Photoelectrochemical NADH Regeneration using Pt-Modified p -GaAs Semiconductor Electrodes

Stufano, Paolo; Paris, Aubrey R.; Bocarsly, Andrew

doi:10.1002/celc.201600488

Title: Photoelectrochemical NADH Regeneration using Pt-Modified p -GaAs Semiconductor Electrodes

Journal Article · Wed Feb 22 00:00:00 EST 2017 · ChemElectroChem

DOI:https://doi.org/10.1002/celc.201600488· OSTI ID:1418016

Stufano, Paolo ^[1]; Paris, Aubrey R. ^[1];

^[1]

Princeton Univ., NJ (United States). Frick Lab., Dept. of Chemistry

Abstract Cofactor regeneration in enzymatic reductions is crucial for the application of enzymes to both biological and energy‐related catalysis. Specifically, regenerating NADH from NAD ⁺ is of great interest, and using electrochemistry to achieve this end is considered a promising option. Here, we report the first example of photoelectrochemical NADH regeneration at the illuminated (λ>600 nm), metal‐modified, p ‐type semiconductor electrode Pt/ p ‐GaAs. Although bare p ‐GaAs electrodes produce only enzymatically inactive NAD ₂ , NADH was produced at the illuminated Pt‐modified p ‐GaAs surface. At low overpotential (−0.75 V vs. Ag/AgCl), Pt/ p ‐GaAs exhibited a seven‐fold greater faradaic efficiency for the formation of NADH than Pt alone, with reduced competition from the hydrogen evolution reaction. Improved faradaic efficiency and low overpotential suggest the possible utility of Pt/ p ‐GaAs in energy‐related NADH‐dependent enzymatic processes.

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Research Organization:: Princeton Univ., NJ (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES); National Science Foundation (NSF)

Grant/Contract Number:: SC0002133; DGE-1148900

OSTI ID:: 1418016

Alternate ID(s):: OSTI ID: 1401746

Journal Information:: ChemElectroChem, Vol. 4, Issue 5; ISSN 2196-0216

Publisher:: ChemPubSoc EuropeCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 16 works

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References (62)

