Optoelectronic system and apparatus for connection to biological systems

Okandan, Murat; Nielson, Gregory N.

Title: Optoelectronic system and apparatus for connection to biological systems

Patent · Tue Mar 06 00:00:00 EST 2018

OSTI ID:1425935

Okandan, Murat; Nielson, Gregory N.

The present invention relates to a biological probe structure, as well as apparatuses, systems, and methods employing this structure. In particular embodiments, the structure includes a hermetically sealed unit configured to receive and transmit one or more optical signals. Furthermore, the structure can be implanted subcutaneously and interrogated externally. In this manner, a minimally invasive method can be employed to detect, treat, and/or assess the biological target. Additional methods and systems are also provided.

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Research Organization:: Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)

Patent Number(s):: 9,907,496

Application Number:: 14/314,176

OSTI ID:: 1425935

Resource Relation:: Patent File Date: 2014 Jun 25

Country of Publication:: United States

Language:: English

References (150)

Photovoltaic solar cell Nielson, Gregory N.; Cruz-Campa, Jose Luis; Okandan, Murat https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8728857 US Patent Document 8,728,857	patent	May 2014
Double nerve intraneural interface implant on a human amputee for robotic hand control Rossini, Paolo M.; Micera, Silvestro; Benvenuto, Antonella Clinical Neurophysiology, Vol. 121, Issue 5, p. 777-783 https://doi.org/10.1016/j.clinph.2010.01.001	journal	May 2010
Methods for improved preconcentrators Manginell, Ronald P.; Lewis, Patrick R.; Okandan, Murat https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7727314 US Patent Document 7,727,314	patent	June 2010
3D microstructures integrated with optical waveguides and photodiodes on silicon Muller, R.; Pavelescu, I.; Manea, E. MELECON '98. 9th Mediterranean Electrotechnical Conference https://doi.org/10.1109/MELCON.1998.692441	conference	January 1998
Integrated optics on silicon for sensor applications Cristea, D.; Caldararu, M.; Paraschiv, A. MELECON '98. 9th Mediterranean Electrotechnical Conference https://doi.org/10.1109/MELCON.1998.699477	conference	January 1998
Method and apparatus for measuring gate leakage current in an integrated circuit Okandan, Murat; Campbell, Jr., Jules D. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6348806 US Patent Document 6,348,806	patent	February 2002
Systems, methods and compositions for optical stimulation of target cells Deisseroth, Karl; Zhang, Feng; Gradinaru, Viviana https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8603790 US Patent Document 8,603,790	patent	December 2013
In vivo delivery of neurotransmitters by implanted, encapsulated cells Aebischer, Patrick; Winn, Shelley R.; Galletti, Pierre M. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4892538 US Patent Document 4,892,538	patent	January 1990
Optical microcavities Vahala, Kerry J. Nature, Vol. 424, Issue 6950, p. 839-846 https://doi.org/10.1038/nature01939	journal	August 2003
Ultrathin and micro-sized solar cell performance optimization via simulations: Ultrathin, micro-sized solar cell performance optimization Cruz-Campa, Jose L.; Nielson, Gregory N.; Resnick, Paul J. Progress in Photovoltaics: Research and Applications, Vol. 21, Issue 5 https://doi.org/10.1002/pip.2214	journal	June 2012
Structured wafer for device processing Okandan, Murat; Nielson, Gregory N. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8729673 US Patent Document 8,729,673	patent	May 2014
Micromachined spinneret Okandan, Murat; Galambos, Paul C. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7291003 US Patent Document 7,291,003	patent	November 2007
Photo-Voltaic System Using Micro-Optics Sweatt, William C.; Jared, Bradley H.; Anderson, Benjamin J. Optics for Solar Energy 2012 https://doi.org/10.1364/OSE.2012.SM2A.1	conference	January 2012
Microelectromechanical inertial sensor Okandan, Murat; Nielson, Gregory N. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8205497 US Patent Document 8,205,497	patent	June 2012
Thermal analysis of injectable, cellular-scale optoelectronics with pulsed power Li, Y.; Shi, X.; Song, J. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 469, Issue 2156, Article No. 20130142 https://doi.org/10.1098/rspa.2013.0142	journal	May 2013
