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Title: Accurate and rapid micromixer for integrated microfluidic devices

Patent ·
OSTI ID:1221397

The invention may provide a microfluidic mixer having a droplet generator and a droplet mixer in selective fluid connection with the droplet generator. The droplet generator comprises first and second fluid chambers that are structured to be filled with respective first and second fluids that can each be held in isolation for a selectable period of time. The first and second fluid chambers are further structured to be reconfigured into a single combined chamber to allow the first and second fluids in the first and second fluid chambers to come into fluid contact with each other in the combined chamber for a selectable period of time prior to being brought into the droplet mixer.

Research Organization:
Univ. of California, Oakland, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-06ER64249
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
9,138,700
Application Number:
12/863,276
OSTI ID:
1221397
Resource Relation:
Patent File Date: 2009 Jan 21
Country of Publication:
United States
Language:
English

References (21)

Miniaturized genetic analysis systems and methods patent January 2001
Method of manipulating a gas bubble in a microfluidic device patent December 2001
Valves and pumps for microfluidic systems and method for making microfluidic systems patent July 2004
Devices and methods for fluid mixing patent July 2005
Microfabricated elastomeric valve and pump systems patent May 2006
Combination valve and regulation for use with pressurized gas cylinders, particularly oxygen cylinders patent October 2006
Process for filling microfluidic channels patent December 2006
Microfluidic method and structure with an elastomeric gas-permeable gasket patent January 2011
Microfluidic chemical reaction circuits patent June 2012
Method and apparatus for the mechanical actuation of valves in fluidic devices patent July 2013
System and Method for Interfacing with a Microfluidic Chip patent-application June 2008
Rapid Mixing Using Two-Phase Hydraulic Focusing in Microchannels journal March 2005
Micromixers—a review on passive and active mixing principles journal April 2005
Micromixing of Miscible Liquids in Segmented Gas−Liquid Flow journal February 2005
Reactions in Droplets in Microfluidic Channels journal November 2006
Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channels journal December 2003
Millisecond Kinetics on a Microfluidic Chip Using Nanoliters of Reagents journal November 2003
A Microfabricated Rotary Pump journal January 2001
From The Cover: Systematic investigation of protein phase behavior with a microfluidic formulator journal September 2004
Microfluidics: Fluid physics at the nanoliter scale journal October 2005
High-Throughput DNA Droplet Assays Using Picoliter Reactor Volumes journal September 2007

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