New Photoproducts from Irradiation of NADH with Near-UV Light Vitinius, Ute; Schaffner, Kurt; Demuth, Martin Chemistry & Biodiversity, Vol. 1, Issue 10 https://doi.org/10.1002/cbdv.200490109	journal	October 2004
Plasmon-driven photoregeneration of cofactor molecules Sánchez-Iglesias, Ana; Chuvilin, Andrey; Grzelczak, Marek Chemical Communications, Vol. 51, Issue 25 https://doi.org/10.1039/C4CC07829B	journal	January 2015
Electrochemistry of Aqueous Pyridinium: Exploration of a Key Aspect of Electrocatalytic Reduction of CO ₂ to Methanol Yan, Yong; Zeitler, Elizabeth L.; Gu, Jing Journal of the American Chemical Society, Vol. 135, Issue 38 https://doi.org/10.1021/ja4064052	journal	September 2013
Catalytic effects for hydrogen photogeneration due to metallic deposition on P-GaAs Khader, M. International Journal of Hydrogen Energy, Vol. 21, Issue 7 https://doi.org/10.1016/0360-3199(95)00118-2	journal	July 1996
Biocatalytic Reductions and Chemical Versatility of the Old Yellow Enzyme Family of Flavoprotein Oxidoreductases Toogood, Helen S.; Gardiner, John M.; Scrutton, Nigel S. ChemCatChem, Vol. 2, Issue 8 https://doi.org/10.1002/cctc.201000094	journal	June 2010
Communication—Highly Efficient Electroenzymatic NADH Regeneration by an Electron-Relay Flavoenzyme Lee, Sumi; Choe, Hyunjun; Cho, Dae Haeng Journal of The Electrochemical Society, Vol. 163, Issue 5 https://doi.org/10.1149/2.0131606jes	journal	January 2016
Adsorption and electrochemical oxidation behaviour of NADH at a clean platinum electrode Jaegfeldt, Hans Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, Vol. 110, Issue 1-3 https://doi.org/10.1016/S0022-0728(80)80381-0	journal	July 1980
Direct electrochemical regeneration of the cofactor NADH on bare Ti, Ni, Co and Cd electrodes: The influence of electrode potential and electrode material Ali, Irshad; Khan, Tariq; Omanovic, Sasha Journal of Molecular Catalysis A: Chemical, Vol. 387 https://doi.org/10.1016/j.molcata.2014.02.029	journal	June 2014
Direct regeneration of NADH on a ruthenium modified glassy carbon electrode Azem, Amir; Man, Felise; Omanovic, Sasha Journal of Molecular Catalysis A: Chemical, Vol. 219, Issue 2 https://doi.org/10.1016/j.molcata.2004.04.041	journal	September 2004
Recent advances in the biocatalytic reduction of ketones and oxidation of sec -alcohols Kroutil, Wolfgang; Mang, Harald; Edegger, Klaus Current Opinion in Chemical Biology, Vol. 8, Issue 2 https://doi.org/10.1016/j.cbpa.2004.02.005	journal	April 2004
Electroenzymatic synthesis (regeneration of NADH coenzyme): Use of nafion ion exchange films for immobilization of enzyme and redox mediator Fry, Albert J.; Sobolov, Susan B.; Leonida, Mihaela D. Tetrahedron Letters, Vol. 35, Issue 31 https://doi.org/10.1016/S0040-4039(00)77258-3	journal	August 1994
Thermodynamics and kinetics of NAD+ adsorption on a glassy carbon electrode Ali, Irshad; Omanovic, Sasha Journal of Solid State Electrochemistry, Vol. 18, Issue 3 https://doi.org/10.1007/s10008-013-2331-9	journal	November 2013
Electrocatalytic reduction of NAD+ at glassy carbon electrode modified with single-walled carbon nanotubes and Ru(III) complexes Salimi, Abdollah; Izadi, Mohadeseh; Hallaj, Rahman Journal of Solid State Electrochemistry, Vol. 13, Issue 3 https://doi.org/10.1007/s10008-008-0583-6	journal	June 2008
Heterogeneous Catalysis Mediated Cofactor NADH Regeneration for Enzymatic Reduction Wang, Xiaodong; Yiu, Humphrey H. P. ACS Catalysis, Vol. 6, Issue 3 https://doi.org/10.1021/acscatal.5b02820	journal	February 2016
Evaluation of In Situ Electroenzymatic Regeneration of Coenzyme NADH in Packed Bed Membrane Reactors Chen, X.; Fenton, J. M.; Fisher, R. J. Journal of The Electrochemical Society, Vol. 151, Issue 2 https://doi.org/10.1149/1.1638386	journal	January 2004
Charge Transfer Process at Illuminated Semiconductor/Electrolyte Junctions Modified by Electrodeposition of Microscopic Metal Grain Allongue, P. Journal of The Electrochemical Society, Vol. 136, Issue 4 https://doi.org/10.1149/1.2096778	journal	January 1989
