Investigation of exposure to Extremely Low Frequency (ELF) magnetic and electric fields: Ongoing animal studies
There is now convincing evidence from a large number of laboratories, that exposure to extremely low frequency (ELF) magnetic and electric fields produces biological responses in animals. Many of the observed effects appear to be directly or indirectly associated with the neural or neuroendocrine systems. Such effects include increased neuronal excitability, chemical and hormonal changes in the nervous system, altered behavioral responses, some of which are related to sensing the presence of the field, and changes in endogenous biological rhythms. Additional indices of general physiological status appear relatively unaffected by exposure, although effects have occasionally been described in bone growth and fracture repair, reproduction and development, and immune system function. A major current emphasis in laboratory research is to determine whether or not the reported epidemiological studies that suggest an association between EMF exposure and risk of cancer are supported in studies using animal models. Three major challenges exist for ongoing research: (1) knowledge about the mechanisms underlying observed bioeffects is incomplete, (2) researchers do not as yet understand what physical aspects of exposure produce biological responses, and (3) health consequences resulting from ELF exposure are unknown. Although no animal studies clearly demonstrate deleterious effects of ELF fields, several are suggestive of potential health impacts. From the perspective of laboratory animal studies, this paper will discuss biological responses to ELF magnetic and/or electric field exposures.
- Research Organization:
- Pacific Northwest Lab., Richland, WA (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States); Electric Power Research Inst., Palo Alto, CA (United States)
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 10148011
- Report Number(s):
- PNL-SA-23995; CONF-9403111-1; ON: DE94011239; TRN: 94:005448
- Resource Relation:
- Conference: Electric Power Research Institute (EPRI) EMF seminar on focus on research,Santa Clara, CA (United States),14-16 Mar 1994; Other Information: PBD: Mar 1994
- Country of Publication:
- United States
- Language:
- English
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