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Title: Multi-layer micro/nanofluid devices with bio-nanovalves

Patent ·
OSTI ID:1082938

A user-friendly multi-layer micro/nanofluidic flow device and micro/nano fabrication process are provided for numerous uses. The multi-layer micro/nanofluidic flow device can comprise: a substrate, such as indium tin oxide coated glass (ITO glass); a conductive layer of ferroelectric material, preferably comprising a PZT layer of lead zirconate titanate (PZT) positioned on the substrate; electrodes connected to the conductive layer; a nanofluidics layer positioned on the conductive layer and defining nanochannels; a microfluidics layer positioned upon the nanofluidics layer and defining microchannels; and biomolecular nanovalves providing bio-nanovalves which are moveable from a closed position to an open position to control fluid flow at a nanoscale.

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
ACO2-06CH11357
Assignee:
UChicago Argonne, LLC (Argonne, IL)
Patent Number(s):
8,343,425
Application Number:
12/391,486
OSTI ID:
1082938
Country of Publication:
United States
Language:
English

References (7)

Ferroelectric-Specific Peptides as Building Blocks for Bio-Inorganic Devices journal January 2006
Electrokinetic concentration device and methods of use thereof patent-application August 2006
A Light-Actuated Nanovalve Derived from a Channel Protein journal July 2005
Integration of Biomolecules with Inorganic Ferroelectrics: A Novel Approach to Nanoscale Devices journal January 2006
Design and fabrication of a multilayer micro-/nanofluidic device with an electrically driven nanovalve
  • Li, Hao; Ocola, Leonidas E.; Auciello, Orlando
  • Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films, Vol. 26, Issue 4 https://doi.org/10.1116/1.2936227
journal July 2008
Hybrid three-dimensional nanofluidic/microfluidic devices using molecular gates journal January 2003
Multilayer microfluidic-nanofluidic device patent-application September 2007

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