Cross-Linked LDH Crystals for Lactate Synthesis Coupled to Electroenzymatic Regeneration of NADH Sobolov, Susan B.; Leonida, Mihaela Draganoiu; Bartoszko-Malik, Anita The Journal of Organic Chemistry, Vol. 61, Issue 6 https://doi.org/10.1021/jo951408v	journal	January 1996
Optically transparent metallic catalysts on semiconductors Heller, Adam Pure and Applied Chemistry, Vol. 58, Issue 9 https://doi.org/10.1351/pac198658091189	journal	January 1986
Electrochemistry of synthetic analogues of NAD dimers Anne, A.; Hapiot, P.; Moiroux, J. Journal of Electroanalytical Chemistry, Vol. 331, Issue 1-2 https://doi.org/10.1016/0022-0728(92)85017-W	journal	January 1992
Cofactor regeneration for sustainable enzymatic biosynthesis Liu, Wenfang; Wang, Ping Biotechnology Advances, Vol. 25, Issue 4 https://doi.org/10.1016/j.biotechadv.2007.03.002	journal	July 2007
NAD/NADH as a model redox system: Mechanism, mediation, modification by the environment Elving, Philip J.; Bresnahan, William T.; Moiroux, Jacques Bioelectrochemistry and Bioenergetics, Vol. 9, Issue 3 https://doi.org/10.1016/0302-4598(82)80026-3	journal	July 1982
Enzymatic reductions for the chemist Hollmann, Frank; Arends, Isabel W. C. E.; Holtmann, Dirk Green Chemistry, Vol. 13, Issue 9 https://doi.org/10.1039/c1gc15424a	journal	January 2011
Nicotinamide adenine dinucleotide (NAD+) and related compounds. Electrochemical redox pattern and allied chemical behavior Schmakel, Conrad O.; Santhanam, K. S. V.; Elving, Philip J. Journal of the American Chemical Society, Vol. 97, Issue 18 https://doi.org/10.1021/ja00851a010	journal	September 1975
Recent progress in biocatalysis for asymmetric oxidation and reduction Matsuda, Tomoko; Yamanaka, Rio; Nakamura, Kaoru Tetrahedron: Asymmetry, Vol. 20, Issue 5 https://doi.org/10.1016/j.tetasy.2008.12.035	journal	March 2009
Hybrid Technologies for an Enhanced Carbon Recycling Based on the Enzymatic Reduction of CO2 to Methanol in Water: Chemical and Photochemical NADH Regeneration Dibenedetto, Angela; Stufano, Paolo; Macyk, Wojciech ChemSusChem, Vol. 5, Issue 2 https://doi.org/10.1002/cssc.201100484	journal	February 2012
Biocatalytic Oxidation of Primary and Secondary Alcohols Kroutil, Wolfgang; Mang, Harald; Edegger, Klaus Advanced Synthesis & Catalysis, Vol. 346, Issue 23 https://doi.org/10.1002/adsc.200303177	journal	February 2004
Practical chiral alcohol manufacture using ketoreductases Huisman, Gjalt W.; Liang, Jack; Krebber, Anke Current Opinion in Chemical Biology, Vol. 14, Issue 2 https://doi.org/10.1016/j.cbpa.2009.12.003	journal	April 2010
Direct electrochemical regeneration of the enzymatic cofactor 1,4-NADH employing nano-patterned glassy carbon/Pt and glassy carbon/Ni electrodes Ali, Irshad; Gill, Amardeep; Omanovic, Sasha Chemical Engineering Journal, Vol. 188 https://doi.org/10.1016/j.cej.2012.02.005	journal	April 2012
Semiconductor electrode modifications: influence on the state distribution at the interface Allongue, P.; Souteyrand, E. Electrochimica Acta, Vol. 34, Issue 12 https://doi.org/10.1016/0013-4686(89)85054-6	journal	December 1989
Photocatalytic Regeneration of Nicotinamide Cofactors by Quantum Dot–Enzyme Biohybrid Complexes Brown, Katherine A.; Wilker, Molly B.; Boehm, Marko ACS Catalysis, Vol. 6, Issue 4 https://doi.org/10.1021/acscatal.5b02850	journal	February 2016
ω-Transaminases for the synthesis of non-racemic α-chiral primary amines Koszelewski, Dominik; Tauber, Katharina; Faber, Kurt Trends in Biotechnology, Vol. 28, Issue 6 https://doi.org/10.1016/j.tibtech.2010.03.003	journal	June 2010
Dispelling the Myths--Biocatalysis in Industrial Synthesis Schoemaker, H. E. Science, Vol. 299, Issue 5613 https://doi.org/10.1126/science.1079237	journal	March 2003
