U.S. Department of EnergyOffice of Scientific and Technical Information
Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy
Abstract
Following a 6-h inhalation exposure to aerosolized 20 and 110 nm diameter silver nanoparticles, lung tissues from rats were investigated with X-ray absorption spectroscopy, which can identify the chemical state of silver species. Lung tissues were processed immediately after sacrifice of the animals at 0, 1, 3, and 7 days post exposure and the samples were stored in an inert and low-temperature environment until measured. We found that it is critical to follow a proper processing, storage and measurement protocol; otherwise only silver oxides are detected after inhalation even for the larger nanoparticles. The results of X-ray absorption spectroscopy measurements taken in air at 85 K suggest that the dominating silver species in all the postexposure lung tissues were metallic silver, not silver oxide, or solvated silver cations. The results further indicate that the silver nanoparticles in the tissues were transformed from the original nanoparticles to other forms of metallic silver nanomaterials and the rate of this transformation depended on the size of the original nanoparticles. Furthermore, we found that 20 nm diameter silver nanoparticles were significantly modified after aerosolization and 6-h inhalation/deposition, whereas larger, 110 nm diameter nanoparticles were largely unchanged. Over the seven-day postexposure period the smaller 20more »
- Authors:
-
- Univ. of California, Davis, CA (United States)
- Publication Date:
- Research Org.:
- Univ. of California, Davis, CA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1346164
- Grant/Contract Number:
- AC02-76SF00515
- Resource Type:
- Journal Article: Accepted Manuscript
- Journal Name:
- Journal of Physical Chemistry. A, Molecules, Spectroscopy, Kinetics, Environment, and General Theory
- Additional Journal Information:
- Journal Volume: 119; Journal Issue: 2; Journal ID: ISSN 1089-5639
- Publisher:
- American Chemical Society
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 36 MATERIALS SCIENCE
Citation Formats
Davidson, R. Andrew, Anderson, Donald S., Van Winkle, Laura S., Pinkerton, Kent E., and Guo, T. Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy. United States: N. p., 2014.
Web. doi:10.1021/jp510103m.
Davidson, R. Andrew, Anderson, Donald S., Van Winkle, Laura S., Pinkerton, Kent E., & Guo, T. Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy. United States. https://doi.org/10.1021/jp510103m
Davidson, R. Andrew, Anderson, Donald S., Van Winkle, Laura S., Pinkerton, Kent E., and Guo, T. 2014.
"Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy". United States. https://doi.org/10.1021/jp510103m. https://www.osti.gov/servlets/purl/1346164.
@article{osti_1346164,
title = {Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy},
author = {Davidson, R. Andrew and Anderson, Donald S. and Van Winkle, Laura S. and Pinkerton, Kent E. and Guo, T.},
abstractNote = {Following a 6-h inhalation exposure to aerosolized 20 and 110 nm diameter silver nanoparticles, lung tissues from rats were investigated with X-ray absorption spectroscopy, which can identify the chemical state of silver species. Lung tissues were processed immediately after sacrifice of the animals at 0, 1, 3, and 7 days post exposure and the samples were stored in an inert and low-temperature environment until measured. We found that it is critical to follow a proper processing, storage and measurement protocol; otherwise only silver oxides are detected after inhalation even for the larger nanoparticles. The results of X-ray absorption spectroscopy measurements taken in air at 85 K suggest that the dominating silver species in all the postexposure lung tissues were metallic silver, not silver oxide, or solvated silver cations. The results further indicate that the silver nanoparticles in the tissues were transformed from the original nanoparticles to other forms of metallic silver nanomaterials and the rate of this transformation depended on the size of the original nanoparticles. Furthermore, we found that 20 nm diameter silver nanoparticles were significantly modified after aerosolization and 6-h inhalation/deposition, whereas larger, 110 nm diameter nanoparticles were largely unchanged. Over the seven-day postexposure period the smaller 20 nm silver nanoparticles underwent less change in the lung tissue than the larger 110 nm silver nanoparticles. In contrast, silica-coated gold nanoparticles did not undergo any modification processes and remained as the initial nanoparticles throughout the 7-day study period.},
doi = {10.1021/jp510103m},
url = {https://www.osti.gov/biblio/1346164},
journal = {Journal of Physical Chemistry. A, Molecules, Spectroscopy, Kinetics, Environment, and General Theory},
issn = {1089-5639},
number = 2,
volume = 119,
place = {United States},
year = {Tue Dec 16 00:00:00 EST 2014},
month = {Tue Dec 16 00:00:00 EST 2014}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 23 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Nanotechnology as a therapeutic tool to combat microbial resistance
journal, November 2013
- Pelgrift, Robert Y.; Friedman, Adam J.
