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Title: Multidimensional bioseparation with modular microfluidics

Patent ·
OSTI ID:1093279

A multidimensional chemical separation and analysis system is described including a prototyping platform and modular microfluidic components capable of rapid and convenient assembly, alteration and disassembly of numerous candidate separation systems. Partial or total computer control of the separation system is possible. Single or multiple alternative processing trains can be tested, optimized and/or run in parallel. Examples related to the separation and analysis of human bodily fluids are given.

Research Organization:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC04-94AL85000
Assignee:
Sandia Corporation (Albuquerque, NM)
Patent Number(s):
8,518,346
Application Number:
12/157,601
OSTI ID:
1093279
Country of Publication:
United States
Language:
English

References (8)

Chemical processing microsystems comprising parallel flow microreactors and methods for using same patent June 2004
Scalable continuous production system patent October 2008
Apparatus and method for concurrent chemical synthesis patent July 2001
Microliter scale solid phase extraction devices patent-application July 2006
Microfluidics Prototyping Platform and Components patent-application August 2006
A List of Candidate Cancer Biomarkers for Targeted Proteomics journal January 2006
Computational prediction of proteotypic peptides for quantitative proteomics journal December 2006
Concepts and comparisons in multidimensional separation journal May 1987