Detection of analytes using porous mass spectrometry surface

Gao, Jian; Northen, Trent R.

Title: Detection of analytes using porous mass spectrometry surface

Patent · Tue Mar 24 00:00:00 EDT 2020

OSTI ID:1637810

Gao, Jian; Northen, Trent R.

The disclosure herein includes compositions and methods for ionizing targets and methods for making the compositions. In some embodiments, the compositions can include a porous substrate that has been etched for a desired average pore size, a desired porosity, or both for detection of one or more targets of interest. Also disclosed herein are methods for using the composition to ionize targets.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

DOE Contract Number:: AC02-05CH11231; SC0014079

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 10,600,629

Application Number:: 15/899,923

OSTI ID:: 1637810

Resource Relation:: Patent File Date: 02/20/2018

Country of Publication:: United States

Language:: English

References (7)

Methods and devices for improving atom probe detector performance Kelly, Thomas F.; Lenz, Daniel; Wiener, Scott A. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8575544 US Patent Document 8,575,544	patent	November 2013
Microstructure and Microdomain Microarrays, Methods of Making Same and Uses Thereof Greving, Matthew; Woodbury, Neal; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20100056392 US Patent Application 11/917406; 20100056392	patent-application	March 2010
Nanostructure-initiator mass spectrometry biometrics Leclerc, Marion; Bowen, Benjamin P.; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9125596 US Patent Document 9,125,596	patent	September 2015
Nanostructure-Initiator Mass Spectrometry Northen, Trent; Siuzdak, Gary; Nordstrom, Anders https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20080128608 US Patent Document 11/852863; 20080128608	patent-application	June 2008
Mass spectrometry analysis of microorganisms in samples Cooks, Robert Graham; Hamid, Ahmed Mohamed; Jarmusch, Alan Keith https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8704167 US Patent Document 8,704,167	patent	April 2014
Fabrication of Mass Spectrometry Surface Gao, Jian; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20180254177 US Patent Application 15/759192; 20180254177 A1	patent-application	September 2018
Detection of Analytes Using Porous Mass Spectrometry Surface Gao, Jian; Northen, Trent R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20180269052 US Patent Application 15/899923; 20180269052	patent-application	September 2018

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