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Title: Rapid prototyping of microchannels with surface patterns for fabrication of polymer fibers

Journal Article · · RSC Advances
DOI:https://doi.org/10.1039/c5ra15154f· OSTI ID:1227413
 [1];  [1];  [2]
  1. Iowa State Univ., Ames, IA (United States)
  2. Iowa State Univ. and Ames Lab., Ames, IA (United States); Ames National Lab., Iowa

Microfluidic technology has provided innovative solutions to numerous problems, but the cost of designing and fabricating microfluidic channels is impeding its expansion. In this study, Shrinky-Dink thermoplastic sheets are used to create multilayered complex templates for microfluidic channels. We also used inkjet and laserjet printers to raise a predetermined microchannel geometry by depositing several layers of ink for each feature consecutively. We achieved feature heights over 100 μm, which were measured and compared with surface profilometry. Templates closest to the target geometry were then used to create microfluidic devices from soft-lithography with the molds as a template. These microfluidic devices were, futhermore used to fabricate polymer microfibers using the microfluidic focusing approach to demonstrate the potential that this process has for microfluidic applications. Finally, an economic analysis was conducted to compare the price of common microfluidic template manufacturing methods. We showed that multilayer microchannels can be created significantly quicker and cheaper than current methods for design prototyping and point-of-care applications in the biomedical area.

Research Organization:
Ames Lab., Ames, IA (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Workforce Development for Teachers and Scientists (WDTS)
Grant/Contract Number:
AC02-07CH11358; Science Undergraduate Laboratory Internship (SULI)
OSTI ID:
1227413
Report Number(s):
IS-J-8796; RSCACL
Journal Information:
RSC Advances, Vol. 5, Issue 87; ISSN 2046-2069
Publisher:
Royal Society of ChemistryCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 15 works
Citation information provided by
Web of Science

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Cited By (5)

Multifunctional Micro/Nanoscale Fibers Based on Microfluidic Spinning Technology journal October 2019
3D Microfibrous Scaffolds Selectively Promotes Proliferation and Glial Differentiation of Adult Neural Stem Cells: A Platform to Tune Cellular Behavior in Neural Tissue Engineering journal November 2018
Mechanical and physical properties of poly(vinyl alcohol) microfibers fabricated by a microfluidic approach journal January 2016
Design and Analysis of Fused Deposition Modeling 3D Printer Nozzle for Color Mixing journal January 2017
3D Microfibrous Scaffolds Selectively Promotes Proliferation and Glial Differentiation of Adult Neural Stem Cells: A Platform to Tune Cellular Behavior in Neural Tissue Engineering journal November 2018

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