Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects
Abstract
Plant metabolomics has matured and modern plant metabolomics has accelerated gene discoveries and the elucidation of a variety of plant natural product biosynthetic pathways. This study highlights specific examples of the discovery and characterization of novel genes and enzymes associated with the biosynthesis of natural products such as flavonoids, glucosinolates, terpenoids, and alkaloids. Additional examples of the integration of metabolomics with genome-based functional characterizations of plant natural products that are important to modern pharmaceutical technology are also reviewed. This article also provides a substantial review of recent technical advances in mass spectrometry imaging, nuclear magnetic resonance imaging, integrated LC-MS-SPE-NMR for metabolite identifications, and x-ray crystallography of microgram quantities for structural determinations. The review closes with a discussion on the future prospects of metabolomics related to crop species and herbal medicine.
- Authors:
-
- The Samuel Roberts Noble Foundation, Ardmore, OK (United States)
- Iowa State Univ., Ames, IA (United States); Ames Lab., Ames, IA (United States)
- RIKEN Center for Sustainable Resource Science, Tsurumi-ku (Japan); Chiba Univ., Chuo-ku (Japan)
- Publication Date:
- Research Org.:
- Ames Laboratory (AMES), Ames, IA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1227150
- Report Number(s):
- IS-J-8609
Journal ID: ISSN 0265-0568; NPRRDF
- Grant/Contract Number:
- AC02-07CH11358
- Resource Type:
- Journal Article: Accepted Manuscript
- Journal Name:
- Natural Product Reports
- Additional Journal Information:
- Journal Volume: 32; Journal Issue: 2; Journal ID: ISSN 0265-0568
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES
Citation Formats
Sumner, Lloyd W., Lei, Zhentian, Nikolau, Basil J., and Saito, Kazuki. Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects. United States: N. p., 2014.
Web. doi:10.1039/c4np00072b.
Sumner, Lloyd W., Lei, Zhentian, Nikolau, Basil J., & Saito, Kazuki. Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects. United States. https://doi.org/10.1039/c4np00072b
Sumner, Lloyd W., Lei, Zhentian, Nikolau, Basil J., and Saito, Kazuki. 2014.
"Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects". United States. https://doi.org/10.1039/c4np00072b. https://www.osti.gov/servlets/purl/1227150.
@article{osti_1227150,
title = {Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects},
author = {Sumner, Lloyd W. and Lei, Zhentian and Nikolau, Basil J. and Saito, Kazuki},
abstractNote = {Plant metabolomics has matured and modern plant metabolomics has accelerated gene discoveries and the elucidation of a variety of plant natural product biosynthetic pathways. This study highlights specific examples of the discovery and characterization of novel genes and enzymes associated with the biosynthesis of natural products such as flavonoids, glucosinolates, terpenoids, and alkaloids. Additional examples of the integration of metabolomics with genome-based functional characterizations of plant natural products that are important to modern pharmaceutical technology are also reviewed. This article also provides a substantial review of recent technical advances in mass spectrometry imaging, nuclear magnetic resonance imaging, integrated LC-MS-SPE-NMR for metabolite identifications, and x-ray crystallography of microgram quantities for structural determinations. The review closes with a discussion on the future prospects of metabolomics related to crop species and herbal medicine.},
doi = {10.1039/c4np00072b},
url = {https://www.osti.gov/biblio/1227150},
journal = {Natural Product Reports},
issn = {0265-0568},
number = 2,
volume = 32,
place = {United States},
year = {Fri Oct 24 00:00:00 EDT 2014},
month = {Fri Oct 24 00:00:00 EDT 2014}
}
Web of Science
Works referenced in this record:
The Engines of Hippocrates: From the Dawn of Medicine to Medical and Pharmaceutical Informatics
book, October 2008
- Robson, Barry; Baek, O. K.
The discovery of aspirin: a reappraisal
journal, December 2000
- Sneader, W.
- BMJ, Vol. 321, Issue 7276
The quinine connection
journal, January 1992
- Greenwood, David
- Journal of Antimicrobial Chemotherapy, Vol. 30, Issue 4
Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
journal, May 1971
- Wani, Mansukhlal C.; Taylor, Harold Lawrence; Wall, Monroe E.
- Journal of the American Chemical Society, Vol. 93, Issue 9
Artemisinin: Discovery from the Chinese Herbal Garden
journal, September 2011
- Miller, Louis H.; Su, Xinzhuan
- Cell, Vol. 146, Issue 6
The Genetic Map of Artemisia annua L. Identifies Loci Affecting Yield of the Antimalarial Drug Artemisinin
journal, January 2010
- Graham, I. A.; Besser, K.; Blumer, S.
- Science, Vol. 327, Issue 5963
The Use of Combining Ability Analysis to Identify Elite Parents for Artemisia annua F1 Hybrid Production
journal, April 2013
- Townsend, Theresa; Segura, Vincent; Chigeza, Godfree
- PLoS ONE, Vol. 8, Issue 4
Microbially Derived Artemisinin: A Biotechnology Solution to the Global Problem of Access to Affordable Antimalarial Drugs
journal, December 2007
- Keasling, Jay D.; Diagana, Thierry T.; Hale, Victoria
- The American Journal of Tropical Medicine and Hygiene, Vol. 77, Issue 6_Suppl
( R,S )-Reticuline 7- O -methyltransferase and ( R,S )-norcoclaurine 6- O -methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy
journal, December 2003
- Ounaroon, Anan; Decker, Gabriele; Schmidt, Jürgen
- The Plant Journal, Vol. 36, Issue 6
Studies of the Δ12 desaturase of Carthamus tinctorius L
journal, June 1985
- Gennity, Joseph M.; Stumpf, Paul K.
- Archives of Biochemistry and Biophysics, Vol. 239, Issue 2
Ricinoleic acid biosynthesis and triacylglycerol assembly in microsomal preparations from developing castor-bean (Ricinus communis) endosperm
journal, December 1991
- Bafor, M.; Smith, M. A.; Jonsson, L.
- Biochemical Journal, Vol. 280, Issue 2
Identification of Non-Heme Diiron Proteins That Catalyze Triple Bond and Epoxy Group Formation
journal, May 1998
- Lee, M.
- Science, Vol. 280, Issue 5365
Biosynthesis of Vernoleate (cis-12-Epoxyoctadeca-cis-9-enoate) in Microsomal Preparations from Developing Endosperm of Euphorbia lagascae
journal, May 1993
- Bafor, M.; Smith, M. A.; Jonsson, L.
- Archives of Biochemistry and Biophysics, Vol. 303, Issue 1
Formation of Conjugated Δ 8 ,Δ 10 -Double Bonds by Δ 12 -Oleic-acid Desaturase-related Enzymes : BIOSYNTHETIC ORIGIN OF CALENDIC ACID
journal, November 2000
- Cahoon, Edgar B.; Ripp, Kevin G.; Hall, Sarah E.
- Journal of Biological Chemistry, Vol. 276, Issue 4
Molecular Analysis of a Bifunctional Fatty Acid Conjugase/Desaturase from Tung. Implications for the Evolution of Plant Fatty Acid Diversity
journal, November 2002
- Dyer, John M.; Chapital, Dorselyn C.; Kuan, Jui-Chang W.
- Plant Physiology, Vol. 130, Issue 4
A bifunctional Δ6-fatty acyl acetylenase/desaturase from the moss Ceratodon purpureus: A new member of the cytochrome b5 superfamily
journal, June 2000
- Sperling, Petra; Lee, Michael; Girke, Thomas
- European Journal of Biochemistry, Vol. 267, Issue 12
Integration of metabolome data with metabolic networks reveals reporter reactions
journal, January 2006
- Çakir, Tunahan; Patil, Kiran Raosaheb; Önsan, Zeynep Ilsen
- Molecular Systems Biology, Vol. 2, Issue 1
Regulation of yeast oscillatory dynamics
journal, February 2007
- Murray, D. B.; Beckmann, M.; Kitano, H.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 7
When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation
journal, January 2006
- Kresnowati, M. T. A. P.; van Winden, W. A.; Almering, M. J. H.
- Molecular Systems Biology, Vol. 2, Issue 1
Evidence for cytochrome b5 as an electron donor in ricinoleic acid biosynthesis in microsomal preparations from developing castor bean (Ricinus communis L.)
journal, October 1992
- Smith, M. A.; Jonsson, L.; Stymne, S.
- Biochemical Journal, Vol. 287, Issue 1
The use of metabolomics integrated with transcriptomic and proteomic studies for identifying key steps involved in the control of nitrogen metabolism in crops such as maize
journal, August 2012
- Amiour, Nardjis; Imbaud, Sandrine; Clément, Gilles
- Journal of Experimental Botany, Vol. 63, Issue 14
Characterization of Three O -Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy
journal, April 2012
- Dang, Thu-Thuy T.; Facchini, Peter J.
- Plant Physiology, Vol. 159, Issue 2
Transcriptional and metabolic data integration and modeling for identification of active pathways
journal, June 2012
- Jauhiainen, A.; Nerman, O.; Michailidis, G.
- Biostatistics, Vol. 13, Issue 4
Integrative Comparative Analyses of Transcript and Metabolite Profiles from Pepper and Tomato Ripening and Development Stages Uncovers Species-Specific Patterns of Network Regulatory Behavior
journal, June 2012
- Osorio, Sonia; Alba, Rob; Nikoloski, Zoran
- Plant Physiology, Vol. 159, Issue 4
Metabolic engineering of new fatty acids in plants
journal, April 2005
- Singh, Surinder P.; Zhou, Xue-Rong; Liu, Qing
- Current Opinion in Plant Biology, Vol. 8, Issue 2, p. 197-203
Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes
journal, August 2006
- Gibon, Yves; Usadel, Bjoern; Blaesing, Oliver E.
