DHAD variants and methods of screening

Kelly, Kristen J.; Ye, Rick W.

Title: DHAD variants and methods of screening

Patent · Tue Feb 28 00:00:00 EST 2017

OSTI ID:1345383

Kelly, Kristen J.; Ye, Rick W.

Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.

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Research Organization:: Butamax Advanced Biofuels LLC Wilmington, DE (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AR0000006

Assignee:: Butamax Advanced Biofuels LLC

Patent Number(s):: 9,580,705

Application Number:: 14/207,823

OSTI ID:: 1345383

Resource Relation:: Patent File Date: 2014 Mar 13

Country of Publication:: United States

Language:: English

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