Micro-machined resonator oscillator Koehler, Dale R.; Sniegowski, Jeffry J.; Bivens, Hugh M. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5339051 US Patent Document 5,339,051	patent	August 1994
Brain-Machine Interface Based on Photonic Neural Probe Arrays Roukes, Michael L. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130085398 US Patent Application 13/627755; 20130085398	patent-application	April 2013
Device With Integrated Multi-Fiber Optical Probe and Methods of Use Bigio, Irving; Singh, Satish https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20090326384 US Patent Application 12/374175; 20090326384	patent-application	December 2009
Solar cell with back side contacts Nielson, Gregory N.; Okandan, Murat; Cruz-Campa, Jose Luis https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8614395 US Patent Document 8,614,395	patent	December 2013
Engineering Approaches to Illuminating Brain Structure and Dynamics Deisseroth, Karl; Schnitzer, Mark J. Neuron, Vol. 80, Issue 3, p. 568-577 https://doi.org/10.1016/j.neuron.2013.10.032	journal	October 2013
Radiation Response of a Gate-All-Around Silicon Nano-Wire Transistor Draper, Bruce; Okandan, Murat; Shaneyfelt, Marty IEEE Transactions on Nuclear Science, Vol. 56, Issue 6, p. 3274-3279 https://doi.org/10.1109/TNS.2009.2033917	journal	December 2009
Fiber optic needle probes for optical coherence tomography imaging Pitris, Constantinos; Boppart, Stephen A.; Li, Xingde https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6564087 US Patent Document 6,564,087	patent	May 2003
Surface-micromachined microfluidic devices Galambos, Paul C.; Okandan, Murat; Montague, Stephen https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6797187 US Patent Document 6,797,187	patent	September 2004
Interface for a-Si waveguides and III/V waveguides Kwakernaak, Martin; Chan, Winston Kong; Capewell, David https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7773840 US Patent Document 7,773,840	patent	August 2010
Broadband optical fiber tap based on cladding-mode coupling Zhang, Chunshu; Chiang, Kin-Seng Optical Engineering, Vol. 51, Issue 7, Article No. 075001 https://doi.org/10.1117/1.OE.51.7.075001	journal	July 2012
Micro-fluidic interconnect Okandan, Murat; Galambos, Paul C.; Benavides, Gilbert L. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7004198 US Patent Document 7,004,198	patent	February 2006
Micromachined electrode array Okandan, Murat; Wessendorf, Kurt O. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7308317 US Patent Document 7,308,317	patent	December 2007
Photo-responsive systems and biomaterials: photochromic polymers, light-triggered self-assembly, surface modification, fluorescence modulation and beyond Ercole, Francesca; Davis, Thomas P.; Evans, Richard A. Polymer Chemistry, Vol. 1, Issue 1, p. 37-54 https://doi.org/10.1039/B9PY00300B	journal	January 2010
Fabrication of lattice mismatched multijunction photovoltaic cells using 3D integration concepts Cruz-Campa, Jose L.; Nielson, Gregory N.; Lentine, Anthony L. 2012 38th IEEE Photovoltaic Specialists Conference https://doi.org/10.1109/PVSC.2012.6317755	conference	June 2012
Photovoltaic solar concentrator Nielson, Gregory N.; Okandan, Murat; Resnick, Paul J. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8329503 US Patent Document 8,329,503	patent	December 2012
Objectives, criteria and methods for the design of the SmartHand transradial prosthesis Cipriani, Christian; Controzzi, Marco; Carrozza, Maria Chiara Robotica, Vol. 28, Issue 06, p. 919-927 https://doi.org/10.1017/S0263574709990750	journal	December 2009
Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics Kim, T.-i.; McCall, J. G.; Jung, Y. H. Science, Vol. 340, Issue 6129, p. 211-216 https://doi.org/10.1126/science.1232437	journal	April 2013
Ultra-small optical probes, imaging optics, and methods for using same Swanson, Eric; Petersen, Christopher; McNamara, Edward https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6445939 US Patent Document 6,445,939	patent	September 2002
Optically transduced MEMS gyro device Nielson, Gregory N.; Bogart, Gregory R.; Langlois, Eric https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8726730 US Patent Document 8,726,730	patent	May 2014
Micromachined Neural Probes Masmanidis, Sotiris K.; Du, Jiangang; Rouke, Michael L, https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20090177144 US Patent Application 12/335847; 20090177144	patent-application	July 2009