- Genome Biology, Vol. 7, Issue 8, p. R76
PlantMetabolomics.org: A Web Portal for Plant Metabolomics Experiments
journal, February 2010
- Bais, Preeti; Moon, Stephanie M.; He, Kun
- Plant Physiology, Vol. 152, Issue 4
Metabolomics as a Hypothesis-Generating Functional Genomics Tool for the Annotation of Arabidopsis thaliana Genes of “Unknown Function”
journal, January 2012
- Quanbeck, Stephanie M.; Brachova, Libuse; Campbell, Alexis A.
- Frontiers in Plant Science, Vol. 3
Directed tagging of the Arabidopsis FATTY ACID ELONGATION1 (FAE1) gene with the maize transposon activator.
journal, March 1995
- James, D. W.; Lim, E.; Keller, J.
- The Plant Cell, Vol. 7, Issue 3
ELO2 and ELO3 , Homologues of the Saccharomyces cerevisiae ELO1 Gene, Function in Fatty Acid Elongation and Are Required for Sphingolipid Formation
journal, July 1997
- Oh, Chan-Seok; Toke, David A.; Mandala, Suzanne
- Journal of Biological Chemistry, Vol. 272, Issue 28
Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis
journal, May 2012
- Ngaki, Micheline N.; Louie, Gordon V.; Philippe, Ryan N.
- Nature, Vol. 485, Issue 7399
The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access
journal, August 2008
- Goda, Hideki; Sasaki, Eriko; Akiyama, Kenji
- The Plant Journal, Vol. 55, Issue 3
Medicinal Plants: A Public Resource for Metabolomics and Hypothesis Development
journal, November 2012
- Wurtele, Eve; Chappell, Joe; Jones, A.
- Metabolites, Vol. 2, Issue 4
A proposed framework for the description of plant metabolomics experiments and their results
journal, December 2004
- Jenkins, Helen; Hardy, Nigel; Beckmann, Manfred
- Nature Biotechnology, Vol. 22, Issue 12
A global approach to analysis and interpretation of metabolic data for plant natural product discovery
journal, January 2013
- Hur, Manhoi; Campbell, Alexis Ann; Almeida-de-Macedo, Marcia
- Natural Product Reports, Vol. 30, Issue 4
A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in Catharanthus roseus
journal, March 2011
- Giddings, Lesley-Ann; Liscombe, David K.; Hamilton, John P.
- Journal of Biological Chemistry, Vol. 286, Issue 19
Functional Identification of Valerena-1,10-diene Synthase, a Terpene Synthase Catalyzing a Unique Chemical Cascade in the Biosynthesis of Biologically Active Sesquiterpenes in Valeriana officinalis
journal, December 2012
- Yeo, Yun-Soo; Nybo, S. Eric; Chittiboyina, Amar G.
- Journal of Biological Chemistry, Vol. 288, Issue 5
Metabolic engineering of sesquiterpene metabolism in yeast
journal, May 2007
- Takahashi, Shunji; Yeo, Yunsoo; Greenhagen, Bryan T.
- Biotechnology and Bioengineering, Vol. 97, Issue 1
Identification and biosynthesis of acylphloroglucinols in Hypericum gentianoides
journal, May 2013
- Crispin, Matthew C.; Hur, Manhoi; Park, Taeseong
- Physiologia Plantarum, Vol. 148, Issue 3
Phytochemical genomics — a new trend
journal, June 2013
- Saito, Kazuki
- Current Opinion in Plant Biology, Vol. 16, Issue 3
The future of metabolic phytochemistry: Larger numbers of metabolites, higher resolution, greater understanding
journal, November 2007
- Fernie, Alisdair R.
- Phytochemistry, Vol. 68, Issue 22-24
Metabolomics for Functional Genomics, Systems Biology, and Biotechnology
journal, June 2010
- Saito, Kazuki; Matsuda, Fumio
- Annual Review of Plant Biology, Vol. 61, Issue 1
Functional genomics for plant natural product biosynthesis
journal, January 2009
- Yonekura-Sakakibara, Keiko; Saito, Kazuki
- Natural Product Reports, Vol. 26, Issue 11
The flavonoid biosynthetic pathway in Arabidopsis: Structural and genetic diversity
journal, November 2013
- Saito, Kazuki; Yonekura-Sakakibara, Keiko; Nakabayashi, Ryo
- Plant Physiology and Biochemistry, Vol. 72
Genetics and Biochemistry of seed Flavonoids
journal, June 2006
- Lepiniec, Loïc; Debeaujon, Isabelle; Routaboul, Jean-Marc
- Annual Review of Plant Biology, Vol. 57, Issue 1
UGT73C6 and UGT78D1, Glycosyltransferases Involved in Flavonol Glycoside Biosynthesis in Arabidopsis thaliana
journal, August 2003
- Jones, Patrik; Messner, Burkhard; Nakajima, Jun-Ichiro
- Journal of Biological Chemistry, Vol. 278, Issue 45
Phytochemical genomics in Arabidopsis thaliana: A case study for functional identification of flavonoid biosynthesis genes
journal, January 2007
- Tohge, Takayuki; Yonekura-Sakakibara, Keiko; Niida, Rie
- Pure and Applied Chemistry, Vol. 79, Issue 4
Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor: Metabolomics and transcriptomics
journal, March 2005
- Tohge, Takayuki; Nishiyama, Yasutaka; Hirai, Masami Yokota
- The Plant Journal, Vol. 42, Issue 2
Two glycosyltransferases involved in anthocyanin modification delineated by transcriptome independent component analysis in Arabidopsis thaliana: Anthocyanin modification in Arabidopsis
journal, October 2011
- Yonekura-Sakakibara, Keiko; Fukushima, Atsushi; Nakabayashi, Ryo
- The Plant Journal, Vol. 69, Issue 1
Comprehensive Flavonol Profiling and Transcriptome Coexpression Analysis Leading to Decoding Gene–Metabolite Correlations in Arabidopsis
journal, August 2008
- Yonekura-Sakakibara, Keiko; Tohge, Takayuki; Matsuda, Fumio
- The Plant Cell, Vol. 20, Issue 8
Identification of a Flavonol 7- O -Rhamnosyltransferase Gene Determining Flavonoid Pattern in Arabidopsis by Transcriptome Coexpression Analysis and Reverse Genetics
journal, February 2007
- Yonekura-Sakakibara, Keiko; Tohge, Takayuki; Niida, Rie
- Journal of Biological Chemistry, Vol. 282, Issue 20
A flavonoid 3- O -glucoside:2″- O -glucosyltransferase responsible for terminal modification of pollen-specific flavonols in Arabidopsis thaliana
journal, July 2014
- Yonekura-Sakakibara, Keiko; Nakabayashi, Ryo; Sugawara, Satoko
- The Plant Journal, Vol. 79, Issue 5
Convergent evolution in the BAHD family of acyl transferases: identification and characterization of anthocyanin acyl transferases from Arabidopsis thaliana: Anthocyanin acyl transferases of Arabidopsis
journal, April 2007
- Luo, Jie; Nishiyama, Yasutaka; Fuell, Christine
- The Plant Journal, Vol. 50, Issue 4
Identification and characterization of the BAHD acyltransferase malonyl CoA: Anthocyanidin 5- O -glucoside-6″- O -malonyltransferase (At5MAT) in Arabidopsis thaliana
journal, February 2007
- D’Auria, John C.; Reichelt, Michael; Luck, Katrin
- FEBS Letters, Vol. 581, Issue 5
Functional Expression of an Arabidopsis cDNA Clone Encoding a Flavonol 3′-O-Methyltransferase and Characterization of the Gene Product
journal, March 2000
- Muzac, Ingrid; Wang, Jing; Anzellotti, Dominique
- Archives of Biochemistry and Biophysics, Vol. 375, Issue 2
AtMetExpress Development: A Phytochemical Atlas of Arabidopsis Development
journal, December 2009
- Matsuda, Fumio; Hirai, Masami Y.; Sasaki, Eriko
- Plant Physiology, Vol. 152, Issue 2
Mass Spectra-Based Framework for Automated Structural Elucidation of Metabolome Data to Explore Phytochemical Diversity
journal, January 2011
- Matsuda, Fumio; Nakabayashi, Ryo; Sawada, Yuji
- Frontiers in Plant Science, Vol. 2
Metabolomic Characterization of Knockout Mutants in Arabidopsis: Development of a Metabolite Profiling Database for Knockout Mutants in Arabidopsis
journal, May 2014
- Fukushima, Atsushi; Kusano, Miyako; Mejia, Ramon Francisco
- Plant Physiology, Vol. 165, Issue 3
Dissection of genotype-phenotype associations in rice grains using metabolome quantitative trait loci analysis: Metabolome QTL analysis of rice grain
journal, February 2012
- Matsuda, Fumio; Okazaki, Yozo; Oikawa, Akira
- The Plant Journal, Vol. 70, Issue 4
Genetic analysis of the metabolome exemplified using a rice population
journal, November 2013
- Gong, L.; Chen, W.; Gao, Y.
- Proceedings of the National Academy of Sciences, Vol. 110, Issue 50
The C -Glycosylation of Flavonoids in Cereals
journal, May 2009
- Brazier-Hicks, Melissa; Evans, Kathryn M.; Gershater, Markus C.
- Journal of Biological Chemistry, Vol. 284, Issue 27
Proanthocyanidins - a final frontier in flavonoid research?: Tansley Review
journal, November 2004
- Dixon, Richard A.; Xie, De-Yu; Sharma, Shashi B.
