Hydroxyethyl cellulose matrix applied to serial crystallography
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journal
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April 2017 |
Well-based crystallization of lipidic cubic phase microcrystals for serial X-ray crystallography experiments
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journal
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October 2019 |
Evaluation of serial crystallographic structure determination within megahertz pulse trains
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journal
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November 2019 |
The β-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors
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journal
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April 2016 |
GPCR-SAS: A web application for statistical analyses on G protein-coupled receptors sequences
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journal
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July 2018 |
Biased signalling: from simple switches to allosteric microprocessors
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journal
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January 2018 |
Critical role of the finger loop in arrestin binding to the receptors
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journal
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March 2019 |
The XFEL Protein Crystallography: Developments and Perspectives
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journal
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July 2019 |
A complex structure of arrestin-2 bound to a G protein-coupled receptor
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journal
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October 2019 |
G-Protein–Coupled Receptors in Heart Disease
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journal
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August 2018 |
Biological single-particle imaging using XFELs – towards the next resolution revolution
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text
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January 2018 |
Functional competence of a partially engaged GPCR–β-arrestin complex
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journal
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November 2016 |
GPCR structure and function relationship: identification of a biased apelin receptor mutant
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journal
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December 2018 |
Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor
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journal
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September 2019 |
Structural biology of G protein‐coupled receptor signaling complexes
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journal
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December 2018 |
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody
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text
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January 2017 |
Molecular Mechanisms of GPCR Signaling: A Structural Perspective
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journal
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November 2017 |
Molecular mechanism of modulating arrestin conformation by GPCR phosphorylation
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journal
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June 2018 |
Development of an antibody fragment that stabilizes GPCR/G-protein complexes
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journal
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September 2018 |
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody
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journal
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July 2017 |
Melanopsin Carboxy-terminus Phosphorylation Plasticity and Bulk Negative Charge, not Strict Site Specificity, Achieves Phototransduction Deactivation
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journal
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January 2020 |
Structural biology and structure–function relationships of membrane proteins
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journal
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December 2018 |
Allosteric modulation model of the mu opioid receptor by herkinorin, a potent not alkaloidal agonist
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journal
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March 2017 |
Update on melatonin receptors: IUPHAR Review 20: Melatonin receptors
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journal
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August 2016 |
Structural Biology and Structure–Function Relationships of Membrane Proteins
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journal
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March 2021 |
Megahertz serial crystallography
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text
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January 2018 |
X-ray free electron laser: opportunities for drug discovery
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journal
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November 2017 |
Structure-Function Relationships of the Follicle-Stimulating Hormone Receptor
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journal
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November 2018 |
Differential Phosphorylation Provides a Switch to Control How α-Arrestin Rod1 Down-regulates Mating Pheromone Response in Saccharomyces cerevisiae
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journal
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May 2016 |
Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors
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journal
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November 2016 |
Peptide mini-scaffold facilitates JNK3 activation in cells
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journal
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February 2016 |
An online resource for GPCR structure determination and analysis
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journal
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January 2019 |
Viscosity-adjustable grease matrices for serial nanocrystallography
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journal
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January 2020 |
β-arrestin–biased signaling through the β 2 -adrenergic receptor promotes cardiomyocyte contraction
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journal
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June 2016 |
Structural basis of ligand interaction with atypical chemokine receptor 3
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journal
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January 2017 |
Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation
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journal
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August 2016 |
Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure
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journal
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August 2017 |
GPCRdb: an information system for G protein-coupled receptors
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journal
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December 2016 |
Endosomal PTH Receptor Signaling Through cAMP and Its Consequence for Human Medicine
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book
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January 2017 |
Structural basis of arrestin-3 activation and signaling
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journal
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November 2017 |
X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex
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text
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January 2016 |
A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity
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journal
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February 2020 |
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist
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journal
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March 2018 |
In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures
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journal
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January 2016 |
G s protein peptidomimetics as allosteric modulators of the β 2 -adrenergic receptor
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journal
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January 2018 |
A complex structure of arrestin-2 bound to a G protein-coupled receptor
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journal
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November 2019 |
