testing to hazardous waste management have increased dramatically over the last few years, resulting in a greater awareness of the need for improved biomonitoring techniques. Our laboratory is developing advanced techniques to assess the genotoxic effects of environmental contamination on ecosystems. We have developed a novel mutagenesis assay using the nematode Caenorhabditis elegans, which is potentially applicable for multimedia studies in soil, sediment, and water. In addition, we are conducting validation studies of a previously developed anaphase aberration test that utilizes sea urchin embryos. Other related efforts include field validation studies of the new tests, evaluation of their potential ecological relevance, and analysis of their sensitivity relative to that of existing toxicity tests that assess only lethal effects, rather than genetic damage.

• Research Organization: Lawrence Berkeley Lab., CA (United States)
• Sponsoring Organization: NIEHS; National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States)
• DOE Contract Number: AC03-76SF00098
• OSTI ID: 7049872
• Report Number(s): LBL-31983; CONF-9204172-1; ON: DE92016922; CNN: NIH P42ES04705-03; 0-137-1220-0
• Resource Relation: Conference: Pacific Basin conference on hazardous waste, Bangkok (Thailand), 6-10 Apr 1992
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
54 ENVIRONMENTAL SCIENCES
ENVIRONMENT
MONITORING
HAZARDOUS MATERIALS
GENETIC EFFECTS
TOXICITY
TESTING
VALIDATION
BIOLOGY
DNA
ECOLOGY
NEMATODES
RISK ASSESSMENT
WASTE MANAGEMENT
ASCHELMINTHES
BIOLOGICAL EFFECTS
HELMINTHS
MANAGEMENT
MATERIALS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
560300* - Chemicals Metabolism & Toxicology
550200 - Biochemistry
540220 - Environment
Terrestrial- Chemicals Monitoring & Transport- (1990-)