- New Phytologist, Vol. 165, Issue 1
Role of Anthocyanidin Reductase, Encoded by BANYULS in Plant Flavonoid Biosynthesis
journal, January 2003
- Xie, D. -Y.
- Science, Vol. 299, Issue 5605
Medicago glucosyltransferase UGT72L1: potential roles in proanthocyanidin biosynthesis
journal, April 2013
- Pang, Yongzhen; Cheng, Xiaofei; Huhman, David V.
- Planta, Vol. 238, Issue 1
Metabolic profiling and cytological analysis of proanthocyanidins in immature seeds of Arabidopsis thaliana flavonoid accumulation mutants: Proanthocyanidin accumulation pathway
journal, February 2010
- Kitamura, Satoshi; Matsuda, Fumio; Tohge, Takayuki
- The Plant Journal, Vol. 62, Issue 4
TRANSPARENT TESTA10 Encodes a Laccase-Like Enzyme Involved in Oxidative Polymerization of Flavonoids in Arabidopsis Seed Coat
journal, October 2005
- Pourcel, Lucille; Routaboul, Jean-Marc; Kerhoas, Lucien
- The Plant Cell, Vol. 17, Issue 11
The Mysteries of Proanthocyanidin Transport and Polymerization
journal, April 2010
- Zhao, Jian; Pang, Yongzhen; Dixon, Richard A.
- Plant Physiology, Vol. 153, Issue 2
From The Cover: Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana
journal, June 2004
- Hirai, M. Y.; Yano, M.; Goodenowe, D. B.
- Proceedings of the National Academy of Sciences, Vol. 101, Issue 27
Elucidation of Gene-to-Gene and Metabolite-to-Gene Networks in Arabidopsis by Integration of Metabolomics and Transcriptomics
journal, May 2005
- Hirai, Masami Yokota; Klein, Marion; Fujikawa, Yuuta
- Journal of Biological Chemistry, Vol. 280, Issue 27
Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis
journal, April 2007
- Hirai, M. Y.; Sugiyama, K.; Sawada, Y.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 15
ATTED-II: a database of co-expressed genes and cis elements for identifying co-regulated gene groups in Arabidopsis
journal, January 2007
- Obayashi, T.; Kinoshita, K.; Nakai, K.
- Nucleic Acids Research, Vol. 35, Issue Database
Combining Genome-Wide Association Mapping and Transcriptional Networks to Identify Novel Genes Controlling Glucosinolates in Arabidopsis thaliana
journal, August 2011
- Chan, Eva K. F.; Rowe, Heather C.; Corwin, Jason A.
- PLoS Biology, Vol. 9, Issue 8
Genetic Control of Natural Variation in Arabidopsis Glucosinolate Accumulation
journal, June 2001
- Kliebenstein, Daniel J.; Kroymann, Juergen; Brown, Paul
- Plant Physiology, Vol. 126, Issue 2
Identification of a flavin-monooxygenase as the S-oxygenating enzyme in aliphatic glucosinolate biosynthesis in Arabidopsis: Identification of a flavin monooxygenase
journal, April 2007
- Hansen, Bjarne G.; Kliebenstein, Daniel J.; Halkier, Barbara A.
- The Plant Journal, Vol. 50, Issue 5
Cytosolic γ-Glutamyl Peptidases Process Glutathione Conjugates in the Biosynthesis of Glucosinolates and Camalexin in Arabidopsis
journal, June 2011
- Geu-Flores, Fernando; Møldrup, Morten Emil; Böttcher, Christoph
- The Plant Cell, Vol. 23, Issue 6
Molecular activities, biosynthesis and evolution of triterpenoid saponins
journal, April 2011
- Augustin, Jörg M.; Kuzina, Vera; Andersen, Sven B.
- Phytochemistry, Vol. 72, Issue 6
Triterpenoid Biosynthesis and Engineering in Plants
journal, January 2011
- Sawai, Satoru; Saito, Kazuki
- Frontiers in Plant Science, Vol. 2
Natural product biosynthesis in Medicago species
journal, January 2014
- Gholami, Azra; De Geyter, Nathan; Pollier, Jacob
- Natural Product Reports, Vol. 31, Issue 3
Licorice -amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin
journal, September 2008
- Seki, H.; Ohyama, K.; Sawai, S.
- Proceedings of the National Academy of Sciences, Vol. 105, Issue 37
Triterpene Functional Genomics in Licorice for Identification of CYP72A154 Involved in the Biosynthesis of Glycyrrhizin
journal, November 2011
- Seki, Hikaru; Sawai, Satoru; Ohyama, Kiyoshi
- The Plant Cell, Vol. 23, Issue 11
Medicago truncatula CYP716A12 Is a Multifunctional Oxidase Involved in the Biosynthesis of Hemolytic Saponins
journal, August 2011
- Carelli, Maria; Biazzi, Elisa; Panara, Francesco
- The Plant Cell, Vol. 23, Issue 8
CYP716A Subfamily Members are Multifunctional Oxidases in Triterpenoid Biosynthesis
journal, October 2011
- Fukushima, Ery O.; Seki, Hikaru; Ohyama, Kiyoshi
- Plant and Cell Physiology, Vol. 52, Issue 12
Genomic and Coexpression Analyses Predict Multiple Genes Involved in Triterpene Saponin Biosynthesis in Medicago truncatula
journal, March 2010
- Naoumkina, Marina A.; Modolo, Luzia V.; Huhman, David V.
- The Plant Cell, Vol. 22, Issue 3
UDP-Glycosyltransferases from the UGT73C Subfamily in Barbarea vulgaris Catalyze Sapogenin 3- O -Glucosylation in Saponin-Mediated Insect Resistance
journal, October 2012
- Augustin, Jörg M.; Drok, Sylvia; Shinoda, Tetsuro
- Plant Physiology, Vol. 160, Issue 4
The Sg-1 Glycosyltransferase Locus Regulates Structural Diversity of Triterpenoid Saponins of Soybean
journal, May 2012
- Sayama, Takashi; Ono, Eiichiro; Takagi, Kyoko
- The Plant Cell, Vol. 24, Issue 5
Gene Clusters for Secondary Metabolic Pathways: An Emerging Theme in Plant Biology: Figure 1.
journal, October 2010
- Osbourn, Anne
- Plant Physiology, Vol. 154, Issue 2
The rise of operon-like gene clusters in plants
journal, July 2014
- Boycheva, Svetlana; Daviet, Laurent; Wolfender, Jean-Luc
- Trends in Plant Science, Vol. 19, Issue 7
A gene cluster for secondary metabolism in oat: Implications for the evolution of metabolic diversity in plants
journal, May 2004
- Qi, X.; Bakht, S.; Leggett, M.
- Proceedings of the National Academy of Sciences, Vol. 101, Issue 21
Metabolic Diversification--Independent Assembly of Operon-Like Gene Clusters in Different Plants
journal, April 2008
- Field, B.; Osbourn, A. E.
- Science, Vol. 320, Issue 5875
Formation of plant metabolic gene clusters within dynamic chromosomal regions
journal, August 2011
- Field, B.; Fiston-Lavier, A. -S.; Kemen, A.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 38
Biosynthesis of Antinutritional Alkaloids in Solanaceous Crops Is Mediated by Clustered Genes
journal, June 2013
- Itkin, M.; Heinig, U.; Tzfadia, O.
- Science, Vol. 341, Issue 6142
Sterol Side Chain Reductase 2 Is a Key Enzyme in the Biosynthesis of Cholesterol, the Common Precursor of Toxic Steroidal Glycoalkaloids in Potato
journal, September 2014
- Sawai, S.; Ohyama, K.; Yasumoto, S.
- The Plant Cell, Vol. 26, Issue 9
CYP719B1 Is Salutaridine Synthase, the C-C Phenol-coupling Enzyme of Morphine Biosynthesis in Opium Poppy
journal, June 2009
- Gesell, Andreas; Rolf, Megan; Ziegler, Jörg
- Journal of Biological Chemistry, Vol. 284, Issue 36
Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy
journal, March 2010
- Hagel, Jillian M.; Facchini, Peter J.
