Modified host cells with efflux pumps

Dunlop, Mary J.; Keasling, Jay D.; Mukhopadhyay, Aindrila

Title: Modified host cells with efflux pumps

Patent · Tue Aug 30 00:00:00 EDT 2016

OSTI ID:1312679

Dunlop, Mary J.; Keasling, Jay D.; Mukhopadhyay, Aindrila

The present invention provides for a modified host cell comprising a heterologous expression of an efflux pump capable of transporting an organic molecule out of the host cell wherein the organic molecule at a sufficiently high concentration reduces the growth rate of or is lethal to the host cell.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 9,428,726

Application Number:: 13/115,925

OSTI ID:: 1312679

Resource Relation:: Patent File Date: 2011 May 25

Country of Publication:: United States

Language:: English

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