[Studies of the repair of radiation-induced genetic damage in Drosophila]. Final progress report

Technical Report · Sun Nov 01 00:00:00 EST 1998

DOI:https://doi.org/10.2172/666243· OSTI ID:666243

Hawley, R. S.

This research focuses on the structure of the mei-41 gene and elucidation of the role the mei-41 gene product plays in both recombination and repair. Genetic and molecular studies are continuing on the mus308 locus and the mus312 and mei-9 genes. The author views mus312 as a very likely candidate for a gene required for both chromosome pairing/synopsis and for double strand break repair. A thorough genetic study has been initiated of this locus and of the cytology of the meiotic and mitotic defects of mutations at this locus.

• Research Organization: Univ. of California, Dept. of Genetics, Davis, CA (United States)
• Sponsoring Organization: USDOE Office of Energy Research, Washington, DC (United States)
• DOE Contract Number: FG03-87ER60538
• OSTI ID: 666243
• Report Number(s): DOE/ER/60538-T9; ON: DE99000069; TRN: AHC29819%%403
• Resource Relation: Other Information: PBD: [1998]
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
PROGRESS REPORT
MOLECULAR STRUCTURE
GENES
GENE RECOMBINATION
DNA REPAIR
CHROMOSOMES
STRAND BREAKS
GENETICS