- Advanced Drug Delivery Reviews, Vol. 65, Issue 13-14
The antimicrobial efficacy of sustained release silver–carbene complex-loaded l-tyrosine polyphosphate nanoparticles: Characterization, in vitro and in vivo studies
journal, August 2009
- Hindi, Khadijah M.; Ditto, Andrew J.; Panzner, Matthew J.
- Biomaterials, Vol. 30, Issue 22
Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria
journal, July 2004
- Sondi, Ivan; Salopek-Sondi, Branka
- Journal of Colloid and Interface Science, Vol. 275, Issue 1
Nanosilver: Weighing the Risks and Benefits
journal, July 2013
- Seltenrich, Nate
- Environmental Health Perspectives, Vol. 121, Issue 7
Environmental and Human Health Risks of Aerosolized Silver Nanoparticles
journal, July 2010
- Quadros, Marina E.; Marr, Linsey C.
- Journal of the Air & Waste Management Association, Vol. 60, Issue 7
Twenty-Eight-Day Inhalation Toxicity Study of Silver Nanoparticles in Sprague-Dawley Rats
journal, January 2007
- Ji, Jun Ho; Jung, Jae Hee; Kim, Sang Soo
- Inhalation Toxicology, Vol. 19, Issue 10
Toxicity of silver nanoparticles in zebrafish models
journal, May 2008
- Asharani, P. V.; Lian Wu, Yi; Gong, Zhiyuan
- Nanotechnology, Vol. 19, Issue 25
Toxicity Assessments of Multisized Gold and Silver Nanoparticles in Zebrafish Embryos
journal, August 2009
- Bar-Ilan, Ofek; Albrecht, Ralph M.; Fako, Valerie E.
- Small, Vol. 5, Issue 16
Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells
journal, September 2009
- Kim, Soohee; Choi, Ji Eun; Choi, Jinhee
- Toxicology in Vitro, Vol. 23, Issue 6
In vitro toxicity assessment of silver nanoparticles in Chang liver cells and J-774 macrophages
journal, July 2010
- Garza-Ocañas, L.; Ramirez-Cabrera, M.; Zanatta-Calderon, M. T.
- Toxicology Letters, Vol. 196
Acute inhalation toxicity of silver nanoparticles
journal, September 2010
- Sung, Jae Hyuck; Ji, Jun Ho; Song, Kyung Seuk
- Toxicology and Industrial Health, Vol. 27, Issue 2, p. 149-154
Estimation of human equivalent exposure from rat inhalation toxicity study of silver nanoparticles using multi-path particle dosimetry model
journal, January 2012
- Ji, Jun Ho; Yu, Il Je
- Toxicology Research, Vol. 1, Issue 3
Distribution, Elimination, and Toxicity of Silver Nanoparticles and Silver Ions in Rats after 28-Day Oral Exposure
journal, July 2012
- van der Zande, Meike; Vandebriel, Rob J.; Van Doren, Elke
- ACS Nano, Vol. 6, Issue 8
The toxicity of silver nanoparticles to zebrafish embryos increases through sewage treatment processes
journal, August 2013
- Muth-Köhne, Elke; Sonnack, Laura; Schlich, Karsten
- Ecotoxicology, Vol. 22, Issue 8
Toxicity of Silver Nanoparticles in Macrophages
journal, February 2013
- Pratsinis, Anna; Hervella, Pablo; Leroux, Jean-Christophe
- Small, Vol. 9, Issue 15
Oral toxicity of silver ions, silver nanoparticles and colloidal silver – A review
journal, February 2014
- Hadrup, Niels; Lam, Henrik R.