New approaches towards the understanding of integral membrane proteins: A structural perspective on G protein-coupled receptors: Structural Perspective on G Protein-Coupled Receptors
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journal
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June 2017 |
Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications
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journal
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March 2016 |
An Overview of the Top Ten Detergents Used for Membrane Protein Crystallization
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journal
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July 2017 |
Cryo-EM structure of the native rhodopsin dimer in nanodiscs
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journal
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August 2019 |
Crystal structure of rhodopsin in complex with a mini-G o sheds light on the principles of G protein selectivity
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journal
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September 2018 |
Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor
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journal
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February 2020 |
Structural insights into G-protein-coupled receptor allostery
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journal
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July 2018 |
Current and Future Challenges in GPCR Drug Discovery
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book
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November 2017 |
GPCRdb: the G protein-coupled receptor database - an introduction: GPCRdb: the GPCR database
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journal
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June 2016 |
Structure and Activation Mechanism of GPCRs
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book
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January 2019 |
Short-wavelength free-electron laser sources and science: a review
|
text
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January 2017 |
Arrestin-1 engineering facilitates complex stabilization with native rhodopsin
|
text
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January 2019 |
Intracellular allosteric antagonism of the CCR9 receptor
|
journal
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December 2016 |
Biological single-particle imaging using XFELs – towards the next resolution revolution
|
journal
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October 2018 |
Combinatorial allosteric modulation of agonist response in a self-interacting G-protein coupled receptor
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journal
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January 2020 |
Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals
|
text
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January 2018 |
Common activation mechanism of class A GPCRs
|
journal
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December 2019 |
Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity
|
text
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January 2018 |
Molecular mechanism of GPCR-mediated arrestin activation
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journal
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May 2018 |
Common and biased signaling pathways of the chemokine receptor CCR7 elicited by its ligands CCL19 and CCL21 in leukocytes
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journal
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January 2016 |
Molecular assembly of rhodopsin with G protein-coupled receptor kinases
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journal
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May 2017 |
Chemokine Receptor Crystal Structures: What Can Be Learned from Them?
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journal
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July 2019 |
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
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text
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January 2017 |
Molecular dynamics simulation of the follicle-stimulating hormone receptor. Understanding the conformational dynamics of receptor variants at positions N680 and D408 from in silico analysis
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journal
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November 2018 |
Structural insights into melatonin receptors
|
journal
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November 2019 |
Fixed-target serial oscillation crystallography at room temperature
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text
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January 2019 |
Allosteric modulation as a unifying mechanism for receptor function and regulation
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journal
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September 2017 |
Arrestin-mediated signaling: Is there a controversy?
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journal
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December 2018 |
Sequence, Structure, and Expression of Opsins in the Monochromatic Stomatopod Squilla empusa
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journal
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April 2018 |
GPCRdb: an information system for G protein-coupled receptors
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journal
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November 2015 |
Cell-Translocation Mechanisms of CPPs
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book
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June 2019 |
GPCR Signaling Regulation: The Role of GRKs and Arrestins
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journal
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February 2019 |
Serial Femtosecond Crystallography
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journal
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November 2015 |
GPCR signaling: conformational activation of arrestins
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journal
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July 2018 |
Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors
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journal
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November 2019 |
Short-wavelength free-electron laser sources and science: a review
|
journal
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October 2017 |
Computational design of G Protein-Coupled Receptor allosteric signal transductions
|
journal
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December 2019 |
Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes
|
journal
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July 2017 |
X-ray free-electron laser: opportunities for drug discovery
|
journal
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July 2018 |
Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence
|
journal
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April 2019 |
Microfluidics: From crystallization to serial time-resolved crystallography
|
journal
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May 2017 |
Sample delivery for serial crystallography at free-electron lasers and synchrotrons
|
journal
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January 2019 |
Lack of beta-arrestin signaling in the absence of active G proteins
|
journal
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January 2018 |
Molecular Mechanism of Biased Signaling in a Prototypical G-protein-coupled Receptor
|
journal
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February 2020 |
Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain
|
journal
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February 2018 |
Recent Advances in Ultrafast Structural Techniques
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journal
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April 2019 |
C-edge loops of arrestin function as a membrane anchor
|
text
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January 2017 |
Nanodiscs for structural and functional studies of membrane proteins
|
journal
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June 2016 |
Accurate determination of segmented X-ray detector geometry
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text
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January 2015 |
CCR5 adopts three homodimeric conformations that control cell surface delivery
|
journal
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May 2018 |
The Multiple Waves of Cannabinoid 1 Receptor Signaling
|
journal
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June 2016 |
Evaluation of serial crystallographic structure determination within megahertz pulse trains
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text
|
January 2019 |
Common activation mechanism of class A GPCRs.
