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Title: Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream

Patent ·
OSTI ID:1175027

A microfluidic device for forming and/or dispensing minute volume segments of a material is described. In accordance with one aspect of the present invention, a microfluidic device and method is provided for spatially confining the material in a focusing element. The device is also capable of segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-00OR22725
Assignee:
UT-Battelle, LLC (TN)
Patent Number(s):
6,790,328
Application Number:
09/759,590
OSTI ID:
1175027
Country of Publication:
United States
Language:
English

References (3)

Electrokinetic Flow in a Narrow Cylindrical Capillary journal November 1965
Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip journal August 1993
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane) journal October 1998