- Regulatory Toxicology and Pharmacology, Vol. 68, Issue 1
Toxicity Mechanisms in Escherichia coli Vary for Silver Nanoparticles and Differ from Ionic Silver
journal, December 2013
- Ivask, Angela; ElBadawy, Amro; Kaweeteerawat, Chitrada
- ACS Nano, Vol. 8, Issue 1
Silver nanoparticles and silver nitrate induce high toxicity to Pseudokirchneriella subcapitata, Daphnia magna and Danio rerio
journal, January 2014
- Ribeiro, Fabianne; Gallego-Urrea, Julián Alberto; Jurkschat, Kerstin
- Science of The Total Environment, Vol. 466-467
Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential
journal, August 2013
- Wang, Xiang; Ji, Zhaoxia; Chang, Chong Hyun
- Small, Vol. 10, Issue 2
The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern?
journal, February 2007
- Chopra, Ian
- Journal of Antimicrobial Chemotherapy, Vol. 59, Issue 4
Toxicity of Silver Nanoparticles Increases during Storage Because of Slow Dissolution under Release of Silver Ions
journal, August 2010
- Kittler, S.; Greulich, C.; Diendorf, J.
- Chemistry of Materials, Vol. 22, Issue 16
Genotoxicity and toxicity of silver nanoparticles and silver ions
journal, August 2011
- Beer, C.; Foldbjerg, R.; Dang, D. A.
- Toxicology Letters, Vol. 205
Toxicity of silver nanoparticles—Nanoparticle or silver ion?
journal, February 2012
- Beer, Christiane; Foldbjerg, Rasmus; Hayashi, Yuya
- Toxicology Letters, Vol. 208, Issue 3
Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications
journal, June 2013
- Reidy, Bogumiła; Haase, Andrea; Luch, Andreas
- Materials, Vol. 6, Issue 6
A comprehensive evaluation of the enzymatic and nonenzymatic antioxidant systems in childhood asthma
journal, July 2008
- Sackesen, Cansin; Ercan, Hulya; Dizdar, Evrim
- Journal of Allergy and Clinical Immunology, Vol. 122, Issue 1
Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage.
journal, April 2003
- Li, Ning; Sioutas, Constantinos; Cho, Arthur
- Environmental Health Perspectives, Vol. 111, Issue 4
Environmental Transformations of Silver Nanoparticles: Impact on Stability and Toxicity
journal, February 2012
- Levard, Clément; Hotze, E. Matt; Lowry, Gregory V.
- Environmental Science & Technology, Vol. 46, Issue 13
The dissolution and biological effects of silver nanoparticles in biological media
journal, January 2014
- Loza, K.; Diendorf, J.; Sengstock, C.
- Journal of Materials Chemistry B, Vol. 2, Issue 12
Chemical Transformations of Nanosilver in Biological Environments
journal, October 2012
- Liu, Jingyu; Wang, Zhongying; Liu, Frances D.
- ACS Nano, Vol. 6, Issue 11
Generation of Metal Nanoparticles from Silver and Copper Objects: Nanoparticle Dynamics on Surfaces and Potential Sources of Nanoparticles in the Environment
journal, October 2011
- Glover, Richard D.; Miller, John M.; Hutchison, James E.
- ACS Nano, Vol. 5, Issue 11
An Example of X-ray Nanochemistry: SERS Investigation of Polymerization Enhanced by Nanostructures under X-ray Irradiation
journal, October 2012
- Davidson, R. Andrew; Guo, Ting
- The Journal of Physical Chemistry Letters, Vol. 3, Issue 22
Release of Silver from Nanotechnology-Based Consumer Products for Children
journal, August 2013
- Quadros, Marina E.; Pierson, Raymond; Tulve, Nicolle S.
- Environmental Science & Technology, Vol. 47, Issue 15
Analysis of Adsorption and Binding Behaviors of Silver Nanoparticles onto a Pyridyl-Terminated Surface Using XPS and AFM
journal, November 2011
- Fukuda, Nobuko; Ishida, Naoyuki; Nomura, Kenichi
- Langmuir, Vol. 27, Issue 21
Effect of surface carbon coating on sintering of silver nanoparticles: in situ TEM observations
journal, January 2014
- Asoro, M. A.; Kovar, D.; Ferreira, P. J.
- Chem. Commun., Vol. 50, Issue 37
X-ray absorption spectroscopy of biological samples. A tutorial
journal, January 2012
- Ortega, Richard; Carmona, Asuncion; Llorens, Isabelle
- Journal of Analytical Atomic Spectrometry, Vol. 27, Issue 12
Role of base in the formation of silver nanoparticles synthesized using sodium acrylate as a dual reducing and encapsulating agent
journal, January 2011
- Nishimura, Shun; Mott, Derrick; Takagaki, Atsushi
- Physical Chemistry Chemical Physics, Vol. 13, Issue 20
An EXAFS study of photographic development in thermographic films
journal, June 2007
- Blanton, T. N.; Whitcomb, D. R.; Misture, S. T.
