Determination of ligninases activities by nano-structure initiator mass spectrometry

Northen, Trent R.; Deng, Kai

Title: Determination of ligninases activities by nano-structure initiator mass spectrometry

Patent · Tue Nov 03 00:00:00 EST 2020

OSTI ID:1771579

Northen, Trent R.; Deng, Kai

A method for rapid, high throughput screening of the activities of enzymes, especially ligninases and its enzyme cocktails, using nanostructure initiator mass spectrometry (NIMS) surfaces, substrates and methodology.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

Assignee:: The Regents of the University of California (Oakland, CA); National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)

Patent Number(s):: 10,822,634

Application Number:: 15/499,769

OSTI ID:: 1771579

Resource Relation:: Patent File Date: 04/27/2017

Country of Publication:: United States

Language:: English

References (15)

Rapid characterization of the activities of lignin-modifying enzymes based on nanostructure-initiator mass spectrometry (NIMS) Deng, Kai; Zeng, Jijiao; Cheng, Gang Biotechnology for Biofuels, Vol. 11, Issue 1 https://doi.org/10.1186/s13068-018-1261-2	journal	September 2018
Mass spectrometry methods and apparatus Greving, Matthew; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9082600 US Patent Document 9,082,600	patent	July 2015
Rapid Discovery and Screening of Enzyme Activity Using Mass Spectrometry Northen, Trent R.; Deng, Kai; De Rond, Tristan P. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20150330992 US Patent Application 14/651546; 20150330992	patent-application	November 2015
Methods, apparatus, and compositions for mass spectrometry Greving, Matthew; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9460904 US Patent Document 9,460,904	patent	October 2016
Metabolic Flux Measurement, Imaging and Microscopy Bowen, Benjamin P.; Louie, Katherine B.; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140329274 US Patent Application 14/343334; 20140329274	patent-application	November 2014
Colloid-based multiplexed screening for plant biomass-degrading glycoside hydrolase activities in microbial communities Reindl, W.; Deng, K.; Gladden, J. M. Energy & Environmental Science, Vol. 4, Issue 8 https://doi.org/10.1039/c1ee01112j	journal	January 2011
Nanostructure-initiator mass spectrometry biometrics Leclerc, Marion; Bowen, Benjamin P.; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9125596 US Patent Document 9,125,596	patent	September 2015
Hydrogenolysis of β-O-4 lignin model dimers by a ruthenium-xantphos catalyst Wu, Adam; Patrick, Brian O.; Chung, Enoch Dalton Transactions, Vol. 41, Issue 36 https://doi.org/10.1039/c2dt31065a	journal	January 2012
Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis Woo, Hin-Koon; Northen, Trent R.; Yanes, Oscar Nature Protocols, Vol. 3, Issue 8 https://doi.org/10.1038/nprot.2008.110	journal	July 2008
Nanostructure-Initiator Mass Spectrometry Northen, Trent; Siuzdak, Gary; Nordstrom, Anders https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20080128608 US Patent Document 11/852863; 20080128608	patent-application	June 2008
A nanostructure-initiator mass spectrometry-based enzyme activity assay Northen, T. R.; Lee, J.-C.; Hoang, L. Proceedings of the National Academy of Sciences, Vol. 105, Issue 10, p. 3678-3683 https://doi.org/10.1073/pnas.0712332105	journal	March 2008
Clathrate nanostructures for mass spectrometry Northen, Trent R.; Yanes, Oscar; Northen, Michael T. Nature, Vol. 449, Issue 7165 https://doi.org/10.1038/nature06195	journal	October 2007
Multiplexed Screening of Enzyme Activities Using Nanostructure-initiator Mass Spectrometry Northen, Trent R.; Reindl, Wolfgang E.; Deng, Kai https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20120225797 US Patent Application 13/363695; 20120225797	patent-application	September 2012
Nanostructure-initiator Mass Spectrometry Biometrics Leclerc, Marion; Bowen, Benjamin; Northen, Trent https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140247115 US Patent Application 13/631687; 20140247115	patent-application	September 2014
Simple method for synthesizing phenolicβ-O-4 dilignols Kawai, Shingo; Okita, Kyoko; Sugishita, Kazuhiro Journal of Wood Science, Vol. 45, Issue 5 https://doi.org/10.1007/BF01177919	journal	October 1999

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