Multiheteromacrocycles that complex metal ions. Second progress report, 1 May 1975--30 April 1976
Objective is to develop cyclic and polycyclic host organic compounds to complex and lipophilize metal ions. Macrorings were synthesized: (OCH$sub 2$ CH$sub 2$ O CH$sub 2$COCH$sub 2$ COCH$sub 2$$)$$sub 2$ and (OCH$sub 2$ CH$sub 2$ O CH$sub 2$ COCH$sub 2$ COCH$sub 2$$)$$sub 3$. The smaller ring complexes divalent metals 10$sup 1+9$ times better than the open-chain model CH$sub 3$ O CH$sub 2$ CO CH$sub 2$ COCH$sub 2$ O CH$sub 3$, and the order in which metal ions are complexed is Cu$sup 2+$, UO$sub 2$$sup 2+$ greater than Ni$sup 2+$ greater than Fe$sup 2+$, Co$sup 2+$, Zn$sup 2+$, Cd$sup 2+$ greater than Mn$sup 2+$. The UO$sub 2$$sup 2+$ and Cu$sup 2+$ complexes were isolated and characterized. The larger ring complexes trivalent metals 10/sup 0.9-1.7/ times better than the open- chain model compound, and the order is La$sup 3+$, Ce$sup 3+$ greater than Cr$sup 3+$. Five other macrocycles were also synthesized, and their binding constants with Na, K, NH$sub 4$, and Cs picrates were measured. Six compounds containing one macroring and two inward-pointing ArOH or ArOCH$sub 3$ groups were also prepared and tested for binding of Li, Na, K, Rb, and NH$sub 4$ picrates. Racemic compounds containing two binaphthyls and its sulfur analog were prepared. Cage-shaped multiheteromacrocycles containing ten O ligand sites or four S and six O ligand sites were prepared and the binding capability of the first compound for picrates studied. Two ring systems with phosphonate ester groups were also prepared. (DLC)
- Research Organization:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- DOE Contract Number:
- AT(04-3)-34
- NSA Number:
- NSA-33-019685
- OSTI ID:
- 4086876
- Report Number(s):
- UCLA-34P218X2
- Resource Relation:
- Other Information: Orig. Receipt Date: 30-JUN-76
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
Organic
& Physical Chemistry
400300* -Chemistry-Organic Chemistry
*CADMIUM COMPLEXES- STABILITY
*CERIUM COMPLEXES- STABILITY
*HETEROCYCLIC COMPOUNDS- CHEMICAL PREPARATION
*LANTHANUM COMPLEXES- STABILITY
*ORGANIC COMPOUNDS- CHEMICAL PREPARATION
*URANYL COMPLEXES- STABILITY
CHROMIUM COMPLEXES
COBALT COMPLEXES
COMPLEXES
COPPER COMPLEXES
IRON COMPLEXES
MANGANESE COMPLEXES
NICKEL COMPLEXES
ZINC COMPLEXES