Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

Stagno, J. R.; Liu, Y.; Bhandari, Y. R.; Conrad, C. E.; Panja, S.; Swain, M.; Fan, L.; Nelson, G.; Li, C.; Wendel, D. R.; White, T. A.; Coe, J. D.; Wiedorn, M. O.; Knoska, J.; Oberthuer, D.; Tuckey, R. A.; Yu, P.; Dyba, M.; Tarasov, S. G.; Weierstall, U.; Grant, T. D.; Schwieters, C. D.; Zhang, J.; Ferre-D’Amare, A. R.; Fromme, P.; Draper, D. E.; Liang, M.; Hunter, M. S.; Boutet, S.; Tan, K.; Zuo, X.; Ji, X.; Barty, A.; Zatsepin, N. A.; Chapman, H. N.; Spence, J. C. H.; Woodson, S. A.; Wang, Y. -X.

doi:10.1038/nature20599

Title: Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

Journal Article · Mon Nov 14 00:00:00 EST 2016 · Nature (London)

DOI:https://doi.org/10.1038/nature20599· OSTI ID:1371547

Stagno, J. R. ^[1]; Liu, Y. ^[1]; Bhandari, Y. R. ^[1]; Conrad, C. E. ^[2]; Panja, S. ^[3]; Swain, M. ^[1]; Fan, L. ^[1]; Nelson, G. ^[2]; Li, C. ^[2]; Wendel, D. R. ^[1]; White, T. A. ^[4]; Coe, J. D. ^[2]; Wiedorn, M. O. ^[5]; Knoska, J. ^[5]; Oberthuer, D. ^[4]; Tuckey, R. A. ^[1]; Yu, P. ^[1]; Dyba, M. ^[1]; Tarasov, S. G. ^[1]; Weierstall, U. ^[2] more »

National Cancer Institute, Frederick, MD (United States)
Arizona State Univ., Tempe, AZ (United States)
Johns Hopkins Univ., Baltimore, MD (United States)
Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)
Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Univ. of Hamburg, Hamburg (Germany)
Hauptmann-Woodward Medical Research Institute, Buffalo, NY (United States)
National Institutes of Health, Bethesda, MD (United States)
SLAC National Accelerator Lab., Menlo Park, CA (United States)
Argonne National Lab. (ANL), Argonne, IL (United States)

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Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States); SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Biological and Environmental Research (BER); European Research Council (ERC)

Grant/Contract Number:: AC02-06CH11357; AC02-76SF00515

OSTI ID:: 1371547

Alternate ID(s):: OSTI ID: 1353097

Journal Information:: Nature (London), Vol. 541, Issue 7636; ISSN 0028-0836

Publisher:: Nature Publishing GroupCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 180 works

