The Early ANTP Gene Repertoire: Insights from the Placozoan Genome
- Stiftung Tieraerztliche Hochschule Hannover (Germany); Yale Univ., New Haven, CT (United States)
- Stiftung Tieraerztliche Hochschule Hannover (Germany)
- Univ. of California, Berkeley, CA (United States)
- USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States); Univ. of California, Berkeley, CA (United States)
- Yale Univ., New Haven, CT (United States)
The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals. Whole genome sequences have recently filled in some crucial gaps for the basal metazoan phyla Cnidaria and Porifera. Here we analyze the complete genome of Trichoplax adhaerens, representing the basal metazoan phylum Placozoa, for its set of ANTP class genes. The Trichoplax genome encodes representatives of Hox/ParaHox-like, NKL, and extended Hox genes. This repertoire possibly mirrors the condition of a hypothetical cnidarian-bilaterian ancestor. The evolution of the cnidarian and bilaterian ANTP gene repertoires can be deduced by a limited number of cis-duplications of NKL and “extended Hox” genes and the presence of a single ancestral “ProtoHox” gene.
- Research Organization:
- USDOE Joint Genome Institute (JGI), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC), Biological and Environmental Research (BER); National Science Foundation (NSF); Human Frontier Science Program; National Institutes of Health (NIH)
- Grant/Contract Number:
- AC02-05CH11231; RR19895; RGP 0221
- OSTI ID:
- 1904079
- Journal Information:
- PLoS ONE, Vol. 3, Issue 8; ISSN 1932-6203
- Publisher:
- Public Library of ScienceCopyright Statement
- Country of Publication:
- United States
- Language:
- English
Similar Records
Early evolution of the LIM homeobox gene family
The Trichoplax Genome and the Nature of Placozoans