Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate
Patent
·
OSTI ID:1016555
- Kennett Square, PA
- Lakewood, CO
- Centennial, CO
- Newark, DE
- Havertown, PA
- West Chester, PA
- New Hope, PA
Through screening of a Zymomonas mutant library the himA gene was found to be involved in the inhibitory effect of acetate on Zymomonas performance. Xylose-utilizing Zymomonas strains further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in mixed-sugars medium comprising xylose, and, in particular, in the presence of acetate.
- Research Organization:
- National Renewable Energy Laboratory (NREL), Golden, CO (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC36-08GO28308
- Assignee:
- E.I. du Pont de Nemours and Company (Wilmington, DE); Alliance for Sustainable Energy LLC (
- Patent Number(s):
- 7,897,396
- Application Number:
- US Patent Application 12/261,160
- OSTI ID:
- 1016555
- Country of Publication:
- United States
- Language:
- English
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