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Title: Biomarkers for lymphoma

Patent ·
OSTI ID:1154935

A biomarker, method, test kit, and diagnostic system for detecting the presence of lymphoma in a person are disclosed. The lymphoma may be Hodgkin's lymphoma or non-Hodgkin's lymphoma. The person may be a high-risk subject. In one embodiment, a plasma sample from a person is obtained. The level of at least one protein listed in Table S3 in the plasma sample is measured. The level of at least one protein in the plasma sample is compared with the level in a normal or healthy subject. The lymphoma is diagnosed based upon the level of the at least one protein in the plasma sample in comparison to the normal or healthy level.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RLO1830
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Number(s):
8,822,164
Application Number:
13/690,073
OSTI ID:
1154935
Country of Publication:
United States
Language:
English

References (8)

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Method for Differentially Quantifying Naturally Processed HLA-Restricted Peptides for Cancer, Autoimmune and Infectious Diseases Immunotherapy Development patent-application October 2011
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Different prognostic factors for survival in acute and lymphomatous adult T-cell leukemia/lymphoma journal March 2011
Serum beta 2 microglobulin and C-reactive protein in the monitoring of lymphomas findings in a multicenter study and experience in selected patients journal January 1980