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Perspective: Opportunities for ultrafast science at SwissFEL Abela, Rafael; Beaud, Paul; Van Bokhoven, Jeroen A. AIP Publishing https://doi.org/10.7892/boris.114739	text	January 2017
Megahertz serial crystallography Wiedorn, Max O.; Oberthür, Dominik; Bean, Richard Nature Communications, Vol. 9, Issue 1 https://doi.org/10.1038/s41467-018-06156-7	journal	October 2018
X-ray free electron laser: opportunities for drug discovery Cheng, Robert K. Y.; Abela, Rafael; Hennig, Michael Essays in Biochemistry, Vol. 61, Issue 5 https://doi.org/10.1042/ebc20170031	journal	November 2017
A Cryo-EM Grid Preparation Device for Time-Resolved Structural Studies Kontziampasis, Dimitrios; Klebl, David P.; Iadanza, Matthew G. IUCrJ https://doi.org/10.1101/563254	journal	March 2019
Journey to the center of the protein: allostery from multitemperature multiconformer X-ray crystallography Keedy, Daniel A. Acta Crystallographica Section D Structural Biology, Vol. 75, Issue 2 https://doi.org/10.1107/s2059798318017941	journal	January 2019
Strategies for sample delivery for femtosecond crystallography Martiel, Isabelle; Müller-Werkmeister, Henrike M.; Cohen, Aina E. International Union of Crystallography (IUCr) https://doi.org/10.1107/s2059798318017953/ba5296sup1.pdf	text	January 2019
Membrane protein megahertz crystallography at the European XFEL Gisriel, Christopher; Coe, Jesse; Letrun, Romain Nature Publishing Group UK https://doi.org/10.15480/882.2506	text	January 2019
Structural enzymology using X-ray free electron lasers Kupitz, Christopher; Olmos, Jose L.; Holl, Mark Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2016-06266	text	January 2017
Structure-factor amplitude reconstruction from serial femtosecond crystallography of two-dimensional membrane-protein crystals Casadei, Cecilia M.; Nass, Karol; Barty, Anton Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2018-04823	text	January 2019
The Single Particles, Clusters and Biomolecules and Serial Femtosecond Crystallography instrument of the European XFEL: initial installation Mancuso, Adrian P.; Aquila, Andrew; Batchelor, Lewis Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2019-01957	text	January 2019
On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies Lieske, Julia; Cerv, Maximilian; Kreida, Stefan Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2019-02620	text	January 2019
Perspective: Opportunities for ultrafast science at SwissFEL Abela, Rafael; Beaud, Paul; van Bokhoven, Jeroen A. Structural Dynamics, Vol. 4, Issue 6 https://doi.org/10.1063/1.4997222	journal	November 2017
Allosteric Mechanism of the V. vulnificus Adenine Riboswitch Resolved by Four-dimensional Chemical Mapping Tian, Siqi; Kladwang, Wipapat; Das, Rhiju https://doi.org/10.1101/157412	journal	February 2018
Structure of the 30S ribosomal decoding complex at ambient temperature Dao, E. Han; Poitevin, Frédéric; Sierra, Raymond G. RNA, Vol. 24, Issue 12 https://doi.org/10.1261/rna.067660.118	journal	August 2018
Co-crystal structure of the Fusobacterium ulcerans ZTP riboswitch using an X-ray free-electron laser Jones, Christopher; Tran, Brandon; Conrad, Chelsie Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2019-02740	text	January 2019
Rapid Sample Delivery for Megahertz Serial Crystallography at X-ray FELs Wiedorn, Max O.; Awel, Salah; Morgan, Andrew J. Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2018-02209	text	January 2018
Ultracompact 3D microfluidics for time-resolved structural biology Knoska, Juraj; Adriano, Luigi; Awel, Salah Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2020-00623	text	January 2020
Serial Femtosecond X-Ray Diffraction of HIV-1 Gag MA-IP6 Microcrystals at Ambient Temperature I. Ciftci, Halil; G. Sierra, Raymond; Yoon, Chun International Journal of Molecular Sciences, Vol. 20, Issue 7 https://doi.org/10.3390/ijms20071675	journal	April 2019
Perspective: Opportunities for ultrafast science at SwissFEL Abela, Rafael; Beaud, Paul; Van Bokhoven, Jeroen A. ETH Zurich https://doi.org/10.3929/ethz-b-000231826	text	January 2017
Short-wavelength free-electron laser sources and science: a review Seddon, E. A.; Clarke, J. A.; Dunning, D. J. Reports on Progress in Physics, Vol. 80, Issue 11 https://doi.org/10.1088/1361-6633/aa7cca	journal	October 2017
Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography Olmos, Jose L.; Pandey, Suraj; Martin-Garcia, Jose M. BMC Biology, Vol. 16, Issue 1 https://doi.org/10.1186/s12915-018-0524-5	journal	May 2018
Megahertz serial crystallography Wiedorn, Max Oliver; Oberthür, Dominik; Bean, Richard Nature Publishing Group UK https://doi.org/10.15480/882.2175	text	January 2018
MHz Data Collection of a Microcrystalline mMxture of Different Jack Bean Proteins Grünbein, Marie Luise; Bielecki, Johan; Gorel, Alexander Deutsches Elektronen-Synchrotron, DESY, Hamburg https://doi.org/10.3204/pubdb-2020-00843	text	January 2019
RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview Šponer, Jiří; Bussi, Giovanni; Krepl, Miroslav Chemical Reviews, Vol. 118, Issue 8 https://doi.org/10.1021/acs.chemrev.7b00427	journal	January 2018
Single-Molecule Fluorescence Reveals Commonalities and Distinctions among Natural and in Vitro-Selected RNA Tertiary Motifs in a Multistep Folding Pathway Bonilla, Steve; Limouse, Charles; Bisaria, Namita Journal of the American Chemical Society, Vol. 139, Issue 51 https://doi.org/10.1021/jacs.7b08870	journal	November 2017
Graph-theoretical analysis for energy landscape reveals the organization of state transitions in the resting-state human cerebral cortex Kang, Jiyoung; Pae, Chongwon; Park, Hae-Jeong PLOS ONE, Vol. 14, Issue 9 https://doi.org/10.1371/journal.pone.0222161	journal	September 2019
Macromolecular Nanocrystal Structural Analysis with Electron and X-Rays: A Comparative Review Khakurel, Krishna P.; Angelov, Borislav; Andreasson, Jakob Molecules, Vol. 24, Issue 19 https://doi.org/10.3390/molecules24193490	journal	September 2019
A tool for visualizing protein motions in time-resolved crystallography Cecilia, Wickstrand,; Gergely, Katona,; Takanori, Nakane, ETH Zurich https://doi.org/10.3929/ethz-b-000409850	text	January 2020

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