Optically Interrogated Solid State Biosensors Incorporating Porous Materials - Devices and Methods of Fabrication Hajj-Hassan, Mohamad; Chodavarapu, Vamsy; Musallam, Sam https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20110024771 US Patent Application 12/827216; 20110024771	patent-application	February 2011
Long-term cortical recordings with microactuated microelectrodes Jackson, Nathan; Stice, Paula; Okandan, Murat 2007 3rd International IEEE/EMBS Conference on Neural Engineering https://doi.org/10.1109/CNE.2007.369632	conference	May 2007
Control of Hand Prostheses Using Peripheral Information Micera, Silvestro; Carpaneto, Jacopo; Raspopovic, Stanisa IEEE Reviews in Biomedical Engineering, Vol. 3, p. 48-68 https://doi.org/10.1109/RBME.2010.2085429	journal	January 2010
Optogenetic Probes for Measuring Membrane Potential Cohen, Adam E.; Kralj, Joel M.; Douglass, Adam D. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130224756 US Patent Application 13/818432; 20130224756	patent-application	August 2013
Electrochemical Detection of the Neurotransmitter Dopamine by Nanoimprinted Interdigitated Electrodes and a CMOS Circuit With Enhanced Collection Efficiency Huang, Chang-Wen; Lu, Michael S.-C. IEEE Sensors Journal, Vol. 11, Issue 9, p. 1826-1831 https://doi.org/10.1109/JSEN.2011.2105260	journal	September 2011
Micro-concentrators for a microsystems-enabled photovoltaic system Jared, Bradley H.; Saavedra, Michael P.; Anderson, Ben J. Optics Express, Vol. 22, Issue S2, p. A521-A527 https://doi.org/10.1364/OE.22.00A521	journal	January 2014
Electrostatic Microactuators for Precise Positioning of Neural Microelectrodes Muthuswamy, J.; Okandan, M.; Jain, T. IEEE Transactions on Biomedical Engineering, Vol. 52, Issue 10, p. 1748-1755 https://doi.org/10.1109/TBME.2005.855712	journal	October 2005
Lithographically defined microporous carbon structures Burckel, David Bruce; Washburn, Cody M.; Polsky, Ronen https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8349547 US Patent Document 8,349,547	patent	January 2013
Microscale PV Cells for Concentrated PV Applications Nielson, G. N.; Okandan, M.; Resnick, P. J. 24th European Photovoltaic Solar Energy Conference, p. 170-173 https://doi.org/10.4229/24thEUPVSEC2009-1BO.8.1	conference	September 2009
Optical-based sensing devices Colvin, Jr., Arthur E.; Dale, Gregory A.; Zerwekh, Paul Samuel https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6330464 US Patent Document 6,330,464	patent	December 2001
Surface and Bulk-Silicon-Micromachined Optical Displacement Sensor Fabricated With the SwIFT-Lite™ Process Hall, N. A.; Okandan, M.; Degertekin, F. L. Journal of Microelectromechanical Systems, Vol. 15, Issue 4, p. 770-776 https://doi.org/10.1109/JMEMS.2006.878884	journal	August 2006
Intracranial neural interface system Kipke, Daryl R.; Williams, Justin; Hetke, Jamille Farraye https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7979105 US Patent Document 7,979,105	patent	July 2011
Microactuated neural probes to compensate for brain micromotion Muthuswamy, J.; Gilletti, A.; Jain, T. Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society https://doi.org/10.1109/IEMBS.2003.1279819	conference	January 2003
Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins Mattis, Joanna; Tye, Kay M.; Ferenczi, Emily A. Nature Methods, Vol. 9, Issue 2, p. 159-172 https://doi.org/10.1038/nmeth.1808	journal	December 2011
Light Emitting Diode Growth on Curved Gallium Nitride Surfaces Rodak, L. E.; Lee, K.; Kumbham, V. MRS Proceedings, Vol. 1288 https://doi.org/10.1557/opl.2011.286	journal	January 2011
Method and apparatus testing IC chips for damage during fabrication Fonash, Stephen J.; Awadelkarim, Osama O.; Okandan, Murat https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5994911 US Patent Document 5,994,911	patent	November 1999
Electrothermal Microactuators With Peg Drive Improve Performance for Brain Implant Applications Anand, Sindhu; Sutanto, Jemmy; Baker, Michael S. Journal of Microelectromechanical Systems, Vol. 21, Issue 5, p. 1172-1186 https://doi.org/10.1109/JMEMS.2012.2203789	journal	October 2012
Microscale c-Si (c)PV cells for low-cost power Nielson, Gregory N.; Okandan, Murat; Resnick, Paul 2009 34th IEEE Photovoltaic Specialists Conference (PVSC) https://doi.org/10.1109/PVSC.2009.5411500	conference	June 2009
Hybrid integration of silicon nanophotonics with 40nm-CMOS VLSI drivers and receivers Thacker, Hiren D.; Shubin, Ivan; Luo, Ying 2011 IEEE 61st Electronic Components and Technology Conference (ECTC) https://doi.org/10.1109/ECTC.2011.5898607	conference	May 2011