- Nature Chemical Biology, Vol. 6, Issue 4
A Papaver somniferum 10-Gene Cluster for Synthesis of the Anticancer Alkaloid Noscapine
journal, May 2012
- Winzer, Thilo; Gazda, Valeria; He, Zhesi
- Science, Vol. 336, Issue 6089
An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis
journal, November 2012
- Geu-Flores, Fernando; Sherden, Nathaniel H.; Courdavault, Vincent
- Nature, Vol. 492, Issue 7427
A 7-Deoxyloganetic Acid Glucosyltransferase Contributes a Key Step in Secologanin Biosynthesis in Madagascar Periwinkle
journal, October 2013
- Asada, Keisuke; Salim, Vonny; Masada-Atsumi, Sayaka
- The Plant Cell, Vol. 25, Issue 10
The seco-iridoid pathway from Catharanthus roseus
journal, April 2014
- Miettinen, Karel; Dong, Lemeng; Navrot, Nicolas
- Nature Communications, Vol. 5, Issue 1
7-Deoxyloganetic acid synthase catalyzes a key 3 step oxidation to form 7-deoxyloganetic acid in Catharanthus roseus iridoid biosynthesis
journal, May 2014
- Salim, Vonny; Wiens, Brent; Masada-Atsumi, Sayaka
- Phytochemistry, Vol. 101
Coupling Deep Transcriptome Analysis with Untargeted Metabolic Profiling in Ophiorrhiza pumila to Further the Understanding of the Biosynthesis of the Anti-Cancer Alkaloid Camptothecin and Anthraquinones
journal, April 2013
- Yamazaki, Mami; Mochida, Keiichi; Asano, Takashi
- Plant and Cell Physiology, Vol. 54, Issue 5
Suppression of camptothecin biosynthetic genes results in metabolic modification of secondary products in hairy roots of Ophiorrhiza pumila
journal, July 2013
- Asano, Takashi; Kobayashi, Kanae; Kashihara, Emi
- Phytochemistry, Vol. 91
Metabolomics for unknown plant metabolites
journal, March 2013
- Nakabayashi, Ryo; Saito, Kazuki
- Analytical and Bioanalytical Chemistry, Vol. 405, Issue 15
Quinolizidine alkaloid biosynthesis: recent advances and future prospects
journal, January 2012
- Bunsupa, Somnuk; Yamazaki, Mami; Saito, Kazuki
- Frontiers in Plant Science, Vol. 3
Lysine Decarboxylase Catalyzes the First Step of Quinolizidine Alkaloid Biosynthesis and Coevolved with Alkaloid Production in Leguminosae
journal, March 2012
- Bunsupa, Somnuk; Katayama, Kae; Ikeura, Emi
- The Plant Cell, Vol. 24, Issue 3
Microspectrophotometric measurement of pH and pH effect on color of petal epidermal cells
journal, April 1975
- Stewart, Robert N.; Norris, Karl H.; Asen, Sam
- Phytochemistry, Vol. 14, Issue 4
Chalcone Synthase Localization in Early Stages of Plant Development. I. Immunohistochemical Use of Plasmolysis for Localizing the Enzyme in Epidermal Cell Cytoplasm of Illuminated Buckwheat Hypocotyls
journal, January 1995
- Zobel, Alicja M.; Hrazdina, Geza
- Biotechnic & Histochemistry, Vol. 70, Issue 1
The TTG Gene Is Required to Specify Epidermal Cell Fate and Cell Patterning in the Arabidopsis Root
journal, December 1994
- Galway, Moira E.; Masucci, James D.; Lloyd, Alan M.
- Developmental Biology, Vol. 166, Issue 2
Flower colour intensity depends on specialized cell shape controlled by a Myb-related transcription factor
journal, June 1994
- Noda, Ken-ichi; Glover, Beverley J.; Linstead, Paul
- Nature, Vol. 369, Issue 6482
Single‐cell dissection and microdroplet chemistry
journal, April 2001
- Outlaw, William H.; Zhang, Shuqiu
- Journal of Experimental Botany, Vol. 52, Issue 356
Enzymic Determination of Metabolites in the Subcellular Compartments of Spinach Protoplasts
journal, July 1980
- Wirtz, Wolfgang; Stitt, Mark; Heldt, Hans W.
- Plant Physiology, Vol. 66, Issue 1
Metabolite levels during induction in the chloroplast and extrachloroplast compartments of spinach protoplasts
journal, November 1980
- Stitt, Mark; Wirtz, Wolfgang; Heldt, Hans W.
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 593, Issue 1
Analysis of the compartmentalized metabolome – a validation of the non-aqueous fractionation technique
journal, January 2011
- Klie, Sebastian
- Frontiers in Plant Science, Vol. 2
Single cell technology
journal, December 2003
- Kehr, Julia
- Current Opinion in Plant Biology, Vol. 6, Issue 6
Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry
journal, January 2003
- Reyzer, Michelle L.; Hsieh, Yunsheng; Ng, Kwokei
- Journal of Mass Spectrometry, Vol. 38, Issue 10
Tissue Profiling by Mass Spectrometry: A Review of Methodology and Applications
journal, January 2005
- Caldwell, Robert L.; Caprioli, Richard M.
- Molecular & Cellular Proteomics, Vol. 4, Issue 4
Use of mass spectrometry for imaging metabolites in plants: Mass spectrometry for imaging metabolites in plants
journal, March 2012
- Lee, Young Jin; Perdian, David C.; Song, Zhihong
- The Plant Journal, Vol. 70, Issue 1
Direct Profiling of Proteins in Biological Tissue Sections by MALDI Mass Spectrometry
journal, December 1999
- Chaurand, Pierre; Stoeckli, Markus; Caprioli, Richard M.
- Analytical Chemistry, Vol. 71, Issue 23
The NMR Microscope: a Unique and Promising Tool for Plant Science
journal, August 2000
- Ishida, N.
- Annals of Botany, Vol. 86, Issue 2
Functional imaging of plants by magnetic resonance experiments
journal, July 2001
- Köckenberger, Walter
- Trends in Plant Science, Vol. 6, Issue 7
Surveying the plant’s world by magnetic resonance imaging: Surveying the plant’s world by MRI
journal, March 2012
- Borisjuk, Ljudmilla; Rolletschek, Hardy; Neuberger, Thomas
- The Plant Journal, Vol. 70, Issue 1
MRI of plants and foods
journal, April 2013
- Van As, Henk; van Duynhoven, John
- Journal of Magnetic Resonance, Vol. 229
Label free biochemical 2D and 3D imaging using secondary ion mass spectrometry
journal, October 2011
- Fletcher, John S.; Vickerman, John C.; Winograd, Nicholas
- Current Opinion in Chemical Biology, Vol. 15, Issue 5
3D Imaging by Mass Spectrometry: A New Frontier
journal, February 2012
- Seeley, Erin H.; Caprioli, Richard M.
- Analytical Chemistry, Vol. 84, Issue 5
Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary ions
journal, December 2010
- Fletcher, John S.; Lockyer, Nicholas P.; Vickerman, John C.
- Mass Spectrometry Reviews, Vol. 30, Issue 1
Direct profiling and imaging of plant metabolites in intact tissues by using colloidal graphite-assisted laser desorption ionization mass spectrometry
journal, July 2008
- Cha, Sangwon; Zhang, Hui; Ilarslan, Hilal I.
- The Plant Journal, Vol. 55, Issue 2
Imaging Matrix Assisted Laser Desorption Ionization Mass Spectrometry: a technique to map plant metabolites within tissues at high spatial resolution
journal, September 2006
- Burrell, Mm; Earnshaw, Cj; Clench, Mr
- Journal of Experimental Botany, Vol. 58, Issue 4
Imaging with Mass Spectrometry
journal, October 1999
- Pacholski, M. L.; Winograd, N.
- Chemical Reviews, Vol. 99, Issue 10
The Early Entry of Al into Cells of Intact Soybean Roots (A Comparison of Three Developmental Root Regions Using Secondary Ion Mass Spectrometry Imaging)
journal, November 1996
- Lazof, D. B.; Goldsmith, J. G.; Rufty, T. W.
- Plant Physiology, Vol. 112, Issue 3
Imaging Nutrient Distributions in Plant Tissue Using Time-of-Flight Secondary Ion Mass Spectrometry and Scanning Electron Microscopy
journal, June 2008
- Metzner, Ralf; Schneider, Heike Ursula; Breuer, Uwe
- Plant Physiology, Vol. 147, Issue 4
High-Resolution Secondary Ion Mass Spectrometry Reveals the Contrasting Subcellular Distribution of Arsenic and Silicon in Rice Roots
journal, April 2011
- Moore, Katie L.; Schröder, Markus; Wu, Zhongchang
- Plant Physiology, Vol. 156, Issue 2
Localization of Flavonoids in Seeds by Cluster Time-of-Flight Secondary Ion Mass Spectrometry Imaging
journal, March 2010
- Seyer, Alexandre; Einhorn, Jacques; Brunelle, Alain
- Analytical Chemistry, Vol. 82, Issue 6
Elemental imaging at the nanoscale: NanoSIMS and complementary techniques for element localisation in plants
journal, November 2011
- Moore, Katie L.; Lombi, Enzo; Zhao, Fang-Jie
- Analytical and Bioanalytical Chemistry, Vol. 402, Issue 10
Matrix-free UV-laser desorption/ionization (LDI) mass spectrometric imaging at the single-cell level: distribution of secondary metabolites of Arabidopsis thaliana and Hypericum species: Matrix-free UV-LDI mass spectrometric imaging at the single-cell level
journal, December 2009
- Hölscher, Dirk; Shroff, Rohit; Knop, Katrin
- The Plant Journal, Vol. 60, Issue 5
Direct Profiling and Imaging of Epicuticular Waxes on Arabidopsis thaliana by Laser Desorption/Ionization Mass Spectrometry Using Silver Colloid as a Matrix
journal, April 2009
- Cha, Sangwon; Song, Zhihong; Nikolau, Basil J.
- Analytical Chemistry, Vol. 81, Issue 8
Ambient Molecular Imaging and Depth Profiling of Live Tissue by Infrared Laser Ablation Electrospray Ionization Mass Spectrometry
journal, June 2008
- Nemes, Peter; Barton, Alexis A.; Li, Yue
- Analytical Chemistry, Vol. 80, Issue 12
Three-Dimensional Imaging of Metabolites in Tissues under Ambient Conditions by Laser Ablation Electrospray Ionization Mass Spectrometry
journal, August 2009
- Nemes, Peter; Barton, Alexis A.; Vertes, Akos
- Analytical Chemistry, Vol. 81, Issue 16
Laser Ablation Electrospray Ionization for Atmospheric Pressure, in Vivo, and Imaging Mass Spectrometry
journal, November 2007
- Nemes, Peter; Vertes, Akos
- Analytical Chemistry, Vol. 79, Issue 21
Simultaneous Imaging of Small Metabolites and Lipids in Rat Brain Tissues at Atmospheric Pressure by Laser Ablation Electrospray Ionization Mass Spectrometry
journal, February 2010
- Nemes, Peter; Woods, Amina S.; Vertes, Akos
- Analytical Chemistry, Vol. 82, Issue 3
Direct analysis of lipids and small metabolites in mouse brain tissue by AP IR-MALDI and reactive LAESI mass spectrometry
journal, January 2010
- Shrestha, Bindesh; Nemes, Peter; Nazarian, Javad
- The Analyst, Vol. 135, Issue 4
Ablation and analysis of small cell populations and single cells by consecutive laser pulses
journal, June 2010
- Shrestha, Bindesh; Nemes, Peter; Vertes, Akos
- Applied Physics A, Vol. 101, Issue 1
In Situ Cell-by-Cell Imaging and Analysis of Small Cell Populations by Mass Spectrometry
journal, April 2011
- Shrestha, Bindesh; Patt, Joseph M.; Vertes, Akos
- Analytical Chemistry, Vol. 83, Issue 8
Mass spectrometric imaging of small molecules
journal, August 2010
- Svatoš, Aleš
- Trends in Biotechnology, Vol. 28, Issue 8
Spatially resolved analysis of small molecules by matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI)
journal, November 2011
- Peukert, Manuela; Matros, Andrea; Lattanzio, Giuseppe
- New Phytologist, Vol. 193, Issue 3
Direct Plant Tissue Analysis and Imprint Imaging by Desorption Electrospray Ionization Mass Spectrometry
journal, July 2011
- Müller, Thomas; Oradu, Sheran; Ifa, Demian R.
