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Title: Methods for monitoring multiple gene expression

Patent ·
OSTI ID:1044062

The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing Trichoderma reesei ESTs or SSH clones, or a combination thereof. The present invention also relates to computer readable media and substrates containing such array features for monitoring expression of a plurality of genes in filamentous fungal cells.

Research Organization:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC36-98GO10337
Assignee:
Novozymes, Inc. (Davis, CA)
Patent Number(s):
8,168,768
Application Number:
12/133,642
OSTI ID:
1044062
Country of Publication:
United States
Language:
English

References (8)

Differential Expression of the Vegetative and Spore-Bound Hydrophobins of Trichoderma Reesei Cloning and Characterization of the Hfb2 Gene journal September 1997
Technology for microarray analysis of gene expression journal December 1998
Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes journal March 1999
Elucidation of the Metabolic Fate of Glucose in the Filamentous Fungus Trichoderma reesei Using Expressed Sequence Tag (EST) Analysis and cDNA Microarrays journal February 2002
The Transcriptional Program of Sporulation in Budding Yeast journal October 1998
Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries. journal June 1996
Towards Arabidopsis genome analysis: monitoring expression profiles of 1400 genes using cDNA microarrays: Expression profiles of 1400 Arabidopsis genes journal September 1998
Shotgun DNA microarrays and stage-specific gene expression in Plasmodium falciparum malaria journal January 2000