Surface micro-machined polysilicon probes for neurophysiology Muthuswamy, J.; Okandan, M.; McBrayer, J. Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society https://doi.org/10.1109/IEMBS.2000.900722	conference	January 2000
Optically transduced MEMS magnetometer Nielson, Gregory N.; Langlois, Eric https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8674689 US Patent Document 8,674,689	patent	March 2014
Recent developments in optical fiber sensing using fiber Bragg gratings Brady, G. P.; Kalli, Kyriacos; Webb, David J. SPIE's 1996 International Symposium on Optical Science, Engineering, and Instrumentation, SPIE Proceedings https://doi.org/10.1117/12.255350	conference	October 1996
A glass-coated tungsten microelectrode enclosing optical fibers for optogenetic exploration in primate deep brain structures Tamura, Keita; Ohashi, Yohei; Tsubota, Tadashi Journal of Neuroscience Methods, Vol. 211, Issue 1, p. 49-57 https://doi.org/10.1016/j.jneumeth.2012.08.004	journal	October 2012
Optical probing of neuronal connections with fluorescent indicators Yuste, Rafael; Peterlin, Zita https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6662039 US Patent Document 6,662,039	patent	December 2003
System and Method for Optical Stimulation of Neural Tissues Mahadevan-Jansen, Anita; Wells, Johnson D.; Jansen, E. Duco https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140024902 US Patent Application 13/117850; 20140024902	patent-application	January 2014
216 cell microconcentrator module with moderate concentration, ±4° acceptance angle, and 13.3 mm focal length Nielson, Gregory N.; Okandan, Murat; Cruz-Campa, Jose L. 2013 IEEE 39th Photovoltaic Specialists Conference (PVSC) https://doi.org/10.1109/PVSC.2013.6744191	conference	June 2013
Implantable Wireless Neural Device Nurmikko, Arto V.; Yin, Ming; Patterson, William R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140094674 US Patent Application 14/028178; 20140094674	patent-application	April 2014
Light scattering study of tissues Tuchin, Valerii V. Physics-Uspekhi, Vol. 40, Issue 5, p. 495-515 https://doi.org/10.1070/PU1997v040n05ABEH000236	journal	May 1997
Electrode array for neural stimulation Wessendorf, Kurt O.; Okandan, Murat; Stein, David J. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8000804 US Patent Document 8,000,804	patent	August 2011
Optical Fibers Functionalized with Photonic Crystal Resonant Optical Structures Shambat, Gary; Vuckovic, Jelena https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130039616 US Patent Application 13/569567; 20130039616	patent-application	February 2013
MEMS fluidic actuator Kholwadwala, Deepesh K.; Johnston, Gabriel; Rohrer, Brandon R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7246524 US Patent Document 7,246,524	patent	July 2007
InGaAs PIN photodetectors integrated on silicon-on-insulator waveguides Sheng, Zhen; Liu, Liu; Brouckaert, Joost Optics Express, Vol. 18, Issue 2, p. 1756-1761 https://doi.org/10.1364/OE.18.001756	journal	January 2010
Photovoltaic Power Generation System Free of Bypass Diodes Lentine, Anthony L.; Okandan, Murat; Nielsen, Gregory N. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130269747 US Patent Application 13/543297; 20130269747	patent-application	October 2013
Ultra-thin single crystal silicon modules capable of 450 W/kg and bending radii <1mm: Fabrication and characterization Cruz-Campa, Jose L.; Nielson, Gregory N.; Okandan, Murat 2013 IEEE 39th Photovoltaic Specialists Conference (PVSC) https://doi.org/10.1109/PVSC.2013.6744359	conference	June 2013
Microfabrication of microsystem-enabled photovoltaic (MEPV) cells Nielson, Gregory N.; Okandan, Murat; Cruz-Campa, Jose L. SPIE MOEMS-MEMS https://doi.org/10.1117/12.876422	conference	February 2011
Photovoltaic system Nielson, Gregory N.; Okandan, Murat; Lentine, Anthony L. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8736108 US Patent Document 8,736,108	patent	May 2014
Failure Analysis Techniques for Microsystems-Enabled Photovoltaics Yang, Benjamin B.; Cruz-Campa, Jose L.; Haase, Gaddi S. IEEE Journal of Photovoltaics, Vol. 4, Issue 1, p. 470-476 https://doi.org/10.1109/JPHOTOV.2013.2284864	journal	January 2014
Surface-micromachined microfluidic devices Galambos, Paul C.; Okandan, Murat; Montague, Stephen https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6537437 US Patent Document 6,537,437	patent	March 2003
Silicon opto-FET coupled to waveguides for integrated optical microsystems Cristea, Dana; Craciunoiu, Florea Photonics China '98 https://doi.org/10.1117/12.317991	conference	August 1998