- Analytical Chemistry, Vol. 83, Issue 14
Imaging MS Methodology for More Chemical Information in Less Data Acquisition Time Utilizing a Hybrid Linear Ion Trap−Orbitrap Mass Spectrometer
journal, November 2010
- Perdian, D. C.; Lee, Young Jin
- Analytical Chemistry, Vol. 82, Issue 22
Determination of agrochemical compounds in soya plants by imaging matrix-assisted laser desorption/ionisation mass spectrometry
journal, January 2005
- Mullen, Alexander K.; Clench, Malcolm R.; Crosland, Susan
- Rapid Communications in Mass Spectrometry, Vol. 19, Issue 18
Localization of water-soluble carbohydrates in wheat stems using imaging matrix-assisted laser desorption ionization mass spectrometry
journal, November 2006
- Robinson, Sarah; Warburton, Karen; Seymour, Mark
- New Phytologist, Vol. 173, Issue 2
MALDI imaging of neutral cuticular lipids in insects and plants
journal, February 2010
- Vrkoslav, Vladimír; Muck, Alexander; Cvačka, Josef
- Journal of the American Society for Mass Spectrometry, Vol. 21, Issue 2
Combining intensity correlation analysis and MALDI imaging to study the distribution of flavonols and dihydrochalcones in Golden Delicious apples
journal, November 2011
- Franceschi, Pietro; Dong, Yonghui; Strupat, Kerstin
- Journal of Experimental Botany, Vol. 63, Issue 3
Direct analysis for the distribution of toxic glycoalkaloids in potato tuber tissue using matrix-assisted laser desorption/ionization mass spectrometric imaging
journal, August 2012
- Ha, Miyoung; Kwak, Jong Hwan; Kim, Yangsun
- Food Chemistry, Vol. 133, Issue 4
Mass spectrometry imaging of glucosinolates in Arabidopsis flowers and siliques
journal, May 2012
- Sarsby, Joscelyn; Towers, Mark W.; Stain, Chris
- Phytochemistry, Vol. 77
Visualization of anthocyanin species in rabbiteye blueberry Vaccinium ashei by matrix-assisted laser desorption/ionization imaging mass spectrometry
journal, March 2012
- Yoshimura, Yukihiro; Enomoto, Hirofumi; Moriyama, Tatsuya
- Analytical and Bioanalytical Chemistry, Vol. 403, Issue 7
Different Localization Patterns of Anthocyanin Species in the Pericarp of Black Rice Revealed by Imaging Mass Spectrometry
journal, February 2012
- Yoshimura, Yukihiro; Zaima, Nobuhiro; Moriyama, Tatsuya
- PLoS ONE, Vol. 7, Issue 2
MALDI mass spectrometry-assisted molecular imaging of metabolites during nitrogen fixation in the Medicago truncatula - Sinorhizobium meliloti symbiosis
journal, May 2013
- Ye, Hui; Gemperline, Erin; Venkateshwaran, Muthusubramanian
- The Plant Journal, Vol. 75, Issue 1
High-Spatial and High-Mass Resolution Imaging of Surface Metabolites of Arabidopsis thaliana by Laser Desorption-Ionization Mass Spectrometry Using Colloidal Silver
journal, April 2010
- Jun, Ji Hyun; Song, Zhihong; Liu, Zhenjiu
- Analytical Chemistry, Vol. 82, Issue 8
In-situ probing of the biotic-abiotic boundary of plants by laser desorption/ionization time-of-flight mass spectrometry
journal, January 2005
- Sluszny, Chanan; Yeung, Edward S.; Nikolau, Basil J.
- Journal of the American Society for Mass Spectrometry, Vol. 16, Issue 1
Simulated splashes: Elucidating the mechanism of desorption electrospray ionization mass spectrometry
journal, October 2008
- Costa, Anthony B.; Graham Cooks, R.
- Chemical Physics Letters, Vol. 464, Issue 1-3
Non-Proximate Detection of Small and Large Molecules by Desorption Electrospray Ionization and Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry: Instrumentation and Applications in Forensics, Chemistry, and Biology
journal, September 2007
- Cotte-Rodríguez, Ismael; Mulligan, Christopher C.; Cooks, R. Graham
- Analytical Chemistry, Vol. 79, Issue 18
Desorption electrospray ionization using an Orbitrap mass spectrometer: exact mass measurements on drugs and peptides
journal, January 2006
- Hu, Qizhi; Talaty, Nari; Noll, Robert J.
- Rapid Communications in Mass Spectrometry, Vol. 20, Issue 22
New ionization methods and miniature mass spectrometers for biomedicine: DESI imaging for cancer diagnostics and paper spray ionization for therapeutic drug monitoring
journal, January 2011
- Cooks, R. Graham; Manicke, Nicholas E.; Dill, Allison L.
- Faraday Discussions, Vol. 149, p. 247-267
Lipid Profiles of Canine Invasive Transitional Cell Carcinoma of the Urinary Bladder and Adjacent Normal Tissue by Desorption Electrospray Ionization Imaging Mass Spectrometry
journal, November 2009
- Dill, Allison L.; Ifa, Demian R.; Manicke, Nicholas E.
- Analytical Chemistry, Vol. 81, Issue 21
Cholesterol Sulfate Imaging in Human Prostate Cancer Tissue by Desorption Electrospray Ionization Mass Spectrometry
journal, May 2010
- Eberlin, Livia S.; Dill, Allison L.; Costa, Anthony B.
- Analytical Chemistry, Vol. 82, Issue 9
Imaging of Human Lens Lipids by Desorption Electrospray Ionization Mass Spectrometry
journal, December 2010
- Ellis, Shane R.; Wu, Chunping; Deeley, Jane M.
- Journal of the American Society for Mass Spectrometry, Vol. 21, Issue 12
Mapping Lipid Alterations in Traumatically Injured Rat Spinal Cord by Desorption Electrospray Ionization Imaging Mass Spectrometry
journal, January 2011
- Girod, Marion; Shi, Yunzhou; Cheng, Ji-Xin
- Analytical Chemistry, Vol. 83, Issue 1
Development of capabilities for imaging mass spectrometry under ambient conditions with desorption electrospray ionization (DESI)
journal, January 2007
- Ifa, Demian R.; Wiseman, Justin M.; Song, Qingyu
- International Journal of Mass Spectrometry, Vol. 259, Issue 1-3
Imaging of Lipids in Atheroma by Desorption Electrospray Ionization Mass Spectrometry
journal, November 2009
- Manicke, Nicholas E.; Nefliu, Marcela; Wu, Chunping
- Analytical Chemistry, Vol. 81, Issue 21
Desorption electrospray ionization mass spectrometry: Imaging drugs and metabolites in tissues
journal, August 2008
- Wiseman, J. M.; Ifa, D. R.; Zhu, Y.
- Proceedings of the National Academy of Sciences, Vol. 105, Issue 47
Direct analysis of Stevia leaves for diterpene glycosides by desorption electrospray ionization mass spectrometry
journal, January 2009
- Jackson, Ayanna U.; Tata, Alessandra; Wu, Chunping
- The Analyst, Vol. 134, Issue 5
Rapid in situ detection of alkaloids in plant tissue under ambient conditions using desorption electrospray ionization
journal, January 2005
- Talaty, Nari; Takáts, Zoltán; Cooks, R. Graham
- The Analyst, Vol. 130, Issue 12
Nanospray desorption electrospray ionization: an ambient method for liquid-extraction surface sampling in mass spectrometry
journal, January 2010
- Roach, Patrick J.; Laskin, Julia; Laskin, Alexander
- The Analyst, Vol. 135, Issue 9
Mass spectrometric imaging as a high-spatial resolution tool for functional genomics: Tissue-specific gene expression of TT7 inferred from heterogeneous distribution of metabolites in Arabidopsis flowers
journal, January 2012
- Korte, Andrew R.; Song, Zhihong; Nikolau, Basil J.
- Anal. Methods, Vol. 4, Issue 2
A high-resolution scanning microprobe matrix-assisted laser desorption/ionization ion source for imaging analysis on an ion trap/Fourier transform ion cyclotron resonance mass spectrometer
journal, October 2008
- Koestler, Martin; Kirsch, Dieter; Hester, Alfons
- Rapid Communications in Mass Spectrometry, Vol. 22, Issue 20
Histology by Mass Spectrometry: Label-Free Tissue Characterization Obtained from High-Accuracy Bioanalytical Imaging
journal, April 2010
- Römpp, Andreas; Guenther, Sabine; Schober, Yvonne
- Angewandte Chemie International Edition, Vol. 49, Issue 22
Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance
journal, March 1973
- Lauterbur, P. C.
