THE RESPONSE OF DISSEMINATED RETICULUM CELL SARCOMA TO THE INTRAVENOUS INJECTION OF COLLOIDAL RADIOACTIVE GOLD
Case histories of two patients treated with colloidal radiogold for diffuse reticulum cell sarcoma are presented. Further analysis of the method is suggested by the unusually long survival time of one of the patients. It was concluded that, although external radiotherapy remains the treatment of choice in localized reticulum cell sarcoma, intravenous colloidal radiogold may be a useful agent in lymphosarcomas with diffuse minute neoplastic liver and spleen involvements. Intravenous colloidal radiogold can produce bone marrow depression and thrombocytopenia which can lead to death. This factor tends to argue against therapeutic use of the agent. It is suggested that no more than 50 mC Au/sup 198/ intravenously should be used for treatment of this disease. (R.M.G.)
- Research Organization:
- Univ. of Rochester Medical Center, NY (United States); Univ. of Oklahoma Medical Center, Oklahoma City, OK (United States)
- Sponsoring Organization:
- Sponsor not identified
- NSA Number:
- NSA-18-003669
- OSTI ID:
- 4878068
- Report Number(s):
- CONF-164-7
- Resource Relation:
- Conference: Society of Nuclear Medicine 10th Annual Meeting, Montreal, Quebec (Canada), 26-29 Jun 1963
- Country of Publication:
- United States
- Language:
- English
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