- Powder Diffraction, Vol. 22, Issue 2
Formation of Ag clusters in zeolite X studied by in situ EXAFS and infrared spectroscopy
journal, March 2013
- Miyanaga, Takafumi; Suzuki, Yushi; Matsumoto, Naoyuki
- Microporous and Mesoporous Materials, Vol. 168
XAFS study of copper and silver nanoparticles in glazes of medieval middle-east lustreware (10th–13th century)
journal, March 2006
- Padovani, S.; Puzzovio, D.; Sada, C.
- Applied Physics A, Vol. 83, Issue 4
Synthesis and Surface Modification of Highly Monodispersed, Spherical Gold Nanoparticles of 50−200 nm
journal, December 2009
- Perrault, Steven D.; Chan, Warren C. W.
- Journal of the American Chemical Society, Vol. 131, Issue 47
Turkevich Method for Gold Nanoparticle Synthesis Revisited
journal, August 2006
- Kimling, J.; Maier, M.; Okenve, B.
- The Journal of Physical Chemistry B, Vol. 110, Issue 32
An improved apparatus for acute inhalation exposure of rodents to radioactive aerosols
journal, October 1973
- Raabe, Otto G.; Bennick, Jerry E.; Light, Max E.
- Toxicology and Applied Pharmacology, Vol. 26, Issue 2
Influence of Particle Size on Persistence and Clearance of Aerosolized Silver Nanoparticles in the Rat Lung
journal, January 2015
- Anderson, Donald S.; Patchin, Esther S.; Silva, Rona M.
- Toxicological Sciences, Vol. 144, Issue 2
Surface Segregation in Ni/Co Bimetallic Nanoparticles Produced in Single-Walled Carbon Nanotube Synthesis
journal, June 2002
- Cheng, Guangjun; Guo, Ting
- The Journal of Physical Chemistry B, Vol. 106, Issue 23
SIXPack a Graphical User Interface for XAS Analysis Using IFEFFIT
journal, January 2005
- Webb, S. M.
- Physica Scripta
Study of local environment of Ag in Ag/CeO2 catalyst by EXAFS
journal, August 2002
- Sarode, P. R.; Priolkar, K. R.; Bera, Parthasarathi
- Materials Research Bulletin, Vol. 37, Issue 9
Estimation of mean size and shape of small metal particles by EXAFS
journal, January 1999
- Jentys, Andreas
- Physical Chemistry Chemical Physics, Vol. 1, Issue 17
X-ray Absorption Near-Edge Structure and X-ray Photoelectron Spectroscopy Studies of Interfacial Charge Transfer in Gold–Silver–Gold Double-Shell Nanoparticles
journal, February 2012
- Nishimura, Shun; Dao, Anh Thi Ngoc; Mott, Derrick
- The Journal of Physical Chemistry C, Vol. 116, Issue 7
Toxicity Assessments of Multisized Gold and Silver Nanoparticles in Zebrafish Embryos
journal, August 2009
- Bar-Ilan, Ofek; Albrecht, Ralph M.; Fako, Valerie E.
- Small, Vol. 5, Issue 16
Toxicity of Silver Nanoparticles in Macrophages
journal, February 2013
- Pratsinis, Anna; Hervella, Pablo; Leroux, Jean-Christophe
- Small, Vol. 9, Issue 15
Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential
journal, August 2013
- Wang, Xiang; Ji, Zhaoxia; Chang, Chong Hyun
- Small, Vol. 10, Issue 2
The toxicity of silver nanoparticles to zebrafish embryos increases through sewage treatment processes
journal, August 2013
- Muth-Köhne, Elke; Sonnack, Laura; Schlich, Karsten
- Ecotoxicology, Vol. 22, Issue 8
Nanotechnology as a therapeutic tool to combat microbial resistance
journal, November 2013
- Pelgrift, Robert Y.; Friedman, Adam J.
- Advanced Drug Delivery Reviews, Vol. 65, Issue 13-14
The antimicrobial efficacy of sustained release silver–carbene complex-loaded l-tyrosine polyphosphate nanoparticles: Characterization, in vitro and in vivo studies
journal, August 2009
- Hindi, Khadijah M.; Ditto, Andrew J.; Panzner, Matthew J.