Electrochemical regeneration of NADH on a glassy carbon electrode surface: The influence of electrolysis potential Ali, Irshad; Soomro, Bebul; Omanovic, Sasha Electrochemistry Communications, Vol. 13, Issue 6 https://doi.org/10.1016/j.elecom.2011.03.010	journal	June 2011
Electrochemical evaluation of the reaction rate between methyl viologen mediator and diaphorase enzyme for the electrocatalytic reduction of NAD+ and digital simulation for its voltammetric responses Kim, Sohyoung; Yun, Sei-Eok; Kang, Chan Journal of Electroanalytical Chemistry, Vol. 465, Issue 2 https://doi.org/10.1016/S0022-0728(99)00074-1	journal	April 1999
Electrochemical reduction of NAD+ on a polycrystalline gold electrode Damian, Alexis; Omanovic, Sasha Journal of Molecular Catalysis A: Chemical, Vol. 253, Issue 1-2 https://doi.org/10.1016/j.molcata.2006.03.020	journal	July 2006
Non-enzymatic regeneration of nicotinamide and flavin cofactors for monooxygenase catalysis Hollmann, F.; Hofstetter, K.; Schmid, A. Trends in Biotechnology, Vol. 24, Issue 4 https://doi.org/10.1016/j.tibtech.2006.02.003	journal	April 2006
Investigation of Photoelectrochemical Corrosion of Semiconductors Frese, K. W. Journal of The Electrochemical Society, Vol. 128, Issue 9 https://doi.org/10.1149/1.2127770	journal	January 1981
Direct reduction of NAD+ by electrochemical procedure and application of the regenerated NADH to enzyme reaction Yun, Se-Eok; Taya, Masahito; Tone, Setsuji Biotechnology Letters, Vol. 16, Issue 10 https://doi.org/10.1007/BF01022402	journal	October 1994
A kinetic study of NAD+ reduction on a ruthenium modified glassy carbon electrode Man, Felise; Omanovic, Sasha Journal of Electroanalytical Chemistry, Vol. 568 https://doi.org/10.1016/j.jelechem.2004.02.006	journal	July 2004
Interactive Adsorption Behavior of NAD ⁺ at a Gold Electrode Surface Damian, Alexis; Omanovic, Sasha Langmuir, Vol. 23, Issue 6 https://doi.org/10.1021/la062385q	journal	March 2007
Direct electrochemical regeneration of NADH from NAD+ using cholesterol-modified gold amalgam electrode Baik, Sang Ho; Kang, Chan; Jeon, II Cheol Biotechnology Techniques, Vol. 13, Issue 1, p. 1-5 https://doi.org/10.1023/A:1008865212773	journal	January 1999
Electrochemical NADH regeneration and electroenzymatic CO2 reduction on Cu nanorods/glassy carbon electrode prepared by cyclic deposition Kim, Seung-Han; Chung, Gui-Yung; Kim, Seong-Hoon Electrochimica Acta, Vol. 210 https://doi.org/10.1016/j.electacta.2016.06.007	journal	August 2016
Recent developments in pyridine nucleotide regeneration van der Donk, Wilfred A.; Zhao, Huimin Current Opinion in Biotechnology, Vol. 14, Issue 4 https://doi.org/10.1016/S0958-1669(03)00094-6	journal	August 2003
Direct electrocatalytic reduction of coenzyme NAD+ to enzymatically-active 1,4-NADH employing an iridium/ruthenium-oxide electrode Ullah, Nehar; Ali, Irshad; Omanovic, Sasha Materials Chemistry and Physics, Vol. 149-150 https://doi.org/10.1016/j.matchemphys.2014.10.038	journal	January 2015
A lactate dehydrogenase amperometric pyruvate electrode exploiting direct detection of NAD+ at a poly(3-methylthiophene):poly(phenol red) modified platinum surface Warriner, K.; Higson, S.; Vadgama, P. Materials Science and Engineering: C, Vol. 5, Issue 2 https://doi.org/10.1016/S0928-4931(97)00067-2	journal	December 1997
Biocatalytic Reductions: From Lab Curiosity to “First Choice” De Wildeman, Stefaan M. A.; Sonke, Theo; Schoemaker, Hans E. Accounts of Chemical Research, Vol. 40, Issue 12 https://doi.org/10.1021/ar7001073	journal	October 2007
Electrochemical regeneration of nicotinamide cofactor using a polypyrrole rhodium bis-terpyridine modified electrode Beley, Marc; Collin, Jean-Paul Journal of Molecular Catalysis, Vol. 79, Issue 1-3 https://doi.org/10.1016/0304-5102(93)85096-C	journal	February 1993
Regeneration of cofactors for use in biocatalysis Zhao, Huimin; van der Donk, Wilfred A. Current Opinion in Biotechnology, Vol. 14, Issue 6 https://doi.org/10.1016/j.copbio.2003.09.007	journal	December 2003
