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Title: Atom probe tomographic mapping directly reveals the atomic distribution of phosphorus in resin embedded ferritin

Journal Article · · Scientific Reports
DOI:https://doi.org/10.1038/srep22321· OSTI ID:1243203
 [1];  [1];  [1];  [1];  [2];  [1];  [1]
  1. Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  2. Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Qatar Environment and Energy Research Institute, Doha (Qatar)
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In this study, we report the atomic-scale analysis of biological interfaces using atom probe tomography. Embedding the protein ferritin in an organic polymer resin lacking nitrogen provided chemical contrast to visualize atomic distributions and distinguish organic-organic and organic-inorganic interfaces. The sample preparation method can be directly extended to further enhance the study of biological, organic and inorganic nanomaterials relevant to health, energy or the environment.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
Grant/Contract Number:
AC05-76RL01830
OSTI ID:
1243203
Report Number(s):
PNNL-SA-112512; 48671
Journal Information:
Scientific Reports, Vol. 6; ISSN 2045-2322
Publisher:
Nature Publishing GroupCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 50 works
Citation information provided by
Web of Science

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Cited By (11)

Polymer on Top: Current Limits and Future Perspectives of Quantitatively Evaluating Surface Grafting journal March 2018
Direct Imaging of Dopant and Impurity Distributions in 2D MoS 2 journal January 2020
Biomineralization at Titanium Revealed by Correlative 4D Tomographic and Spectroscopic Methods journal May 2018
Ionic Dependence of Gelatin Hydrogel Architecture Explored Using Small and Very Small Angle Neutron Scattering Technique journal May 2018
Atom Probe Tomography for 3D Structural and Chemical Analysis of Individual Proteins journal May 2019
A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography journal December 2018
Nanometer-Scale Chemistry of a Calcite Biomineralization Template: Implications for Skeletal Composition and Nucleation journal October 2016
Visualizing the iron atom exchange front in the Fe(II)-catalyzed recrystallization of goethite by atom probe tomography journal February 2019
An environmental transfer hub for multimodal atom probe tomography journal May 2017
Preliminary Data on the Nanoscale Chemical Characterization of the Inter-Crystalline Organic Matrix of a Calcium Carbonate Biomineral journal May 2018
An environmental transfer hub for multimodal atom probe tomography text January 2017

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