Probes for anionic cell surface detection
Abstract
Embodiments of the present invention are generally directed to compositions comprising a class of molecular probes for detecting the presence of anionic cell surfaces. Embodiments include compositions that are enriched for these compositions and preparations, particularly preparations suitable for use as laboratory/clinical reagents and diagnostic indicators, either alone or as part of a kit. An embodiment of the invention provides for a highly selective agent useful in the discernment and identification of dead or dying cells, such as apoptotic cells, in a relatively calcium-free environment. An embodiment of the invention provides a selective agent for the identification of bacteria in a mixed population of bacterial cells and nonbacterial cells.
- Inventors:
- Publication Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1083461
- Patent Number(s):
- 8,389,223
- Application Number:
- 12/874,689
- Assignee:
- University of Notre Dame du Lac (Notre Dame, IN)
- DOE Contract Number:
- AC04-94AL8500
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Smith, Bradley D. Probes for anionic cell surface detection. United States: N. p., 2013.
Web.
Smith, Bradley D. Probes for anionic cell surface detection. United States.
Smith, Bradley D. 2013.
"Probes for anionic cell surface detection". United States. https://www.osti.gov/servlets/purl/1083461.
@article{osti_1083461,
title = {Probes for anionic cell surface detection},
author = {Smith, Bradley D.},
abstractNote = {Embodiments of the present invention are generally directed to compositions comprising a class of molecular probes for detecting the presence of anionic cell surfaces. Embodiments include compositions that are enriched for these compositions and preparations, particularly preparations suitable for use as laboratory/clinical reagents and diagnostic indicators, either alone or as part of a kit. An embodiment of the invention provides for a highly selective agent useful in the discernment and identification of dead or dying cells, such as apoptotic cells, in a relatively calcium-free environment. An embodiment of the invention provides a selective agent for the identification of bacteria in a mixed population of bacterial cells and nonbacterial cells.},
doi = {},
url = {https://www.osti.gov/biblio/1083461},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 05 00:00:00 EST 2013},
month = {Tue Mar 05 00:00:00 EST 2013}
}
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