Proton-induces and x-ray induced fluorescence analysis of scoliotic tissue
Adolescent idiopathic scoliosis is characterized by a curvature or assymetry of the spine which may become progressively more severe, with clinical symptoms appearing just prior to, or during, puberty. The incidence for scoliosis in the age group from 12 to 14 years of age has been reported as high as 8 to 10%, with more than 80% of the cases occurring in females. Although pathologic changes exist in muscles from both sides of the spinal curvature, and no statistically significant side differences have been reported, morphologic changes suggest that the concanve side is the most affected. This paper reports our preliminary data on the elemental composition of individual muscle fibers derived from convex, concave and gluteal scoliotic muscle, and erythrocytes from scoliotic and normal patients, analyzed by proton induced x-ray emission (PIXE) and x-ray fluorescence spectroscopy (XRF). A new type of specimen holder was designed for this study which offers low x-ray background, minimal absorption and maintenance of a moist environment around the specimen.
- Research Organization:
- Brookhaven National Lab., Upton, NY (USA)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC02-76CH00016
- OSTI ID:
- 5372063
- Report Number(s):
- BNL-27325; CONF-800801-6
- Resource Relation:
- Conference: Annual meeting of the Electron Microscopy Society of America and 15. Microbeam Analysis Society Conference, San Francisco, CA, USA, 4 Aug 1980
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ERYTHROCYTES
CHEMICAL COMPOSITION
MUSCLES
WOMEN
HEREDITARY DISEASES
MALFORMATIONS
MORPHOLOGICAL CHANGES
SELENIUM
TRACE AMOUNTS
VERTEBRAE
X-RAY SPECTROSCOPY
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
DISEASES
ELEMENTS
FEMALES
MAMMALS
MAN
MATERIALS
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
SEMIMETALS
SKELETON
SPECTROSCOPY
VERTEBRATES
550900* - Pathology