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Title: Determining significant endpoints for ecological risk analyses. 1998 annual progress report

Technical Report ·
DOI:https://doi.org/10.2172/13598· OSTI ID:13598
; ;  [1];  [2]; ;  [3]
  1. Univ. of Georgia, Aiken, SC (US). Savannah River Ecology Lab.
  2. Univ. of Puerto Rico, San Juan (PR)
  3. Colorado State Univ., Fort Collins, CO (US)

'The goal of this report is to establish a protocol for assessing risks to non-human populations exposed to environmental stresses typically found on many DOE sites. The authors think that they can achieve this by using novel biological dosimeters in controlled, manipulative dose/effects experiments, and by coupling changes in metabolic rates and energy allocation patterns to meaningful population response variables (such as age-specific survivorship, reproductive output, age at maturity and longevity). This research is needed to determine the relevancy of sublethal cellular damage to the performance of individuals and populations exposed to chronic, low-level radiation, and radiation with concomitant exposure to chemicals. They believe that a scientifically defensible endpoint for measuring ecological risks can only be determined once its understood the extent to which molecular damage from contaminant exposure is detrimental at the individual and population levels of biological organization. The experimental facility will allow them to develop a credible assessment tool for appraising ecological risks, and to evaluate the effects of radionuclide/chemical synergisms on non-human species. This report summarizes work completed midway of a 3-year project that began in November 1996. Emphasis to date has centered on three areas: (1) developing a molecular probe to measure stable chromosomal aberrations known as reciprocal translocations, (2) constructing an irradiation facility where the statistical power inherent in replicated mesocosms can be used to address the response of non-human organisms to exposures from low levels of radiation and metal contaminants, and (3) quantifying responses of organisms living in contaminated mesocosms and field sites.'

Research Organization:
Univ. of Georgia, Savannah River Ecology Lab., Aiken, SC (US)
Sponsoring Organization:
USDOE Office of Environmental Management (EM), Office of Science and Risk Policy
OSTI ID:
13598
Report Number(s):
EMSP-55410-98; ON: DE00013598
Country of Publication:
United States
Language:
English