- Biomaterials, Vol. 30, Issue 22
Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria
journal, July 2004
- Sondi, Ivan; Salopek-Sondi, Branka
- Journal of Colloid and Interface Science, Vol. 275, Issue 1
Formation of Ag clusters in zeolite X studied by in situ EXAFS and infrared spectroscopy
journal, March 2013
- Miyanaga, Takafumi; Suzuki, Yushi; Matsumoto, Naoyuki
- Microporous and Mesoporous Materials, Vol. 168
Silver nanoparticles and silver nitrate induce high toxicity to Pseudokirchneriella subcapitata, Daphnia magna and Danio rerio
journal, January 2014
- Ribeiro, Fabianne; Gallego-Urrea, Julián Alberto; Jurkschat, Kerstin
- Science of The Total Environment, Vol. 466-467
Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells
journal, September 2009
- Kim, Soohee; Choi, Ji Eun; Choi, Jinhee
- Toxicology in Vitro, Vol. 23, Issue 6
Toxicity of silver nanoparticles—Nanoparticle or silver ion?
journal, February 2012
- Beer, Christiane; Foldbjerg, Rasmus; Hayashi, Yuya
- Toxicology Letters, Vol. 208, Issue 3
Toxicity of Silver Nanoparticles Increases during Storage Because of Slow Dissolution under Release of Silver Ions
journal, August 2010
- Kittler, S.; Greulich, C.; Diendorf, J.
- Chemistry of Materials, Vol. 22, Issue 16
Environmental Transformations of Silver Nanoparticles: Impact on Stability and Toxicity
journal, February 2012
- Levard, Clément; Hotze, E. Matt; Lowry, Gregory V.
- Environmental Science & Technology, Vol. 46, Issue 13
Synthesis and Surface Modification of Highly Monodispersed, Spherical Gold Nanoparticles of 50−200 nm
journal, August 2010
- Perrault, Steven D.; Chan, Warren C. W.
- Journal of the American Chemical Society, Vol. 132, Issue 33
Turkevich Method for Gold Nanoparticle Synthesis Revisited
journal, August 2006
- Kimling, J.; Maier, M.; Okenve, B.
- The Journal of Physical Chemistry B, Vol. 110, Issue 32
Analysis of Adsorption and Binding Behaviors of Silver Nanoparticles onto a Pyridyl-Terminated Surface Using XPS and AFM
journal, November 2011
- Fukuda, Nobuko; Ishida, Naoyuki; Nomura, Kenichi
- Langmuir, Vol. 27, Issue 21
Meditations on the Ubiquity and Mutability of Nano-Sized Materials in the Environment
journal, October 2011
- Wiesner, Mark R.; Lowry, Gregory V.; Casman, Elizabeth
- ACS Nano, Vol. 5, Issue 11
Distribution, Elimination, and Toxicity of Silver Nanoparticles and Silver Ions in Rats after 28-Day Oral Exposure
journal, July 2012
- van der Zande, Meike; Vandebriel, Rob J.; Van Doren, Elke
- ACS Nano, Vol. 6, Issue 8
Chemical Transformations of Nanosilver in Biological Environments
journal, October 2012
- Liu, Jingyu; Wang, Zhongying; Liu, Frances D.
- ACS Nano, Vol. 6, Issue 11
Toxicity Mechanisms in Escherichia coli Vary for Silver Nanoparticles and Differ from Ionic Silver
journal, December 2013
- Ivask, Angela; ElBadawy, Amro; Kaweeteerawat, Chitrada
- ACS Nano, Vol. 8, Issue 1
Estimation of mean size and shape of small metal particles by EXAFS
journal, January 1999
- Jentys, Andreas
- Physical Chemistry Chemical Physics, Vol. 1, Issue 17
Role of base in the formation of silver nanoparticles synthesized using sodium acrylate as a dual reducing and encapsulating agent
journal, January 2011
- Nishimura, Shun; Mott, Derrick; Takagaki, Atsushi
- Physical Chemistry Chemical Physics, Vol. 13, Issue 20
The dissolution and biological effects of silver nanoparticles in biological media
journal, January 2014
- Loza, K.; Diendorf, J.; Sengstock, C.
- Journal of Materials Chemistry B, Vol. 2, Issue 12
Characterization of nanoscale silver particles in glasses by temperature-dependent EXAFS spectroscopy
journal, May 2000
- Dubiel, M.; Brunsch, S.; Tröger, L.
