Chemoresponsive Nanofluidic Pump That Turns Off in the Presence of Lead Ion

Wu, Xiaojian; Experton, Juliette; Xu, Weihuang; Martin, Charles R.

doi:10.1021/acs.analchem.8b01623

Title: Chemoresponsive Nanofluidic Pump That Turns Off in the Presence of Lead Ion

Journal Article · Thu May 24 00:00:00 EDT 2018 · Analytical Chemistry

DOI:https://doi.org/10.1021/acs.analchem.8b01623· OSTI ID:1470663

Wu, Xiaojian ^[1]; Experton, Juliette ^[1]; Xu, Weihuang ^[1];

^[1]

Univ. of Florida, Gainesville, FL (United States). Dept. of Chemistry

There are many applications that require the integration of a pump and a chemical sensor so that the solution being pumped can be analyzed in real time for a specific chemical species and the flow adjusted according to the measured concentration of that species. In this paper, we describe an alternative strategy: a chemoresponsive pump where a single device acts as both the sensor and pump simultaneously. We demonstrate this concept with a nanofluidic Pb²⁺-responsive pump that uses electroosmotic flow as the pumping technology, and a Pb²⁺-binding ionophore that allows the device to selectively respond to Pb²⁺. The pump yields high flow rates at low Pb²⁺ concentrations (<1 μM), but flow rate decreases with concentrations above this threshold and ultimately goes to zero at concentrations above 100 μM.

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Research Organization:: Energy Frontier Research Centers (EFRC) (United States). Nanostructures for Electrical Energy Storage (NEES)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0001160

OSTI ID:: 1470663

Journal Information:: Analytical Chemistry, Vol. 90, Issue 12; Related Information: NEES partners with University of Maryland (lead); University of California, Irvine; University of Florida; Los Alamos National Laboratory; Sandia National Laboratories; Yale University; ISSN 0003-2700

Publisher:: American Chemical Society (ACS)Copyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 18 works

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References (35)