Electroreduction of NAD+ to enzymatically active NADH at poly(neutral red) modified electrodes Karyakin, Arkady A.; Bobrova, Oksana A.; Karyakina, Elena E. Journal of Electroanalytical Chemistry, Vol. 399, Issue 1-2 https://doi.org/10.1016/0022-0728(95)04300-4	journal	December 1995
Selective Solar-Driven Reduction of CO ₂ to Methanol Using a Catalyzed p-GaP Based Photoelectrochemical Cell Barton, Emily E.; Rampulla, David M.; Bocarsly, Andrew B. Journal of the American Chemical Society, Vol. 130, Issue 20 https://doi.org/10.1021/ja0776327	journal	May 2008
Biocatalytic Redox Reactions for Organic Synthesis: Nonconventional Regeneration Methods Hollmann, Frank; Arends, Isabel W. C. E.; Buehler, Katja ChemCatChem, Vol. 2, Issue 7 https://doi.org/10.1002/cctc.201000069	journal	June 2010
The Reversible Hydrogen Electrode: Potential-Dependent Activation Energies over Platinum from Quantum Theory Cai, Yu; Anderson, Alfred B. The Journal of Physical Chemistry B, Vol. 108, Issue 28 https://doi.org/10.1021/jp037126d	journal	July 2004
Electrocatalytic behavior of glassy carbon electrode modified with ruthenium nanoparticles and ruthenium film Rahman, Gul; Mian, Shabeer Ahmad; Shah, Anwar ul Haq Ali Journal of Applied Electrochemistry, Vol. 46, Issue 4 https://doi.org/10.1007/s10800-016-0937-1	journal	February 2016
Rhodium-Coordinated Poly(arylene-ethynylene)- alt -Poly(arylene-vinylene) Copolymer Acting as Photocatalyst for Visible-Light-Powered NAD ⁺ /NADH Reduction Oppelt, Kerstin T.; Gasiorowski, Jacek; Egbe, Daniel Ayuk Mbi Journal of the American Chemical Society, Vol. 136, Issue 36 https://doi.org/10.1021/ja506060u	journal	September 2014
Semiconductor electrodes. 24. Behavior of photoelectrochemical cells based on p-type gallium arsenide in aqueous solutions Fan, Fu Ren F.; Bard, Allen J. Journal of the American Chemical Society, Vol. 102, Issue 11 https://doi.org/10.1021/ja00531a002	journal	May 1980
Diaphorase-Viologen Conjugates as Bioelectrocatalysts for NADH Regeneration Dinh, Thu Huong; Lee, Sang Cheon; Hou, Chen Yuan Journal of The Electrochemical Society, Vol. 163, Issue 6 https://doi.org/10.1149/2.1211606jes	journal	January 2016
Using a One-Electron Shuttle for the Multielectron Reduction of CO₂ to Methanol: Kinetic, Mechanistic, and Structural Insights Barton Cole, Emily; Lakkaraju, Prasad S.; Rampulla, David M. Journal of the American Chemical Society, Vol. 132, Issue 33, p. 11539-11551 https://doi.org/10.1021/ja1023496	journal	August 2010
Electrocatalytic Carbon Dioxide Activation: The Rate-Determining Step of Pyridinium-Catalyzed CO₂ Reduction Morris, Amanda J.; McGibbon, Robert T.; Bocarsly, Andrew B. ChemSusChem, Vol. 4, Issue 2, p. 191-196 https://doi.org/10.1002/cssc.201000379	journal	February 2011
Photoelectrocatalysis and electrocatalysis on p-silicon Szklarczyk, M.; Bockris, J. O'M. The Journal of Physical Chemistry, Vol. 88, Issue 9 https://doi.org/10.1021/j150653a028	journal	April 1984
Theory of Stationary Electrode Polarography. Single Scan and Cyclic Methods Applied to Reversible, Irreversible, and Kinetic Systems. Nicholson, R. S.; Shain, Irving Analytical Chemistry, Vol. 36, Issue 4, p. 706-723 https://doi.org/10.1021/ac60210a007	journal	April 1964
Experiment and theory of ‘transparent’ metal films Porter, John D.; Heller, Adam; Aspnes, David E. Nature, Vol. 313, Issue 6004 https://doi.org/10.1038/313664a0	journal	February 1985
On the assignment of the redox peaks observed in phosphate and phosphite solutions at a Pt electrode Takehara, Kô; Ide, Y.; Nakazato, Tetsuya Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, Vol. 293, Issue 1-2 https://doi.org/10.1016/0022-0728(90)80072-E	journal	October 1990

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Title: Photoelectrochemical NADH Regeneration using Pt-Modified p -GaAs Semiconductor Electrodes

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