skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Modular radiochemistry synthesis system

Patent ·
OSTI ID:1230010

A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures. The modular chemical production system is assembled from modules which can each include operating condition sensors and controllers configured for monitoring and controlling the individual modules and the assembled system from a remote position. Other modules include, but are not limited to a Reagent Storage and Delivery Module, a Cartridge Purification Module, a Microwave Reaction Module, an External QC/Analysis/Purification Interface Module, an Aliquotting Module, an F-18 Drying Module, a Concentration Module, a Radiation Counting Module, and a Capillary Reactor Module.

Research Organization:
Univ. of California, Oakland, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-06ER64249
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Patent Number(s):
9,211,520
Application Number:
14/582,885
OSTI ID:
1230010
Resource Relation:
Patent File Date: 2014 Dec 24
Country of Publication:
United States
Language:
English

References (10)

Apparatus and process for preparing radioisotope-labeled reagent patent June 1998
Microwave assisted chemical processes patent October 1999
Perfusion hyperthermia treatment system and method patent July 2002
Method, System, and Sub-System, for Processing a Chemical Reaction patent-application February 2004
Device for synthesis of radiopharmaceutical products patent-application February 2004
System and method for synthesis of molecular imaging probes including FDG patent-application December 2004
Method and system for forming a film of material using plasmon assisted chemical reactions patent-application October 2005
Microwave Heating System patent-application August 2006
System and Method for Processing Chemical Substances, Computer Program for Controlling Such System, and a Corresponding Computer-Readable Storage Medium patent-application September 2008
A retrospective on the automation of laboratory synthetic chemistry journal October 1992

Similar Records

Modular radiochemistry synthesis system
Patent · Tue Nov 01 00:00:00 EDT 2016 · OSTI ID:1230010

Modular radiochemistry synthesis system
Patent · Tue Feb 10 00:00:00 EST 2015 · OSTI ID:1230010

Reactor vessel sealing plug
Patent · Tue Nov 25 00:00:00 EST 1986 · OSTI ID:1230010