Host cells and methods for production of isobutanol

Anthony, Larry Cameron; He, Hongxian; Huang, Lixuan Lisa; Okeefe, Daniel P.; Kruckeberg, Arthur Leo; Li, Yougen; Maggio-Hall, Lori Ann; McElvain, Jessica; Nelson, Mark J.; Patnaik, Ranjan; Rothman, Steven Cary

Title: Host cells and methods for production of isobutanol

Patent · Tue Aug 23 00:00:00 EDT 2016

OSTI ID:1303694

Anthony, Larry Cameron; He, Hongxian; Huang, Lixuan Lisa; Okeefe, Daniel P.; Kruckeberg, Arthur Leo; Li, Yougen; Maggio-Hall, Lori Ann; McElvain, Jessica; Nelson, Mark J.; Patnaik, Ranjan; Rothman, Steven Cary

Provided herein are recombinant yeast host cells and methods for their use for production of isobutanol. Yeast host cells provided comprise an isobutanol biosynthetic pathway and at least one of reduced or eliminated aldehyde dehydrogenase activity, reduced or eliminated acetolactate reductase activity; or a heterologous polynucleotide encoding a polypeptide having ketol-acid reductoisomerase activity.

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Research Organization:: Butamax Advanced Biofuels LLC, Wilmington, DE (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AR0000006

Assignee:: Butamax Advanced Biofuels LLC (Wilmington, DE)

Patent Number(s):: 9,422,582

Application Number:: 13/840,676

OSTI ID:: 1303694

Resource Relation:: Patent File Date: 2013 Mar 15

Country of Publication:: United States

Language:: English

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