Piperazine-based nucleic acid analogs
Patent
·
OSTI ID:1175200
A novel nucleoside analog is disclosed which comprises a piperazine ring in the place of the ring ribose or deoxyribose sugar. Monomers utilizing a broad variety of nucleobases are disclosed, as well as oligomers comprising the monomers disclosed herein linked by a variety of linkages, including amide, phosphonamide, and sulfonamide linkages. A method of synthesizing the nucleoside analogs is also disclosed.
- Research Organization:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- W-7405-ENG-36
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Number(s):
- 6,841,675
- Application Number:
- 10/171,073
- OSTI ID:
- 1175200
- Country of Publication:
- United States
- Language:
- English
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