An embryo of protocells: The capsule of graphene with selective ion channels

Li, Zhan; Wang, Chunmei; Tian, Longlong; Bai, Jing; Yao, Huijun; Zhao, Yang; Zhang, Xin; Cao, Shiwei; Qi, Wei; Wang, Suomin; Shi, Keliang; Xu, Youwen; Mingliang, Zhang; Liu, Bo; Qiu, Hongdeng; Liu, Jie; Wu, Wangsuo; Wang, Xiaoli; Wenzhen, An

doi:10.1038/srep10258

Title: An embryo of protocells: The capsule of graphene with selective ion channels

Journal Article · Tue May 19 00:00:00 EDT 2015 · Scientific Reports

DOI:https://doi.org/10.1038/srep10258· OSTI ID:1258787

Li, Zhan ^[1]; Wang, Chunmei ^[2]; Tian, Longlong ^[3]; Bai, Jing ^[1]; Yao, Huijun ^[1]; Zhao, Yang ^[4]; Zhang, Xin ^[1]; Cao, Shiwei ^[1]; Qi, Wei ^[3]; Wang, Suomin ^[3]; Shi, Keliang ^[3]; Xu, Youwen ^[5]; Mingliang, Zhang ^[1]; Liu, Bo ^[3]; Qiu, Hongdeng ^[1]; Liu, Jie ^[1]; Wu, Wangsuo ^[3]; Wang, Xiaoli ^[2]; Wenzhen, An ^[3]

Chinese Academy of Sciences, Lanzhou (People's Republic of China)
Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou (People's Republic of China)
Lanzhou Univ., Lanzhou (People's Republic of China)
Fudan Univ., Shanghai (People's Republic of China); Lanzhou Univ., Lanzhou (People's Republic of China)
Brookhaven National Lab. (BNL), Upton, NY (United States)

In this study, the synthesis of artificial cell is a route for searching the origin of protocell. Here, we create a novel cell model of graphene capsules with selective ion channels, indicating that graphene might be an embryo of protocell membrane. Firstly, we found that the highly oxidized graphene and phospholipid-graphene oxide composite would curl into capsules under a strongly acidic saturated solution of heavy metallic salt solution at low temperature. Secondly, L-amino acids exhibited higher reactivity than D-amino acids on graphene oxides to form peptides, and the formed peptides in the influence of graphene would be transformed into a secondary structure, promoting the formation of left-handed proteins. Lastly, monolayer nanoporous graphene, prepared by unfocused ⁸⁴Kr²⁵⁺, has a high selectivity for permeation of the monovalent metal ions ( Rb⁺ > K⁺ > Cs⁺ > Na⁺ > Li⁺, based on permeation concentration), but does not allow Cl- go through. It is similar to K+ channels, which would cause an influx of K⁺ into capsule of graphene with the increase of pH in the primitive ocean, creating a suitable inner condition for the origin of life. Therefore, we built a model cell of graphene, which would provide a route for reproducing the origin of life.

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Research Organization:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Organization:: USDOE

OSTI ID:: 1258787

Journal Information:: Scientific Reports, Vol. 5; ISSN 2045-2322

Publisher:: Nature Publishing GroupCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 10 works

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Title: An embryo of protocells: The capsule of graphene with selective ion channels

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