Bis-polymer lipid-peptide conjugates and nanoparticles thereof
Patent
·
OSTI ID:1436688
The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can self-assemble to form helix bundle subunits, which in turn assemble to provide micellar nanocarriers for drug cargos and other agents. Particles containing the conjugates and methods for forming the particles are also disclosed.
- Research Organization:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC02-05CH11231
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Number(s):
- 9,949,927
- Application Number:
- 14/490,336
- OSTI ID:
- 1436688
- Resource Relation:
- Patent File Date: 2014 Sep 18
- Country of Publication:
- United States
- Language:
- English
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