Wafer-scale integration of group III–V lasers on silicon using transfer printing of epitaxial layers Justice, John; Bower, Chris; Meitl, Matthew Nature Photonics, Vol. 6, Issue 9, p. 610-614 https://doi.org/10.1038/nphoton.2012.204	journal	August 2012
Optical fiber tap with integral reflecting surface and method of making same Poole, Craig D. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6535671 US Patent Document 6,535,671	patent	March 2003
Nanoelectrodes, nanoelectrode arrays and their applications Arrigan, Damien W. M. The Analyst, Vol. 129, Issue 12, p. 1157-1165 https://doi.org/10.1039/b415395m	journal	January 2004
Optical Platform for Simultaneously Stimulating, Manipulating, and Probing Multiple Living Cells in Complex Biological Systems Wang, Sheng; Sun, Cheng; Zhang, Xiang https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20100292931 US Patent Application 12/774856; 20100292931	patent-application	November 2010
The Optics of Human Skin Anderson, R. Rox; Parrish, John A. Journal of Investigative Dermatology, Vol. 77, Issue 1, p. 13-19 https://doi.org/10.1111/1523-1747.ep12479191	journal	July 1981
Neural stimulation and optical monitoring systems and methods Sloan, Leif R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7729773 US Patent Document 7,729,773	patent	June 2010
Polymers for neural implants Hassler, Christina; Boretius, Tim; Stieglitz, Thomas Journal of Polymer Science Part B: Polymer Physics, Vol. 49, Issue 1, p. 18-33 https://doi.org/10.1002/polb.22169	journal	November 2010
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches Szymański, Wiktor; Beierle, John M.; Kistemaker, Hans A. V. Chemical Reviews, Vol. 113, Issue 8, p. 6114-6178 https://doi.org/10.1021/cr300179f	journal	April 2013
Monolithic Bi-directional Linear Microactuator for Light Beam Manipulation Cheng, Hao-Der; Hsiao, Sheng-Yi; Wu, Mingching IEEE/LEOS International Conference on Optical MEMS and Their Applications Conference https://doi.org/10.1109/OMEMS.2006.1708295	conference	January 2006
Back-contacted and small form factor GaAs solar cell Cruz-Campa, J. L.; Nielson, G. N.; Okandan, M. 2010 35th IEEE Photovoltaic Specialists Conference https://doi.org/10.1109/PVSC.2010.5614184	conference	June 2010
Growth and optical properties of axial hybrid III–V/silicon nanowires Hocevar, Moïra; Immink, George; Verheijen, Marcel Nature Communications, Vol. 3, Article No. 1266 https://doi.org/10.1038/ncomms2277	journal	January 2012
Hybrid Clustered Neural Interface System Anderson, David; Kipke, Daryl R.; Hetke, Jamille https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20120323288 US Patent Application 13/524989; 20120323288	patent-application	December 2012
An implantable neural interface with electromagnetic stimulation capabilities Accoto, D.; Francomano, M. T.; Rainer, A. Medical Hypotheses, Vol. 81, Issue 2, p. 322-327 https://doi.org/10.1016/j.mehy.2013.04.008	journal	August 2013
The SmartHand transradial prosthesis Cipriani, Christian; Controzzi, Marco; Carrozza, Maria Chiara Journal of NeuroEngineering and Rehabilitation, Vol. 8, Issue 1, Article No. 29 https://doi.org/10.1186/1743-0003-8-29	journal	January 2011
Ultrathin Flexible Crystalline Silicon: Microsystems-Enabled Photovoltaics Cruz-Campa, Jose L.; Nielson, Gregory N.; Resnick, Paul J. IEEE Journal of Photovoltaics, Vol. 1, Issue 1, p. 3-8 https://doi.org/10.1109/JPHOTOV.2011.2162973	journal	July 2011
System for optical stimulation of target cells Deisseroth, Karl; Zhang, Feng; Boyden, Edward S. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8398692 US Patent Document 8,398,692	patent	March 2013
Photovoltaic solar cell Nielson, Gregory N.; Okandan, Murat; Cruz-Campa, Jose Luis https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8592249 US Patent Document 8,592,249	patent	November 2013
Hybrid optical-electrical probes for stimulation of nerve or other animal tissue Bendett, Mark P.; Webb, James S. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8357187 US Patent Document 8,357,187	patent	January 2013
Integrated Optical Neural Probe Jamieson, Brian; Mateo, Jennette https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130030274 US Patent Application 13/190441; 20130030274	patent-application	January 2013
Apparatus and method for transforming living cells Okandan, Murat; Galambos, Paul C. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6645757 US Patent Document 6,645,757	patent	November 2003