Application of ultrasonic sensors in the process industry Hauptmann, Peter; Hoppe, Niels; Püttmer, Alf Measurement Science and Technology, Vol. 13, Issue 8 https://doi.org/10.1088/0957-0233/13/8/201	journal	July 2002
Micromachined flow sensors—a review Nguyen, N. T. Flow Measurement and Instrumentation, Vol. 8, Issue 1 https://doi.org/10.1016/S0955-5986(97)00019-8	journal	March 1997
Electrode Systems for Continuous Monitoring in Cardiovascular Surgery Clark, Leland C.; Lyons, Champ Annals of the New York Academy of Sciences, Vol. 102, Issue 1 https://doi.org/10.1111/j.1749-6632.1962.tb13623.x	journal	October 1962
Glucose Biosensors: 40 Years of Advances and Challenges Wang, Joseph Electroanalysis, Vol. 13, Issue 12 https://doi.org/10.1002/1521-4109(200108)13:12<983::AID-ELAN983>3.0.CO;2-#	journal	August 2001
Chemistry pumps: a review of chemically powered micropumps Zhou, Chao; Zhang, Hua; Li, Zeheng Lab on a Chip, Vol. 16, Issue 10 https://doi.org/10.1039/C6LC00032K	journal	January 2016
Autonomous Microfluidic Control by Chemically Actuated Micropumps and Its Application to Chemical Analyses Takashima, Atsushi; Kojima, Kenichi; Suzuki, Hiroaki Analytical Chemistry, Vol. 82, Issue 16 https://doi.org/10.1021/ac1009657	journal	August 2010
Self-powered enzyme micropumps Sengupta, Samudra; Patra, Debabrata; Ortiz-Rivera, Isamar Nature Chemistry, Vol. 6, Issue 5 https://doi.org/10.1038/nchem.1895	journal	March 2014
A Biomimetic, Self-Pumping Membrane Jun, In-Kook; Hess, Henry Advanced Materials, Vol. 22, Issue 43 https://doi.org/10.1002/adma.201001694	journal	September 2010
Electroosmotic pumps and their applications in microfluidic systems Wang, Xiayan; Cheng, Chang; Wang, Shili Microfluidics and Nanofluidics, Vol. 6, Issue 2 https://doi.org/10.1007/s10404-008-0399-9	journal	January 2009
An Alternating Current Electroosmotic Pump Based on Conical Nanopore Membranes Wu, Xiaojian; Ramiah Rajasekaran, Pradeep; Martin, Charles R. ACS Nano, Vol. 10, Issue 4 https://doi.org/10.1021/acsnano.6b00939	journal	April 2016
Ion-Current Rectification in Nanopores and Nanotubes with Broken Symmetry Siwy, Z. S. Advanced Functional Materials, Vol. 16, Issue 6 https://doi.org/10.1002/adfm.200500471	journal	April 2006
Diode-like single-ion track membrane prepared by electro-stopping Apel, P. Yu.; Korchev, Yu. E.; Siwy, Z. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 184, Issue 3, p. 337-346 https://doi.org/10.1016/S0168-583X(01)00722-4	journal	November 2001
Kinetic studies of complexation of divalent strontium, barium, lead and mercury cations by aqueous 15-crown-5 and 18-crown-6 Rodriguez, Licesio J.; Liesegang, Gerard W.; Farrow, Michael M. The Journal of Physical Chemistry, Vol. 82, Issue 6 https://doi.org/10.1021/j100495a005	journal	March 1978
Lead-Selective Membrane Electrode Based on Dibenzopyrydino-18-Crown-6 Tavakkoli, Nahid; Shamsipur, Mojtaba Analytical Letters, Vol. 29, Issue 13 https://doi.org/10.1080/00032719608002251	journal	October 1996
Production and use of nuclear tracks: imprinting structure on solids Fischer, Bernd Eberhard; Spohr, Reimar Reviews of Modern Physics, Vol. 55, Issue 4 https://doi.org/10.1103/RevModPhys.55.907	journal	October 1983
A Method for Reproducibly Preparing Synthetic Nanopores for Resistive-Pulse Biosensors Wharton, John E.; Jin, Pu; Sexton, Lindsay T. Small, Vol. 3, Issue 8 https://doi.org/10.1002/smll.200700106	journal	August 2007
Conical Nanopore Membranes. Preparation and Transport Properties Li, Naichao; Yu, Shufang; Harrell, C. Chad Analytical Chemistry, Vol. 76, Issue 7 https://doi.org/10.1021/ac035402e	journal	April 2004
Conical Nanopore Membranes: Controlling the Nanopore Shape Harrell, C. Chad; Siwy, Zuzanna S.; Martin, Charles R. Small, Vol. 2, Issue 2 https://doi.org/10.1002/smll.200500196	journal	February 2006
Electroosmotic Flow Rectification in Membranes with Asymmetrically Shaped Pores: Effects of Current and Pore Density Bishop, Gregory W.; Lopez, Marcos M.; Ramiah Rajasekaran, Pradeep The Journal of Physical Chemistry C, Vol. 119, Issue 29 https://doi.org/10.1021/acs.jpcc.5b03510	journal	July 2015
Electroosmotic Flow Rectification in Pyramidal-Pore Mica Membranes Jin, Pu; Mukaibo, Hitomi; Horne, Lloyd P. Journal of the American Chemical Society, Vol. 132, Issue 7 https://doi.org/10.1021/ja909335r	journal	February 2010
Nanofluidic Diode Vlassiouk, Ivan; Siwy, Zuzanna S. Nano Letters, Vol. 7, Issue 3 https://doi.org/10.1021/nl062924b	journal	March 2007
Ion Current Rectification at Nanopores in Glass Membranes White, Henry S.; Bund, Andreas Langmuir, Vol. 24, Issue 5 https://doi.org/10.1021/la702955k	journal	March 2008
Capillary zone electrophoresis Jorgenson, J.; Lukacs, K. Science, Vol. 222, Issue 4621 https://doi.org/10.1126/science.6623076	journal	October 1983
Electrokinetic Flow in a Narrow Cylindrical Capillary Rice, C. L.; Whitehead, R. The Journal of Physical Chemistry, Vol. 69, Issue 11 https://doi.org/10.1021/j100895a062	journal	November 1965
Controlling Electroosmotic Flow in Microchannels with pH-Responsive Polyelectrolyte Multilayers Sui, Zhijie; Schlenoff, Joseph B. Langmuir, Vol. 19, Issue 19 https://doi.org/10.1021/la034682q	journal	September 2003
Conical-Nanotube Ion-Current Rectifiers: The Role of Surface Charge Siwy, Zuzanna; Heins, Elizabeth; Harrell, C. Chad Journal of the American Chemical Society, Vol. 126, Issue 35 https://doi.org/10.1021/ja047675c	journal	September 2004
Electroosmotic Flow in Template-Prepared Carbon Nanotube Membranes Miller, Scott A.; Young, Vaneica Y.; Martin, Charles R. Journal of the American Chemical Society, Vol. 123, Issue 49, p. 12335-12342 https://doi.org/10.1021/ja011926p	journal	December 2001
Nanofluidic diodes Cheng, Li-Jing; Guo, L. Jay Chem. Soc. Rev., Vol. 39, Issue 3 https://doi.org/10.1039/B822554K	journal	January 2010
A nanodevice for rectification and pumping ions Siwy, Zuzanna; Fuliński, Andrzej American Journal of Physics, Vol. 72, Issue 5 https://doi.org/10.1119/1.1648328	journal	May 2004
Electroosmotic flow rectification in conical nanopores Laohakunakorn, Nadanai; Keyser, Ulrich F. Nanotechnology, Vol. 26, Issue 27 https://doi.org/10.1088/0957-4484/26/27/275202	journal	June 2015
Negative Incremental Resistance Induced by Calcium in Asymmetric Nanopores Siwy, Zuzanna S.; Powell, Matthew R.; Kalman, Eric Nano Letters, Vol. 6, Issue 3 https://doi.org/10.1021/nl0524290	journal	March 2006
Calorimetric titration study of the interaction of several uni- and bivalent cations with 15-crown-5, 18-crown-6, and two isomers of dicyclohexo-18-crown-6 in aqueous solution at 25.degree.C and .mu. = 0.1 Izatt, R. M.; Terry, R. E.; Haymore, B. L. Journal of the American Chemical Society, Vol. 98, Issue 24 https://doi.org/10.1021/ja00440a028	journal	November 1976
Voltage Charging Enhances Ionic Conductivity in Gold Nanotube Membranes Gao, Peng; Martin, Charles R. ACS Nano, Vol. 8, Issue 8 https://doi.org/10.1021/nn502642m	journal	July 2014
Effect of Crown Ether on Ion Currents through Synthetic Membranes Containing a Single Conically Shaped Nanopore Heins, Elizabeth A.; Baker, Lane A.; Siwy, Zuzanna S. The Journal of Physical Chemistry B, Vol. 109, Issue 39 https://doi.org/10.1021/jp052341a	journal	October 2005
Electric-field-induced wetting and dewetting in single hydrophobic nanopores Powell, Matthew R.; Cleary, Leah; Davenport, Matthew Nature Nanotechnology, Vol. 6, Issue 12 https://doi.org/10.1038/nnano.2011.189	journal	October 2011

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