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Title: Unnatural reactive amino acid genetic code additions

Patent ·
OSTI ID:1026521
 [1];  [2];  [3];  [4];  [1]
  1. La Jolla, CA
  2. Bethesda, MD
  3. Cambridge, GB
  4. San Francisco, CA
+ Show Author Affiliations

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNAsyn-thetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Research Organization:
The Scripps Research Inst., La Jolla, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG03-00ER45812
Assignee:
The Scripps Research Institute (La Jolla, CA)
Patent Number(s):
7,993,872
Application Number:
10/561,121
OSTI ID:
1026521
Resource Relation:
Patent File Date: 2004 Apr 16
Country of Publication:
United States
Language:
English

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