Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice

Fan, Quli; Cheng, Kai; Yang, Zhen; Zhang, Ruiping; Yang, Min; Hu, Xiang; Ma, Xiaowei; Bu, Lihong; Lu, Xiaomei; Xiong, Xiaoxing; Huang, Wei; Zhao, Heng; Cheng, Zhen

doi:10.1002/adma.201402972

Title: Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice

Journal Article · Thu Nov 06 00:00:00 EST 2014 · Advanced Materials

DOI:https://doi.org/10.1002/adma.201402972· OSTI ID:1342723

Fan, Quli ^[1]; Cheng, Kai ^[2]; Yang, Zhen ^[3]; Zhang, Ruiping ^[4]; Yang, Min ^[5]; Hu, Xiang ^[2]; Ma, Xiaowei ^[2]; Bu, Lihong ^[2]; Lu, Xiaomei ^[3]; Xiong, Xiaoxing ^[2]; Huang, Wei ^[3]; Zhao, Heng ^[2]; Cheng, Zhen ^[2]

Nanjing Univ. of Posts & Telecommunications, Nanjing (China); Stanford Univ., Stanford, CA (United States)
Stanford Univ., Stanford, CA (United States)
Nanjing Univ. of Posts & Telecommunications, Nanjing (China)
Stanford Univ., Stanford, CA (United States); First Hospital of Shanxi Medical Univ., Taiyuan (China)
Stanford Univ., Stanford, CA (United States); Jiangsu Institute of Nuclear Medicine, Wuxi (China)

In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. In this paper, perylene-3,4,9,10-tetracarboxylic diiimide-based near-infrared-absorptive organic nanoparticles are reported as an efficient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect

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Research Organization:: Stanford Univ., CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Biological and Environmental Research (BER)

Grant/Contract Number:: SC0008397

OSTI ID:: 1342723

Journal Information:: Advanced Materials, Vol. 27, Issue 5; ISSN 0935-9648

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 195 works

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