Numerical Optimization Algorithms and Software for Systems Biology
The basic aims of this work are: to develop reliable algorithms for solving optimization problems involving large stoi- chiometric matrices; to investigate cyclic dependency between metabolic and macromolecular biosynthetic networks; and to quantify the significance of thermodynamic constraints on prokaryotic metabolism.
- Research Organization:
- Stanford Univ., CA (United States)
- Sponsoring Organization:
- USDOE; USDOE SC Office of Advanced Scientific Computing Research (SC-21)
- DOE Contract Number:
- SC0002009
- OSTI ID:
- 1107780
- Report Number(s):
- DOE-STANFORD-02009
- Country of Publication:
- United States
- Language:
- English
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