Method for detecting organophosphorus compounds and illicit drugs

Ewing, Robert G.; Valenzuela, Blandina R.; Atkinson, David A.

Title: Method for detecting organophosphorus compounds and illicit drugs

Patent · Tue Nov 06 00:00:00 EST 2018

OSTI ID:1492824

Ewing, Robert G.; Valenzuela, Blandina R.; Atkinson, David A.

A method is disclosed for detecting organophosphorus compounds and illicit drugs using an ion detector. A vapor sample containing at least one analyte and at least one dopant is ionized. A proton-bound adduct ion is formed between the analyte and the dopant in a reaction region defined between the ionization source and the ion detector.

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Research Organization:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC0576RL01830

Assignee:: Battelle Memorial Institute (Richland, WA)

Patent Number(s):: 10,119,937

Application Number:: 15/211,752

OSTI ID:: 1492824

Resource Relation:: Patent File Date: 2016 Jul 15

Country of Publication:: United States

Language:: English

References (10)

Proton-bound cluster ions in ion mobility spectrometry Ewing, Robert G.; Eiceman, Gary A.; Stone, J. A. International Journal of Mass Spectrometry, Vol. 193, Issue 1 https://doi.org/10.1016/S1387-3806(99)00141-4	journal	October 1999
Reliability of ion mobility spectrometry for qualitative analysis of complex, multicomponent illicit drug samples Verkouteren, Jennifer R.; Staymates, Jessica L. Forensic Science International, Vol. 206, Issue 1-3 https://doi.org/10.1016/j.forsciint.2010.08.005	journal	March 2011
Method for selective detection of explosives in mass spectrometer or ion mobility spectrometer at parts-per-quadrillion level Ewing, Robert G.; Atkinson, David A.; Clowers, Brian H. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9123520 US Patent Document 9,123,520	patent	September 2015
Ion mobility spectrometric analysis of vaporous chemical warfare agents by the instrument with corona discharge ionization ammonia dopant ambient temperature operation Satoh, Takafumi; Kishi, Shintaro; Nagashima, Hisayuki Analytica Chimica Acta, Vol. 865, p. 39-52 https://doi.org/10.1016/j.aca.2015.02.004	journal	March 2015
System and Process for Selective Detection of Vapor-Phase Analytes Ewing, Robert G.; Atkinson, David A.; Clovers, Brian H. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130260478 US Patent Application 13/437718; 20130260478	patent-application	October 2013
Tandem differential mobility spectrometers and mass spectrometer for enhanced analysis Miller, Raanan A.; Nazarov, Erkinjon G.; Vouros, Paul https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20080149824 US Patent Application 11/823666; 20080149824	patent-application	June 2008
Ammonia monitor based on ion mobility spectrometry with selective dopant chemistry Bacon, Jr., Allan T. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5234838 US Patent Document 5,234,838	patent	August 1993
Dopants and gas modifiers in ion mobility spectrometry Waraksa, Emilia; Perycz, Urszula; Namieśnik, Jacek TrAC Trends in Analytical Chemistry, Vol. 82, p. 237-249 https://doi.org/10.1016/j.trac.2016.06.009	journal	September 2016
Detection of designer drugs in human hair by ion mobility spectrometry (IMS) Keller, Thomas; Miki, Akihiro; Regenscheit, Priska Forensic Science International, Vol. 94, Issue 1-2, p. 55-63 https://doi.org/10.1016/S0379-0738(98)00051-6	journal	June 1998
Ion mobility spectrometers with doped gases Puton, Jarosław; Nousiainen, Marjaana; Sillanpää, Mika Talanta, Vol. 76, Issue 5, p. 978-987 https://doi.org/10.1016/j.talanta.2008.05.031	journal	September 2008

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