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Title: Systems, devices, and methods for agglutination assays using sedimentation

Patent ·
OSTI ID:1465194

Embodiments of the present invention include methods for conducting agglutination assays using sedimentation. Aggregates may be exposed to sedimentation forces and travel through a density medium to a detection area. Microfluidic devices, such as microfluidic disks, are described for conducting the agglutination assays, as are systems for conducting the assays.

Research Organization:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC04-94AL85000
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
Patent Number(s):
10,024,849
Application Number:
14/853,660
OSTI ID:
1465194
Resource Relation:
Patent File Date: 2015 Sep 14
Country of Publication:
United States
Language:
English

References (18)

Fully Integrated Lab-on-a-Disc for Nucleic Acid Analysis of Food-Borne Pathogens journal March 2014
Apparatus and method for carrying out analysis of samples patent April 1999
Diagnostic Analyzers With Pretreatment Carousels and Related Methods patent-application September 2014
Microfluidics devices and methods for performing cell based assays patent-application August 2002
Capillary columns with in situ formed porous monolithic packing for micro high-performance liquid chromatography and capillary electrochromatography journal September 1999
Detection of Listeria monocytogenes and the toxin listeriolysin O in food journal February 2006
Design Strategies and Performance of Custom DNA Sequencing Primers journal September 1999
Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay patent June 1997
Protecting agent patent-application August 2005
Microfluidic particle-analysis systems patent-application April 2004
Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays journal January 2007
Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system patent November 2001
Systems and Methods for Handling Microfluidic Droplets patent-application October 2013
Multi-parameter assays including analysis discs and methods relating thereto patent-application October 2002
Centrifugal Microfluidic Platform for Ultrasensitive Detection of Botulinum Toxin journal December 2014
Centrifugation Apparatus For Containers Of Biological Material patent-application February 2011
Loading Disk for Photometric Analyzer of Rotary Cuvette Type patent July 1973
Centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids patent February 2008