CLARITY for mapping the nervous system Chung, Kwanghun; Deisseroth, Karl Nature Methods, Vol. 10, Issue 6, p. 508-513 https://doi.org/10.1038/nmeth.2481	journal	June 2013
Flexible retinal electrode array Okandan, Murat; Wessendorf, Kurt O.; Christenson, Todd R. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7127301 US Patent Document 7,127,301	patent	October 2006
Nonhermetic Encapsulation Materials for MEMS-Based Movable Microelectrodes for Long-Term Implantation in the Brain Jackson, N.; Anand, S.; Okandan, M. Journal of Microelectromechanical Systems, Vol. 18, Issue 6, p. 1234-1245 https://doi.org/10.1109/JMEMS.2009.2030075	journal	December 2009
Nanolasers grown on silicon Chen, Roger; Tran, Thai-Truong D.; Ng, Kar Wei Nature Photonics, Vol. 5, Issue 3, p. 170-175 https://doi.org/10.1038/nphoton.2010.315	journal	February 2011
Wavelength Interrogator for Optical Sensors Based on a Novel Thermo-Optic Tunable Filter in SOI Passaro, Vittorio M. N.; Tsarev, Andrei V.; De Leonardis, Francesco Journal of Lightwave Technology, Vol. 30, Issue 13, p. 2143-2150 https://doi.org/10.1109/JLT.2012.2192907	journal	July 2012
Micro-unmanned aerodynamic vehicle Reuel, Nigel; Lionberger, Troy A.; Galambos, Paul C. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7341222 US Patent Document 7,341,222	patent	March 2008
Cost analysis for flat-plate concentrators employing microscale photovoltaic cells Paap, Scott; Gupta, Vipin; Cruz-Campa, Jose Luis 2013 IEEE 39th Photovoltaic Specialists Conference (PVSC) https://doi.org/10.1109/PVSC.2013.6745185	conference	June 2013
Prosthetic system for therapeutic optical activation and silencing of genetically-targeted neurons Boyden, Edward S.; Bernstein, Jacob G.; Henninger, Michael https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20090210039 US Patent Application 12/355745; 20090210039	patent-application	August 2009
Fiber-Coupled Light-Emitting Diode With a Capillary-Bonded Hemispherical Lens Zhu, L.; Huang, S. Y.; Lai, P. T. IEEE Photonics Technology Letters, Vol. 23, Issue 24, p. 1857-1859 https://doi.org/10.1109/LPT.2011.2170407	journal	December 2011
Resistance considerations for stacked small multi-junction photovoltaic cells Tauke-Pedretti, Anna; Cederberg, Jeffrey; Nielson, Gregory 2013 IEEE 39th Photovoltaic Specialists Conference (PVSC) https://doi.org/10.1109/PVSC.2013.6744895	conference	June 2013
Organic bioelectronics for electronic-to-chemical translation in modulation of neuronal signaling and machine-to-brain interfacing Larsson, Karin C.; Kjäll, Peter; Richter-Dahlfors, Agneta Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1830, Issue 9, p. 4334-4344 https://doi.org/10.1016/j.bbagen.2012.11.024	journal	September 2013
Fabrication and application of flexible, multimodal light-emitting devices for wireless optogenetics McCall, Jordan G.; Kim, Tae-il; Shin, Gunchul Nature Protocols, Vol. 8, Issue 12, p. 2413-2428 https://doi.org/10.1038/nprot.2013.158	journal	November 2013
On-chip optical interconnection by using integrated III-V laser diode and photodetector with silicon waveguide Ohira, Kazuya; Kobayashi, Kentaro; Iizuka, Norio Optics Express, Vol. 18, Issue 15, p. 15440-15447 https://doi.org/10.1364/OE.18.015440	journal	January 2010
III-V Semiconductor based MOEMS devices for optical telecommunications Garrigues, M.; Leclercq, J. L.; Viktorovitch, P. Microelectronic Engineering, Vol. 61-62, p. 933-945 https://doi.org/10.1016/S0167-9317(02)00545-2	journal	July 2002
Long-term neural recordings using MEMS based movable microelectrodes in the brain Jackson, Nathan; Sridharan, Arati; Anand, Sindhu Frontiers in Neuroengineering, Vol. 3, Article No. 10 https://doi.org/10.3389/fneng.2010.00010	journal	January 2010
Implantable Optical Stimulators Deisseroth, Karl; Schneider, M. Bret https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20090118800 US Patent Application 12/263044; 20090118800	patent-application	May 2009
Probe for Neural Recording and Optical Spectroscopic Interrogation McLaughlin, Bryan; LeBlanc, John https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20120287420 US Patent Application 13/434313; 20120287420	patent-application	November 2012
Miniaturized neural interfaces and implants Stieglitz, Thomas; Boretius, Tim; Ordonez, Juan SPIE MOEMS-MEMS https://doi.org/10.1117/12.912526	conference	June 2012
Optogenetic magnetic resonance imaging Deisseroth, Karl; Lee, Jin Hyung https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8696722 US Patent Document 8,696,722	patent	April 2014