- Nature, Vol. 242, Issue 5394
Dynamic studies of phloem and xylein flow in fully differentiated plants by fast nuclear-magnetic-resonance microimaging
journal, March 1999
- Rokitta, M.; Peuke, A. D.; Zimmermann, U.
- Protoplasma, Vol. 209, Issue 1-2
Quantification of water transport in plants with NMR imaging
journal, October 2000
- Scheenen, T. W. J.; van Dusschoten, D.; de Jager, P. A.
- Journal of Experimental Botany, Vol. 51, Issue 351
Intact Plant Magnetic Resonance Imaging to Study Dynamics in Long-Distance Sap Flow and Flow-Conducting Surface Area
journal, April 2007
- Scheenen, T. W. J.; Vergeldt, F. J.; Heemskerk, A. M.
- Plant Physiology, Vol. 144, Issue 2
Intact plant MRI for the study of cell water relations, membrane permeability, cell-to-cell and long distance water transport
journal, November 2006
- Van As, H.
- Journal of Experimental Botany, Vol. 58, Issue 4
Most Water in the Tomato Truss Is Imported through the Xylem, Not the Phloem: A Nuclear Magnetic Resonance Flow Imaging Study
journal, August 2009
- Windt, Carel W.; Gerkema, Edo; Van As, Henk
- Plant Physiology, Vol. 151, Issue 2
3D MR microscopy with resolution by by
journal, September 2002
- Ciobanu, L.; Seeber, D. A.; Pennington, C. H.
- Journal of Magnetic Resonance, Vol. 158, Issue 1-2
Dynamic 13C/1H NMR imaging uncovers sugar allocation in the living seed: Sucrose allocation in seed
journal, April 2011
- Melkus, Gerd; Rolletschek, Hardy; Fuchs, Johannes
- Plant Biotechnology Journal, Vol. 9, Issue 9
The Metabolic Role of the Legume Endosperm: A Noninvasive Imaging Study
journal, September 2009
- Melkus, Gerd; Rolletschek, Hardy; Radchuk, Ruslana
- Plant Physiology, Vol. 151, Issue 3
Two- and three-dimensional mapping of the iron distribution in the apoplastic fluid of plant leaf tissue by means of magnetic resonance imaging
journal, October 2005
- Lambert, Jörg; Lampen, Peter; von Bohlen, Alex
- Analytical and Bioanalytical Chemistry, Vol. 384, Issue 1
Xenobiotic Monitoring in Plants by 19 F and 1 H Nuclear Magnetic Resonance Imaging and Spectroscopy : Uptake of Trifluoroacetic Acid in
journal, December 1989
- Rollins, Andrew; Barber, Jill; Elliott, Raymond
- Plant Physiology, Vol. 91, Issue 4
Nuclear magnetic resonance imaging of lipid in living plants
journal, October 2013
- Borisjuk, Ljudmilla; Rolletschek, Hardy; Neuberger, Thomas
- Progress in Lipid Research, Vol. 52, Issue 4
A Noninvasive Platform for Imaging and Quantifying Oil Storage in Submillimeter Tobacco Seed
journal, December 2012
- Fuchs, Johannes; Neuberger, Thomas; Rolletschek, Hardy
- Plant Physiology, Vol. 161, Issue 2
Potential of metabolomics as a functional genomics tool
journal, September 2004
- Bino, Raoul J.; Hall, Robert D.; Fiehn, Oliver
- Trends in Plant Science, Vol. 9, Issue 9
The role of reporting standards for metabolite annotation and identification in metabolomic studies
journal, October 2013
- Salek, Reza M.; Steinbeck, Christoph; Viant, Mark R.
- GigaScience, Vol. 2, Issue 1
Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics
journal, May 2012
- Dunn, Warwick B.; Erban, Alexander; Weber, Ralf J. M.
- Metabolomics, Vol. 9, Issue S1
Proposed minimum reporting standards for chemical analysis: Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)
journal, September 2007
- Sumner, Lloyd W.; Amberg, Alexander; Barrett, Dave
- Metabolomics, Vol. 3, Issue 3
Phytochemistry in the microgram domain—a LC-NMR perspective
journal, January 2005
- Wolfender, Jean-Luc; Queiroz, Emerson F.; Hostettmann, Kurt
- Magnetic Resonance in Chemistry, Vol. 43, Issue 9
Identification of Natural Products Using HPLC-SPE Combined with CapNMR
journal, January 2007
- Lambert, Maja; Wolfender, Jean-Luc; Stærk, Dan
- Analytical Chemistry, Vol. 79, Issue 2
LC-MS-SPE-NMR for the Isolation and Characterization of neo -Clerodane Diterpenoids from Teucrium luteum subsp. flavovirens ⊥
journal, May 2010
- Castro, Amaya; Moco, Sofia; Coll, Josep
- Journal of Natural Products, Vol. 73, Issue 5
A strategy for fast structural elucidation of metabolites in small volume plant extracts using automated MS-guided LC-MS-SPE-NMR: Metabolite identification using automated MS-guided SPE-NMR
journal, December 2011
- Hooft, Justin J. J.; Mihaleva, Velitchka; Vos, Ric C. H.
- Magnetic Resonance in Chemistry, Vol. 49
MassBank: a public repository for sharing mass spectral data for life sciences
journal, July 2010
- Horai, Hisayuki; Arita, Masanori; Kanaya, Shigehiko
- Journal of Mass Spectrometry, Vol. 45, Issue 7
HMDB 3.0—The Human Metabolome Database in 2013
journal, November 2012
- Wishart, David S.; Jewison, Timothy; Guo, An Chi
- Nucleic Acids Research, Vol. 41, Issue D1
METLIN: A Metabolite Mass Spectral Database
journal, January 2005
- Smith, Colin A.; Maille, Grace O??; Want, Elizabeth J.
- Therapeutic Drug Monitoring, Vol. 27, Issue 6
An accelerated workflow for untargeted metabolomics using the METLIN database
journal, September 2012
- Tautenhahn, Ralf; Cho, Kevin; Uritboonthai, Winnie
- Nature Biotechnology, Vol. 30, Issue 9
GMD@CSB.DB: the Golm Metabolome Database
journal, December 2004
- Kopka, J.; Schauer, N.; Krueger, S.
- Bioinformatics, Vol. 21, Issue 8
RIKEN tandem mass spectral database (ReSpect) for phytochemicals: A plant-specific MS/MS-based data resource and database
journal, October 2012
- Sawada, Yuji; Nakabayashi, Ryo; Yamada, Yutaka
- Phytochemistry, Vol. 82
MS/MS spectral tag-based annotation of non-targeted profile of plant secondary metabolites
journal, February 2009
- Matsuda, Fumio; Yonekura-Sakakibara, Keiko; Niida, Rie
- The Plant Journal, Vol. 57, Issue 3
MeltDB: a software platform for the analysis and integration of metabolomics experiment data
journal, September 2008
- Neuweger, Heiko; Albaum, Stefan P.; Dondrup, Michael
- Bioinformatics, Vol. 24, Issue 23
Metabolite identification via the Madison Metabolomics Consortium Database
journal, February 2008
- Cui, Qiu; Lewis, Ian A.; Hegeman, Adrian D.
- Nature Biotechnology, Vol. 26, Issue 2
Evaluation of the comparability of spectra generated using a tuning point protocol on twelve electrospray ionisation tandem-in-space mass spectrometers: Comparability of spectra generated using a tuning point protocol
journal, March 2011
- Champarnaud, E.; Hopley, C.
- Rapid Communications in Mass Spectrometry, Vol. 25, Issue 8
Computational mass spectrometry for small molecules
journal, March 2013
- Scheubert, Kerstin; Hufsky, Franziska; Böcker, Sebastian
- Journal of Cheminformatics, Vol. 5, Issue 1
MetFusion: integration of compound identification strategies: MetFusion
journal, February 2013
- Gerlich, Michael; Neumann, Steffen
- Journal of Mass Spectrometry, Vol. 48, Issue 3
In silico fragmentation for computer assisted identification of metabolite mass spectra
journal, March 2010
- Wolf, Sebastian; Schmidt, Stephan; Müller-Hannemann, Matthias
- BMC Bioinformatics, Vol. 11, Issue 1
FiD: a software for ab initio structural identification of product ions from tandem mass spectrometric data
journal, October 2008
- Heinonen, Markus; Rantanen, Ari; Mielikäinen, Taneli
- Rapid Communications in Mass Spectrometry, Vol. 22, Issue 19
LipidBlast in silico tandem mass spectrometry database for lipid identification
journal, June 2013
- Kind, Tobias; Liu, Kwang-Hyeon; Lee, Do Yup
- Nature Methods, Vol. 10, Issue 8
Identifying the Unknowns by Aligning Fragmentation Trees
journal, March 2012
- Rasche, Florian; Scheubert, Kerstin; Hufsky, Franziska
- Analytical Chemistry, Vol. 84, Issue 7
Chemical substructure identification by mass spectral library searching
journal, August 1995
- Stein, Stephen E.
- Journal of the American Society for Mass Spectrometry, Vol. 6, Issue 8
Prediction of MS/MS Data. 1. A Focus on Pharmaceuticals Containing Carboxylic Acids
journal, March 2004
- Bandu, Mary L.; Watkins, Kathryn R.; Bretthauer, Melinda L.
