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Title: DNA/RNA sequencing using a semiconducting nanopore

Patent ·
OSTI ID:1456913

The present disclosure provides novel apparatus including, though not necessarily limited to, biosensors utilizing semiconductor materials in electrolyte solutions and methods for using the same. The biosensors rely on a unique property wherein a charged body in the electrolyte solution produces a detectable change in the local conductivity of the semiconductor as the body approaches or travels near the semiconductor.

Research Organization:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
DE-AC04-94AL85000
Assignee:
Fleharty; Petsev; Dimiter N. ; Van Swol; Frank B.
Patent Number(s):
9,988,677
Application Number:
14/735,898
OSTI ID:
1456913
Resource Relation:
Patent File Date: 2015 Jun 10
Country of Publication:
United States
Language:
English

References (6)

Nanopore sequencing using ratiometric impedance patent April 2015
Accurate integrated low-cost electrode chips for point-of-need analysis and a method of utilization in hot electron-induced electrochemiluminescent systems patent June 2016
Methods of detecting target nucleic acids patent June 2017
Fabrication of molecular scale devices using fluidic assembly patent-application February 2003
Methods and device for analyte characterization patent-application December 2005
Methods of Detecting Target Nucleic Acids patent-application November 2010