Surface Micromachined Dielectrophoretic Gates for the Front-End Device of a Biodetection System James, Conrad D.; Okandan, Murat; Galambos, Paul Journal of Fluids Engineering, Vol. 128, Issue 1, p. 14-19 https://doi.org/10.1115/1.2136924	journal	January 2006
Concentrating Photovoltaic Systems Using Micro-Optics Sweatt, William; Nielson, Greg; Okandan, Marat Optics for Solar Energy 2011 https://doi.org/10.1364/OSE.2011.SRWC6	conference	January 2011
Neural Probe with Optical Stimulation Capability Yoon, Euisik; Cho, Il-Joo https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130079615 US Patent Application 13/510822; 20130079615	patent-application	March 2013
Single neuronal recordings using surface micromachined polysilicon microelectrodes Muthuswamy, Jit; Okandan, Murat; Jackson, Nathan Journal of Neuroscience Methods, Vol. 142, Issue 1, p. 45-54 https://doi.org/10.1016/j.jneumeth.2004.07.017	journal	March 2005
Micromachined patch-clamp apparatus Okandan, Murat https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8323955 US Patent Document 8,323,955	patent	December 2012
Micro-Optics for High-Efficiency Optical Performance and Simplified Tracking for Concentrated Photovoltaics (CPV) Sweatt, William; Jared, Bradley H.; Nielson, Greg N. International Optical Design Conference and Optical Fabrication and Testing https://doi.org/10.1364/IODC.2010.ITuC4	conference	January 2010
A chronic micropositioning system for neurophysiology Muthuswamy, J.; Salas, D.; Okandan, M. Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society https://doi.org/10.1109/IEMBS.2002.1053195	conference	January 2002
Nanophotonic Devices for Optical Interconnect Van Thourhout, Dries; Spuesens, Thijs; Selvaraja, Shankar Kumar IEEE Journal of Selected Topics in Quantum Electronics, Vol. 16, Issue 5, p. 1363-1375 https://doi.org/10.1109/JSTQE.2010.2040711	journal	September 2010
Demultiplexer circuit for neural stimulation Wessendorf, Kurt O.; Okandan, Murat; Pearson, Sean https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8285394 US Patent Document 8,285,394	patent	October 2012
Leveraging scale effects to create next-generation photovoltaic systems through micro- and nanotechnologies Nielson, Gregory N.; Okandan, Murat; Cruz-Campa, Jose Luis Proceedings Volume 8373, Micro- and Nanotechnology Sensors, Systems, and Applications IV, Vol. 8373, Article No: 837317 https://doi.org/10.1117/12.919464	conference	May 2012
Microlens rapid prototyping technique with capability for wide variation in lens diameter and focal length Cruz-Campa, J. L.; Okandan, M.; Busse, M. L. Microelectronic Engineering, Vol. 87, Issue 11, p. 2376-2381 https://doi.org/10.1016/j.mee.2010.04.012	journal	November 2010
Evaluating biocompatibility of semiconductive gallium nitride, flat and nano-structured silicon chips by cell viability, adhesion and growth Kang, Yu-Ting; Yen, Ta-Jen 2010 3rd International Nanoelectronics Conference (INEC) https://doi.org/10.1109/INEC.2010.5425190	conference	January 2010
Highly Multiplexed Optogenetic Neural Stimulation Using Integrated Optical Technologies Roukes, Michael L.; Fowler, Trevor; Arlett, Jessica L. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140142664 US Patent Application 14/086790; 20140142664	patent-application	May 2014
Optimal cell connections for improved shading, reliability, and spectral performance of microsystem enabled photovoltaic (MEPV) modules Lentine, Anthony L.; Nielson, Gregory N.; Okandan, Murat 2010 35th IEEE Photovoltaic Specialists Conference, p. 003048-003054 https://doi.org/10.1109/PVSC.2010.5614290	conference	November 2010
Implantable microtechnologies for the brain: Challenges and strategies for reliable operation Muthuswamy, Jit; Anand, Sindhu; Sutanto, Jemmy 2011 International Reliability Physics Symposium https://doi.org/10.1109/IRPS.2011.5784480	conference	April 2011
Silicon photonic Bragg-grating couplers for optical communications Shi, Wei; Veerasubramanian, Venkat; Plant, David V. SPIE OPTO https://doi.org/10.1117/12.2044096	conference	February 2014
Superconducting nanowire single-photon detectors: physics and applications Natarajan, Chandra M.; Tanner, Michael G.; Hadfield, Robert H. Superconductor Science and Technology, Vol. 25, Issue 6, Article No. 063001 https://doi.org/10.1088/0953-2048/25/6/063001	journal	April 2012
Structural and molecular interrogation of intact biological systems Chung, Kwanghun; Wallace, Jenelle; Kim, Sung-Yon Nature, Vol. 497, Issue 7449, p. 332-337 https://doi.org/10.1038/nature12107	journal	April 2013
