Continuous Succinic Acid Production by Actinobacillus succinogenes on Xylose-Enriched Hydrolysate

Bradfield, Michael F. A.; Mohagheghi, Ali; Salvachua, Davinia; Smith, Holly; Black, Brenna A.; Dowe, Nancy; Beckham, Gregg T.; Nicol, Willie

doi:10.1186/s13068-015-0363-3

Title: Continuous Succinic Acid Production by Actinobacillus succinogenes on Xylose-Enriched Hydrolysate

Journal Article · Sat Nov 14 00:00:00 EST 2015 · Biotechnology for Biofuels

DOI:https://doi.org/10.1186/s13068-015-0363-3· OSTI ID:1233689

Bradfield, Michael F. A. ^[1]; Mohagheghi, Ali ^[2]; Salvachua, Davinia ^[2]; Smith, Holly ^[2]; Black, Brenna A. ^[2]; Dowe, Nancy ^[2]; Beckham, Gregg T. ^[2]; Nicol, Willie ^[3]

Univ. of Pretoria, Hatfield (South Africa); National Renewable Energy Lab. (NREL), Golden, CO (United States)
National Renewable Energy Lab. (NREL), Golden, CO (United States)
Univ. of Pretoria, Hatfield (South Africa)

Bio-manufacturing of high-value chemicals in parallel to renewable biofuels has the potential to dramatically improve the overall economic landscape of integrated lignocellulosic biorefineries. However, this will require the generation of carbohydrate streams from lignocellulose in a form suitable for efficient microbial conversion and downstream processing appropriate to the desired end use, making overall process development, along with selection of appropriate target molecules, crucial to the integrated biorefinery. Succinic acid (SA), a high-value target molecule, can be biologically produced from sugars and has the potential to serve as a platform chemical for various chemical and polymer applications. However, the feasibility of microbial SA production at industrially relevant productivities and yields from lignocellulosic biorefinery streams has not yet been reported.

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Research Organization:: National Renewable Energy Laboratory (NREL), Golden, CO (United States)

Sponsoring Organization:: USDOE Office of Energy Efficiency and Renewable Energy (EERE), Sustainable Transportation Office. Bioenergy Technologies Office

Grant/Contract Number:: AC36-08GO28308

OSTI ID:: 1233689

Report Number(s):: NREL/JA-5100-65596

Journal Information:: Biotechnology for Biofuels, Vol. 8; Related Information: Biotechnology for Biofuels; ISSN 1754-6834

Publisher:: BioMed CentralCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 71 works

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