- Analytical Chemistry, Vol. 76, Issue 6
Approaches towards the automated interpretation and prediction of electrospray tandem mass spectra of non-peptidic combinatorial compounds
journal, January 2003
- Klagkou, Katerina; Pullen, Frank; Harrison, Mark
- Rapid Communications in Mass Spectrometry, Vol. 17, Issue 11
Sequence database searches viade novo peptide sequencing by tandem mass spectrometry
journal, June 1997
- Taylor, J. Alex; Johnson, Richard S.
- Rapid Communications in Mass Spectrometry, Vol. 11, Issue 9
In silico identification software (ISIS): a machine learning approach to tandem mass spectral identification of lipids
journal, May 2012
- Kangas, Lars J.; Metz, Thomas O.; Isaac, Giorgis
- Bioinformatics, Vol. 28, Issue 13
Congruent Strategies for Carbohydrate Sequencing. 2. FragLib: An MS n Spectral Library
journal, October 2005
- Zhang, Hailong; Singh, Suddham; Reinhold, Vernon N.
- Analytical Chemistry, Vol. 77, Issue 19
Strategy for Simulation of CID Spectra of N-Linked Oligosaccharides toward Glycomics
journal, April 2006
- Kameyama, Akihiko; Nakaya, Shuuichi; Ito, Hiromi
- Journal of Proteome Research, Vol. 5, Issue 4
High-Throughput and Multiplexed LC/MS/MRM Method for Targeted Metabolomics
journal, July 2010
- Wei, Ru; Li, Guodong; Seymour, Albert B.
- Analytical Chemistry, Vol. 82, Issue 13
Widely Targeted Metabolomics Based on Large-Scale MS/MS Data for Elucidating Metabolite Accumulation Patterns in Plants
journal, December 2008
- Sawada, Yuji; Akiyama, Kenji; Sakata, Akane
- Plant and Cell Physiology, Vol. 50, Issue 1
A Versatile Targeted Metabolomics Method for the Rapid Quantification of Multiple Classes of Phenolics in Fruits and Beverages
journal, March 2012
- Vrhovsek, Urska; Masuero, Domenico; Gasperotti, Mattia
- Journal of Agricultural and Food Chemistry, Vol. 60, Issue 36
A targeted metabolomics approach to understand differences in flavonoid biosynthesis in red and yellow raspberries
journal, November 2013
- Carvalho, Elisabete; Franceschi, Pietro; Feller, Antje
- Plant Physiology and Biochemistry, Vol. 72
False-positive liquid chromatography/tandem mass spectrometric confirmation of sebuthylazine residues using the identification points system according to EU directive 2002/657/EC due to a biogenic insecticide in tarragon
journal, April 2009
- Schürmann, Andreas; Dvorak, Veronika; Crüzer, Claudio
- Rapid Communications in Mass Spectrometry, Vol. 23, Issue 8
Proficiency study for the determination of nitrofuran metabolites in shrimps
journal, June 2006
- Hurtaud-Pessel, D.; Verdon, E.; Blot, J.
- Food Additives and Contaminants, Vol. 23, Issue 6
The (Un)Certainty of Selectivity in Liquid Chromatography Tandem Mass Spectrometry
journal, December 2012
- Berendsen, Bjorn J. A.; Stolker, Linda A. M.; Nielen, Michel W. F.
- Journal of The American Society for Mass Spectrometry, Vol. 24, Issue 1
Confirmation of organic micropollutants detected in environmental samples by liquid chromatography tandem mass spectrometry: Achievements and pitfalls
journal, November 2006
- Pozo, Óscar J.; Sancho, Juan V.; Ibáñez, María
- TrAC Trends in Analytical Chemistry, Vol. 25, Issue 10
Method for rapid metabolite profiling of drug candidates in fresh hepatocytes using liquid chromatography coupled with a hybrid quadrupole linear ion trap
journal, January 2007
- Gao, Hongying; Materne, Olivier L.; Howe, David L.
- Rapid Communications in Mass Spectrometry, Vol. 21, Issue 22
The Crystal Structure of Hexamethylene-Tetramine
journal, January 1923
- Dickinson, Roscoe G.; Raymond, Albert L.
- Journal of the American Chemical Society, Vol. 45, Issue 1
Dorothy crowfoot hodgkin (1910-1994)
journal, December 1994
- Glusker, Jenny P.
- Protein Science, Vol. 3, Issue 12
X-ray analysis on the nanogram to microgram scale using porous complexes
journal, March 2013
- Inokuma, Yasuhide; Yoshioka, Shota; Ariyoshi, Junko
- Nature, Vol. 495, Issue 7442
Preparation and guest-uptake protocol for a porous complex useful for 'crystal-free' crystallography
journal, January 2014
- Inokuma, Yasuhide; Yoshioka, Shota; Ariyoshi, Junko
- Nature Protocols, Vol. 9, Issue 2
Genetic analysis of metabolome–phenotype interactions: from model to crop species
journal, January 2013
- Carreno-Quintero, Natalia; Bouwmeester, Harro J.; Keurentjes, Joost J. B.
- Trends in Genetics, Vol. 29, Issue 1
Exploring molecular backgrounds of quality traits in rice by predictive models based on high-coverage metabolomics
journal, January 2011
- Redestig, Henning; Kusano, Miyako; Ebana, Kaworu
- BMC Systems Biology, Vol. 5, Issue 1
A genomics and multi-platform metabolomics approach to identify new traits of rice quality in traditional and improved varieties
journal, October 2011
- Calingacion, M. N.; Boualaphanh, C.; Daygon, V. D.
- Metabolomics, Vol. 8, Issue 5
Metabolome-genome-wide association study dissects genetic architecture for generating natural variation in rice secondary metabolism
journal, November 2014
- Matsuda, Fumio; Nakabayashi, Ryo; Yang, Zhigang
- The Plant Journal, Vol. 81, Issue 1
Drought Responses of Leaf Tissues from Wheat Cultivars of Differing Drought Tolerance at the Metabolite Level
journal, March 2012
- Bowne, Jairus B.; Erwin, Tim A.; Juttner, Juan
- Molecular Plant, Vol. 5, Issue 2
Whole-Genome Mapping of Agronomic and Metabolic Traits to Identify Novel Quantitative Trait Loci in Bread Wheat Grown in a Water-Limited Environment
journal, May 2013
- Hill, C. B.; Taylor, J. D.; Edwards, J.
- PLANT PHYSIOLOGY, Vol. 162, Issue 3
Transcriptomic, proteomic and metabolomic analysis of UV-B signaling in maize
journal, June 2011
- Casati, Paula; Campi, Mabel; Morrow, Darren J.
- BMC Genomics, Vol. 12, Issue 1
Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology
journal, January 2005
- Wang, Mei; Lamers, Robert-Jan A. N.; Korthout, Henrie A. A. J.
- Phytotherapy Research, Vol. 19, Issue 3
Metabolomics: Towards Understanding Traditional Chinese Medicine
journal, November 2010
- Zhang, Aihua; Sun, Hui; Wang, Zhigang
- Planta Medica, Vol. 76, Issue 17
Chemical substructure identification by mass spectral library searching
journal, August 1995
- Stein, S.
- Journal of the American Society for Mass Spectrometry, Vol. 6, Issue 8
Ambient mass spectrometry
journal, January 2017
- Fernández, Facundo M.; Garcia-Reyes, Juan F.
- Analytical Methods, Vol. 9, Issue 34
Dorothy Crowfoot Hodgkin (1910–1994)
book, February 2016
- Loriaux, D. Lynn
- A Biographical History of Endocrinology
Plastid role in phytomelanin synthesis in Piptocarpha axillaris (Less.) Baker stems (Asteraceae, Vernonieae)
journal, March 2021
- Coutinho, Josiane Wolff; Rodrigues, Ana C.; Appezzato-da-Glória, Beatriz
- Protoplasma
Single‐cell dissection and microdroplet chemistry
journal, April 2001
- Outlaw, William H.; Zhang, Shuqiu
- Journal of Experimental Botany, Vol. 52, Issue 356
GMD@CSB.DB: The Golm Metabolome Database
text, January 2005
- Kopka, Joachim; Schauer, Nicolas; Krueger, Stephan
- ETH Zurich
Ambient Mass Spectrometry
book, January 2017
- Arndt, T.
- Lexikon der Medizinischen Laboratoriumsdiagnostik
Works referencing / citing this record:
Horizons of Systems Biocatalysis and Renaissance of Metabolite Synthesis
journal, May 2018
- Wohlgemuth, Roland
- Biotechnology Journal
Metabolomics reveals distinct methylation reaction in MeJA elicited Nigella sativa callus via UPLC–MS and chemometrics
journal, May 2015
- Farag, Mohamed A.; El Sayed, Abeer M.; El Banna, Ahmed
- Plant Cell, Tissue and Organ Culture (PCTOC), Vol. 122, Issue 2
Perspective: functional genomics towards new biotechnology in medicinal plants
journal, February 2018
- Yamazaki, Mami; Rai, Amit; Yoshimoto, Naoko
- Plant Biotechnology Reports, Vol. 12, Issue 2
Omics in Weed Science: A Perspective from Genomics, Transcriptomics, and Metabolomics Approaches
journal, August 2018
- Maroli, Amith S.; Gaines, Todd A.; Foley, Michael E.
- Weed Science, Vol. 66, Issue 6
NMR-based metabolomics strategies: plants, animals and humans
journal, January 2017
- Pontes, João Guilherme M.; Brasil, Antonio Jadson M.; Cruz, Guilherme C. F.
- Analytical Methods, Vol. 9, Issue 7
Integrated omics analysis of specialized metabolism in medicinal plants
journal, March 2017
- Rai, Amit; Saito, Kazuki; Yamazaki, Mami
- The Plant Journal, Vol. 90, Issue 4
Metabolomics 20 years on: what have we learned and what hurdles remain?
journal, June 2018
- Alseekh, Saleh; Fernie, Alisdair R.