Dynamically Reconfigurable Photovoltaic System Okandan, Murat; Nielson, Gregory N. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140060616 US Patent Application 14/014266; 20140060616	patent-application	March 2014
High Speed (GHz), Ultra-High Pressure (GPA) Sensor Array Fabricated in Integrated CMOS+MEMS Process Okandan, Murat; Olsson, Roy; Baker, Michael 2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems https://doi.org/10.1109/MEMSYS.2009.4805515	conference	January 2009
Gate-all-arround single-crystalline silicon nanowire optical sensor Ziaei-Moayyed, M.; Draper, B.; Okandan, M. Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS) https://doi.org/10.1109/TRANSDUCERS.2011.5969830	conference	June 2011
Microelectromechanical flow control apparatus Okandan, Murat https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7540469 US Patent Document 7,540,469	patent	June 2009
Transparent Contacts for Stacked Compound Photovoltaic Cells Tauke-Pedretti, Anna; Cederberg, Jeffrey; Nielson, Gregory N. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140102520 US Patent Application 13/649238; 20140102520	patent-application	April 2014
Integrated FET-Polysilicon Micromachining Process for Optical MEMS Cowan, W. D.; Resnick, P. J.; Okandan, M. IEEE/LEOS International Conference on Optical MEMS and Their Applications Conference https://doi.org/10.1109/OMEMS.2006.1708266	conference	January 2006
Tuned optical cavity magnetometer Okandan, Murat; Schwindt, Peter https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7826065 US Patent Document 7,826,065	patent	November 2010
Microsystems enabled photovoltaics: 14.9% efficient 14 μm thick crystalline silicon solar cell Cruz-Campa, Jose L.; Okandan, Murat; Resnick, Paul J. Solar Energy Materials and Solar Cells, Vol. 95, Issue 2, p. 551-558 https://doi.org/10.1016/j.solmat.2010.09.015	journal	February 2011
Microscale autonomous sensor and communications module Okandan, Murat; Nielson, Gregory N. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8680810 US Patent Document 8,680,810	patent	March 2014
MEMS-based miniature optical pickup Chiu, Yi; Chen, Cheng-Huan; Chiou, Jin-Chern IEEE Transactions on Magnetics, Vol. 41, Issue 2, p. 967-970 https://doi.org/10.1109/TMAG.2004.842077	journal	February 2005
Next Generation Photovoltaic Cells and System through MEMS Technology Nielson, Gregory N.; Okandan, Murat; Cruz-Campa, Jose L. ECS Transactions, Vol. 44, Issue 1, p. 1347-1352 https://doi.org/10.1149/1.3694470	journal	January 2012
Templated Chemically Deposited Semiconductor Optical Fiber Materials Sparks, Justin R.; Sazio, Pier J. A.; Gopalan, Venkatraman Annual Review of Materials Research, Vol. 43, Issue 1, p. 527-557 https://doi.org/10.1146/annurev-matsci-073012-125958	journal	July 2013
Processes for Multi-Layer Devices Utilizing Layer Transfer Nielson, Gregory N.; Sanchez, Carlos Anthony; Tauke-Pedretti, Anna https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140084450 US Patent Application 13/627425; 20140084450	patent-application	March 2014
Characterization of a 3D optrode array for infrared neural stimulation Abaya, T. V. F.; Diwekar, M.; Blair, S. Biomedical Optics Express, Vol. 3, Issue 9, p. 2200-2219 https://doi.org/10.1364/BOE.3.002200	journal	January 2012
Micromachining for optical and optoelectronic systems Wu, M. C. Proceedings of the IEEE, Vol. 85, Issue 11, p. 1833-1856 https://doi.org/10.1109/5.649660	journal	January 1997
Apparatus and Method for Optical Stimulation of Neural Tissues Mahdevan-Jansen, Anita; Wells, Jonathan D.; Jansen, E. Duce https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130245725 US Patent Application 13/893797; 20130245725	patent-application	September 2013
Implanting devices for the focal release of neuroinhibitory compounds Aebischer, Patrick; Tresco, Patrick A. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5474547 US Patent Document 5,474,547	patent	December 1995
Movable microprobes for the brain Muthuswamy, J.; Okandan, M.; Gilletti, A. 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology https://doi.org/10.1109/MMB.2005.1548390	conference	January 2005
Tools, methods, and applications for optophysiology in neuroscience Smedemark-Margulies, Niklas; Trapani, Josef G. Frontiers in Molecular Neuroscience, Vol. 6, Article No. 18 https://doi.org/10.3389/fnmol.2013.00018	journal	January 2013

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