|
journalarticle
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January 2019 |
Molecular pharmacology of metabotropic receptors targeted by neuropsychiatric drugs
|
journal
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July 2019 |
X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex
|
journal
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April 2016 |
In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization of the active complex
|
text
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January 2019 |
Hitchhiking on the heptahelical highway: structure and function of 7TM receptor complexes
|
journal
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April 2016 |
Fixed-target serial oscillation crystallography at room temperature
|
text
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January 2019 |
Structural basis for selectivity and diversity in angiotensin II receptors
|
journal
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April 2017 |
A comparative study of branched and linear mannitol-based amphiphiles on membrane protein stability
|
journal
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January 2018 |
Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3–mediated chemokine scavenging
|
journal
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November 2017 |
Protein crystal screening and characterization for serial femtosecond nanocrystallography
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journal
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May 2016 |
An outlook on using serial femtosecond crystallography in drug discovery
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journal
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May 2019 |
Structure and dynamics of GPCR signaling complexes
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journal
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January 2018 |
Arrestins: structural disorder creates rich functionality
|
journal
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February 2018 |
State-Dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo -Mimetic Membranes
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posted_content
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July 2018 |
Arrestin-1 engineering facilitates complex stabilization with native rhodopsin
|
journal
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January 2019 |
Toward G protein-coupled receptor structure-based drug design using X-ray lasers
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journal
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October 2019 |
Structures of Non-rhodopsin GPCRs Elucidated Through X-Ray Crystallography
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book
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January 2017 |
Single-particle cryo-EM—How did it get here and where will it go
|
journal
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August 2018 |
Watching proteins function with time-resolved x-ray crystallography
|
journal
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August 2017 |
Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin
|
journal
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August 2018 |
The Diverse Roles of Arrestin Scaffolds in G Protein–Coupled Receptor Signaling
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journal
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April 2017 |
Vitamin E-based glycoside amphiphiles for membrane protein structural studies
|
journal
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January 2018 |
Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR
|
journal
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January 2018 |
Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex
|
journal
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December 2016 |
Hologenomic adaptations underlying the evolution of sanguivory in the common vampire bat
|
journal
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February 2018 |
The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer
|
journal
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August 2016 |
Endo-lysosomal sorting of G-protein-coupled receptors by ubiquitin: Diverse pathways for G-protein-coupled receptor destruction and beyond
|
journal
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November 2018 |
Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography
|
text
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January 2016 |
Time-resolved serial femtosecond crystallography at the European XFEL
|
journal
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November 2019 |
Asymmetric maltose neopentyl glycol amphiphiles for a membrane protein study: effect of detergent asymmetricity on protein stability
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journal
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January 2019 |
Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex
|
journal
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November 2019 |
Structure of an allosteric modulator bound to the CB1 cannabinoid receptor
|
journal
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October 2019 |
G protein–coupled receptor kinases (GRKs) orchestrate biased agonism at the β 2 -adrenergic receptor
|
journal
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August 2018 |
Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography
|
text
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January 2016 |
Pharmacogenomics of GPCR Drug Targets
|
journal
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January 2018 |
Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7
|
journal
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August 2019 |
Drug Binding Poses Relate Structure with Efficacy in the μ Opioid Receptor
|
journal
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June 2017 |
Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity
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journal
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December 2017 |
Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation
|
journal
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March 2019 |
New views on phototransduction from atomic force microscopy and single molecule force spectroscopy on native rods
|
journal
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September 2017 |
Rethinking the Origin of Primates by Reconstructing Their Diel Activity Patterns Using Genetics and Morphology
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journal
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September 2017 |
The orientation and stability of the GPCR-Arrestin complex in a lipid bilayer
|
journal
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December 2017 |
A host dTMP-bound structure of T4 phage dCMP hydroxymethylase mutant using an X-ray free electron laser
|
journal
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November 2019 |
Structure and dynamics of a constitutively active neurotensin receptor
|
journal
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December 2016 |
Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites
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journal
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September 2017 |
Seeing β-arrestin in action: The role of β-arrestins in Histamine 1 Receptor signaling
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journal
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September 2019 |
Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography
|
journal
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August 2016 |
Native phasing of x-ray free-electron laser data for a G protein–coupled receptor
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journal
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September 2016 |
Molecular Defects of the Disease-Causing Human Arrestin-1 C147F Mutant
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journal
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January 2018 |
Improving virtual screening of G protein-coupled receptors via ligand-directed modeling
|
journal
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November 2017 |
Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity
|
journal
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October 2015 |
Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation
|
journal
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April 2020 |
Structural Studies of G Protein-Coupled Receptors
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journal
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October 2015 |
Endocrinology and the brain: corticotropin-releasing hormone signaling
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journal
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August 2017 |
Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor.
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journalarticle
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January 2017 |
Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1
|
journal
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June 2018 |
Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
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journal
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September 2016 |
Recent Progress in Understanding the Conformational Mechanism of Heterotrimeric G Protein Activation
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journal
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January 2017 |
Evaluating experimental and theoretical measures of protein conformational dynamics
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dissertation
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January 2016 |