(Study of the mechanism of carcinogenesis by carcinogens which are negative in the Ames test). Comprehensive report of overall activities for the past three years. [Uv radiation; hormone metabolism]

Technical Report · Sun Jan 01 00:00:00 EST 1978

DOI:https://doi.org/10.2172/6691994· OSTI ID:6691994

Borek, E

Progress is reported on the following: DNA methylation and sensitivity of Escherichia coli to uv radiation; hormonal control of tRNA methyltransferases and tRNA structure; development of tRNA-dependent, in vitro protein synthesizing system from Ehrlich ascites cells; and effects of the carcinogens ethionine and carbon tetrachlorides on balance of estrogens and progestins in immature chicks. (HLW)

• Research Organization: University of Colorado Medical Center, Denver, CO (USA).
• Sponsoring Organization: USDOE
• DOE Contract Number: EY-76-S-02-2066
• OSTI ID: 6691994
• Report Number(s): COO-2066-31
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
CARBON TETRACHLORIDE
BIOLOGICAL EFFECTS
DNA
METHYLATION
ESCHERICHIA COLI
RADIOSENSITIVITY
ESTROGENS
METABOLISM
ETHIONINE
PROGESTERONE
TRANSFER RNA
MOLECULAR STRUCTURE
ASCITES TUMOR CELLS
BIOSYNTHESIS
CHICKENS
HORMONES
MUTAGENS
PROTEINS
SCREENING
TRANSFERASES
ULTRAVIOLET RADIATION
AMINO ACIDS
ANIMAL CELLS
ANIMALS
BACTERIA
BIRDS
CARBOXYLIC ACIDS
CHEMICAL REACTIONS
CHLORINATED ALIPHATIC HYDROCARBONS
ELECTROMAGNETIC RADIATION
ENZYMES
FOWL
HALOGENATED ALIPHATIC HYDROCARBONS
KETONES
LIPOTROPIC FACTORS
MICROORGANISMS
NUCLEIC ACIDS
ORGANIC ACIDS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PREGNANES
RADIATIONS
RNA
STEROID HORMONES
STEROIDS
SYNTHESIS
TUMOR CELLS
VERTEBRATES
560131* - Radiation Effects on Microorganisms- Basic Studies- (-1987)
550500 - Metabolism
550200 - Biochemistry