- The Plant Journal, Vol. 94, Issue 6
Cannabis sativa: The Plant of the Thousand and One Molecules
journal, February 2016
- Andre, Christelle M.; Hausman, Jean-Francois; Guerriero, Gea
- Frontiers in Plant Science, Vol. 7
Generation of a Collision Cross Section Library for Multi-Dimensional Plant Metabolomics Using UHPLC-Trapped Ion Mobility-MS/MS
journal, December 2019
- Schroeder, Mark; Meyer, Sven W.; Heyman, Heino M.
- Metabolites, Vol. 10, Issue 1
Targeted Metabolomics of the Phenylpropanoid Pathway in Arabidopsis thaliana using Reversed Phase Liquid Chromatography Coupled with Tandem Mass Spectrometry : Measuring Lignin Precursors by LC-MS
journal, February 2017
- Jaini, Rohit; Wang, Peng; Dudareva, Natalia
- Phytochemical Analysis, Vol. 28, Issue 4
White cabbage (Brassica oleracea var. capitata f. alba): botanical, phytochemical and pharmacological overview
journal, January 2016
- Šamec, Dunja; Pavlović, Iva; Salopek-Sondi, Branka
- Phytochemistry Reviews, Vol. 16, Issue 1
Fortune telling: metabolic markers of plant performance
journal, September 2016
- Fernandez, Olivier; Urrutia, Maria; Bernillon, Stéphane
- Metabolomics, Vol. 12, Issue 10
Untargeted LC–MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase
journal, April 2019
- Chibli, Lucas A.; Rosa, Annylory L.; Nonato, Maria Cristina
- Metabolomics, Vol. 15, Issue 4
Phenotyping reproductive stage chilling and frost tolerance in wheat using targeted metabolome and lipidome profiling
journal, October 2019
- Cheong, Bo Eng; Ho, William Wing Ho; Biddulph, Ben
- Metabolomics, Vol. 15, Issue 11
Gossypol: phytoalexin of cotton
journal, January 2016
- Tian, Xiu; Ruan, Juxin; Huang, Jinquan
- Science China Life Sciences, Vol. 59, Issue 2
MetaOmGraph: a workbench for interactive exploratory data analysis of large expression datasets
journal, July 2019
- Singh, Urminder; Hur, Manhoi; Dorman, Karin
- Nucleic Acids Research
Functional Metabolomics—A Useful Tool to Characterize Stress-Induced Metabolome Alterations Opening New Avenues towards Tailoring Food Crop Quality
journal, August 2018
- Dawid, Corinna; Hille, Karina
- Agronomy, Vol. 8, Issue 8
Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants
journal, April 2018
- Zhu, Ming-Zhi; Chen, Gui-Lin; Wu, Jian-Lin
- Phytochemical Analysis, Vol. 29, Issue 4
Beyond the beaten path: improving natural products bioprospecting using an eco-evolutionary framework – the case of the octocorals
journal, June 2017
- Ledoux, Jean-Baptiste; Antunes, Agostinho
- Critical Reviews in Biotechnology, Vol. 38, Issue 2
MetaOmGraph: a workbench for interactive exploratory data analysis of large expression datasets
journal, January 2020
- Singh, Urminder; Hur, Manhoi; Dorman, Karin
- Nucleic Acids Research, Vol. 48, Issue 4
Metabolome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants
journal, September 2015
- Hagel, Jillian M.; Mandal, Rupasri; Han, Beomsoo
- BMC Plant Biology, Vol. 15, Issue 1
BioHackathon 2015: Semantics of data for life sciences and reproducible research
journal, January 2020
- Vos, Rutger A.; Katayama, Toshiaki; Mishima, Hiroyuki
- F1000Research, Vol. 9
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journal, November 2019
- Domingos, Olívia da S.; Alcântara, Bianca G. V.; Santos, Mário F. C.
- Molecules, Vol. 24, Issue 23
Root and leaf metabolite profiles analysis reveals the adaptive strategies to low potassium stress in barley
journal, September 2018
- Zeng, Jianbin; Quan, Xiaoyan; He, Xiaoyan
- BMC Plant Biology, Vol. 18, Issue 1
Using SSR-HRM to Identify Closely Related Species in Herbal Medicine Products: A Case Study on Licorice
journal, April 2018
- Li, Jingjian; Xiong, Chao; He, Xia
- Frontiers in Pharmacology, Vol. 9
Plant Metabolomics: An Indispensable System Biology Tool for Plant Science
journal, June 2016
- Hong, Jun; Yang, Litao; Zhang, Dabing
- International Journal of Molecular Sciences, Vol. 17, Issue 6
Mass spectrometry imaging for plant biology: a review
journal, October 2015
- Boughton, Berin A.; Thinagaran, Dinaiz; Sarabia, Daniel
- Phytochemistry Reviews, Vol. 15, Issue 3
Comparison of analytical techniques for the identification of bioactive compounds from natural products
journal, January 2016
- Cieśla, Łukasz; Moaddel, Ruin
- Natural Product Reports, Vol. 33, Issue 10
Draft genome assembly and annotation of Glycyrrhiza uralensis , a medicinal legume
journal, October 2016
- Mochida, Keiichi; Sakurai, Tetsuya; Seki, Hikaru
- The Plant Journal, Vol. 89, Issue 2
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journal, December 2016
- Dias, Daniel; Jones, Oliver; Beale, David
- Metabolites, Vol. 6, Issue 4
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journal, October 2015
- Boughton, Berin A.; Thinagaran, Dinaiz; Sarabia, Daniel
- Phytochemistry Reviews, Vol. 15, Issue 3
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journal, September 2016
- Fernandez, Olivier; Urrutia, Maria; Bernillon, Stéphane
- Metabolomics, Vol. 12, Issue 10
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journal, October 2019
- Cheong, Bo Eng; Ho, William Wing Ho; Biddulph, Ben
- Metabolomics, Vol. 15, Issue 11
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journal, February 2016
- Spalding, Jonathan L.; Cho, Kevin; Mahieu, Nathaniel G.
- Analytical Chemistry, Vol. 88, Issue 5
Metabolomics reveals biotic and abiotic elicitor effects on the soft coral Sarcophyton ehrenbergi terpenoid content
journal, April 2017
- Farag, Mohamed A.; Al-Mahdy, Dalia A.; Meyer, Achim
- Scientific Reports, Vol. 7, Issue 1
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journal, January 2020
- Singh, Urminder; Hur, Manhoi; Dorman, Karin
- Nucleic Acids Research, Vol. 48, Issue 4
Dark period transcriptomic and metabolic profiling of two diverse Eutrema salsugineum accessions
journal, July 2017
- Yin, Jie; Gosney, Michael J.; Dilkes, Brian P.
- Plant Direct
Free Radical Scavenging Activity and Comparative Metabolic Profiling of In Vitro Cultured and Field Grown Withania somnifera Roots
journal, April 2015
- Senthil, Kalaiselvi; Thirugnanasambantham, Pankajavalli; Oh, Taek Joo
- PLOS ONE, Vol. 10, Issue 4
Livestock metabolomics and the livestock metabolome: A systematic review
journal, May 2017
- Goldansaz, Seyed Ali; Guo, An Chi; Sajed, Tanvir
- PLOS ONE, Vol. 12, Issue 5
Encoding information in synthetic metabolomes
journal, July 2019
- Kennedy, Eamonn; Arcadia, Christopher E.; Geiser, Joseph
- PLOS ONE, Vol. 14, Issue 7
13C Metabolomics: NMR and IROA for Unknown Identification
journal, June 2016
- S. Clendinen, Chaevien; S. Stupp, Gregory; Wang, Bing
- Current Metabolomics, Vol. 4, Issue 2
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journal, April 2018
- Li, Jingjian; Xiong, Chao; He, Xia
- Frontiers in Pharmacology, Vol. 9
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journal, February 2016
- Andre, Christelle M.; Hausman, Jean-Francois; Guerriero, Gea
- Frontiers in Plant Science, Vol. 7
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journal, February 2016
- Dong, Yonghui; Li, Bin; Malitsky, Sergey
- Frontiers in Plant Science, Vol. 7
Distinguishing Six Edible Berries Based on Metabolic Pathway and Bioactivity Correlations by Non-targeted Metabolite Profiling
journal, October 2018
- Suh, Dong Ho; Jung, Eun Sung; Lee, Gyu Min
- Frontiers in Plant Science, Vol. 9
Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet
journal, November 2018
- Li, Shuangdong; Dong, Xuekui; Fan, Guangyu
- Frontiers in Plant Science, Vol. 9
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journal, June 2016
- Hong, Jun; Yang, Litao; Zhang, Dabing
- International Journal of Molecular Sciences, Vol. 17, Issue 6
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journal, December 2019
- Schroeder, Mark; Meyer, Sven W.; Heyman, Heino M.
- Metabolites, Vol. 10, Issue 1
Metabolite and Phytohormone Profiling Illustrates Metabolic Reprogramming as an Escape Strategy of Deepwater Rice during Partially Submerged Stress
journal, February 2020
- Fukushima, Atsushi; Kuroha, Takeshi; Nagai, Keisuke
- Metabolites, Vol. 10, Issue 2
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journal, September 2018
- Lei, Zhentian; Kranawetter, Clayton; Sumner, Barbara
- Metabolites, Vol. 8, Issue 4
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journal, November 2019
- Domingos, Olívia da S.; Alcântara, Bianca G. V.; Santos, Mário F. C.
- Molecules, Vol. 24, Issue 23