- Journal of Physics: Condensed Matter, Vol. 12, Issue 22
X-Ray Absorption Near-Edge Structure (XANES) Spectroscopy Study of the Interaction of Silver Ions with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli
journal, August 2013
- Bovenkamp, Gudrun Lisa; Zanzen, Ulrike; Krishna, Katla Sai
- Applied and Environmental Microbiology, Vol. 79, Issue 20
Antibacterial Activity and Mechanism of Action of the Silver Ion in Staphylococcus aureus and Escherichia coli
journal, February 2008
- Jung, Woo Kyung; Koo, Hye Cheong; Kim, Ki Woo
- Applied and Environmental Microbiology, Vol. 74, Issue 7
Acute inhalation toxicity of silver nanoparticles
journal, September 2010
- Sung, Jae Hyuck; Ji, Jun Ho; Song, Kyung Seuk
- Toxicology and Industrial Health, Vol. 27, Issue 2, p. 149-154
Novel lanthanide-labeled metal oxide nanoparticles improve the measurement of in vivo clearance and translocation
journal, January 2013
- Abid, Aamir D.; Anderson, Donald S.; Das, Gautom K.
- Particle and Fibre Toxicology, Vol. 10, Issue 1
Effect of different drying techniques on flowability characteristics and chemical properties of natural carbohydrate-protein Gum from durian fruit seed
journal, January 2013
- Mirhosseini, Hamed; Amid, Bahareh Tabatabaee
- Chemistry Central Journal, Vol. 7, Issue 1
Nanosilver: Weighing the Risks and Benefits
journal, July 2013
- Seltenrich, Nate
- Environmental Health Perspectives, Vol. 121, Issue 7
Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage.
journal, April 2003
- Li, Ning; Sioutas, Constantinos; Cho, Arthur
- Environmental Health Perspectives, Vol. 111, Issue 4
Silver nanoparticles modify VEGF signaling pathway and mucus hypersecretion in allergic airway inflammation
journal, March 2012
- Park, Ji Won
- International Journal of Nanomedicine
Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo
journal, October 2013
- Xiang, Dongxi; Zheng, Cong-long; Zheng, Yang
- International Journal of Nanomedicine
Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition
journal, September 2014
- Anderson, Donald S.; Silva, Rona M.; Lee, Danielle
- Nanotoxicology, Vol. 9, Issue 5
Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications
journal, June 2013
- Reidy, Bogumiła; Haase, Andrea; Luch, Andreas
- Materials, Vol. 6, Issue 6
Works referencing / citing this record:
Corrosion processes of triangular silver nanoparticles compared to bulk silver
journal, February 2016
- Keast, V. J.; Myles, T. A.; Shahcheraghi, N.
- Journal of Nanoparticle Research, Vol. 18, Issue 2
Influence of Particle Size on Persistence and Clearance of Aerosolized Silver Nanoparticles in the Rat Lung
journal, January 2015
- Anderson, Donald S.; Patchin, Esther S.; Silva, Rona M.
- Toxicological Sciences, Vol. 144, Issue 2
Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain
journal, December 2016
- Patchin, Esther Shin; Anderson, Donald S.; Silva, Rona M.
- Environmental Health Perspectives, Vol. 124, Issue 12
Silver nanoparticles: Electron transfer, reactive oxygen species, oxidative stress, beneficial and toxicological effects. Mini review: AGNP BENEFICIAL AND TOXICOLOGICAL EFFECTS
journal, June 2018
- Flores-López, Lucía Z.; Espinoza-Gómez, Heriberto; Somanathan, Ratnasamy
- Journal of Applied Toxicology, Vol. 39, Issue 1
Metal-organic framework patterns and membranes with heterogeneous pores for flow-assisted switchable separations
journal, September 2018
- Jeong, Guan-Young; Singh, Ajay K.; Kim, Min-Gyu
- Nature Communications, Vol. 9, Issue 1
Aerosolized Silver Nanoparticles in the Rat Lung and Pulmonary Responses over Time
journal, February 2016
- Silva, Rona M.; Anderson, Donald S.; Peake, Janice
- Toxicologic Pathology, Vol. 44, Issue 5
Metal-organic framework patterns and membranes with heterogeneous pores for flow-assisted switchable separations
journal, September 2018
- Jeong, Guan-Young; Singh, Ajay K.; Kim, Min-Gyu
- Nature Communications, Vol. 9, Issue 1
Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain
journal, December 2016
- Patchin, Esther Shin; Anderson, Donald S.; Silva, Rona M.
- Environmental Health Perspectives, Vol. 124, Issue 12