Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
|
journal
|
October 2012 |
A Substantial Transmission Bottleneck among Newly and Recently HIV‐1–Infected Injection Drug Users in St Petersburg, Russia
- Masharsky, Alexey E.; Dukhovlinova, Elena N.; Verevochkin, Sergei V.
-
The Journal of Infectious Diseases, Vol. 201, Issue 11
https://doi.org/10.1086/652702
|
journal
|
June 2010 |
Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine
|
journal
|
November 2013 |
Structure of a human monoclonal antibody Fab fragment against gp41 of human immunodeficiency virus type 1.
|
journal
|
August 1992 |
Specificity and 6-Month Durability of Immune Responses Induced by DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-Like Particles
|
journal
|
January 2014 |
Conserved and Exposed Epitopes on Intact, Native, Primary Human Immunodeficiency Virus Type 1 Virions of Group M
|
journal
|
August 2000 |
Nonneutralizing Antibodies Are Able To Inhibit Human Immunodeficiency Virus Type 1 Replication in Macrophages and Immature Dendritic Cells
|
journal
|
May 2006 |
Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial
|
journal
|
September 2013 |
Structural characterization of a fusion glycoprotein from a retrovirus that undergoes a hybrid 2-step entry mechanism
|
journal
|
December 2013 |
Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial
|
journal
|
April 2012 |
Improving Defences at the Portal of HIV Entry: Mucosal and Innate Immunity
|
journal
|
April 2008 |
Recombinant soluble human Fcγ receptor I with picomolar affinity for immunoglobulin G
|
journal
|
December 2005 |
Functional, Non-Clonal IgMa-Restricted B Cell Receptor Interactions with the HIV-1 Envelope gp41 Membrane Proximal External Region
|
journal
|
October 2009 |
The role of dynamic conformational ensembles in biomolecular recognition
|
journal
|
October 2009 |
N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus
|
journal
|
March 2008 |
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
|
journal
|
November 2007 |
Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding
|
journal
|
December 2012 |
A Recombinant Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Complex Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits Is an Antigenic Mimic of the Trimeric Virion-Associated Structure
|
journal
|
January 2000 |
Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L
|
journal
|
November 2009 |
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
|
journal
|
August 2014 |
Wide Variation in the Multiplicity of HIV-1 Infection among Injection Drug Users
|
journal
|
April 2010 |
High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies
|
journal
|
June 2009 |
Studies of the "Chain Reversal Regions" of the Avian Sarcoma/Leukosis Virus (ASLV) and Ebolavirus Fusion Proteins: Analogous Residues Are Important, and a His Residue Unique to EnvA Affects the pH Dependence of ASLV Entry
|
journal
|
March 2010 |
Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG
|
journal
|
May 2013 |
Neutralizing as well as non-neutralizing polyclonal immunoglobulin (Ig)G from infected patients capture HIV-1 via antibodies directed against the principal immunodominant domain of gp41
|
journal
|
March 2005 |
The Structure of an Antitumor CH2-domain-deleted Humanized Antibody
|
journal
|
May 2005 |
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
|
journal
|
May 2008 |
GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium
|
journal
|
March 2010 |
Crystal Structure of the Ebola Virus Membrane Fusion Subunit, GP2, from the Envelope Glycoprotein Ectodomain
|
journal
|
November 1998 |
Quantitating the Multiplicity of Infection with Human Immunodeficiency Virus Type 1 Subtype C Reveals a Non-Poisson Distribution of Transmitted Variants
|
journal
|
February 2009 |
Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand
|
journal
|
December 2009 |
Interaction between a Fab fragment against gp41 of human immunodeficiency virus 1 and its peptide epitope: characterization using a peptide epitope library and molecular modeling
|
journal
|
January 1995 |
Three-dimensional solution structure of the 44kDa ectodomain of SIV gp41
|
journal
|
August 1998 |
High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men
|
journal
|
May 2010 |
Dynamic Antibody Specificities and Virion Concentrations in Circulating Immune Complexes in Acute to Chronic HIV-1 Infection
|
journal
|
August 2011 |
Nature of Nonfunctional Envelope Proteins on the Surface of Human Immunodeficiency Virus Type 1
|
journal
|
February 2006 |
Extensive complement-dependent enhancement of HIV-1 by autologous non-neutralising antibodies at early stages of infection
|
journal
|
January 2011 |
Live Simian Immunodeficiency Virus Vaccine Correlate of Protection: Local Antibody Production and Concentration on the Path of Virus Entry
|
journal
|
August 2014 |
The Role of Antibody Polyspecificity and Lipid Reactivity in Binding of Broadly Neutralizing Anti-HIV-1 Envelope Human Monoclonal Antibodies 2F5 and 4E10 to Glycoprotein 41 Membrane Proximal Envelope Epitopes
|
journal
|
March 2007 |
Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies
|
journal
|
June 2005 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
|
journal
|
January 2010 |
Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia
|
journal
|
October 2008 |
Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells
|
journal
|
August 2008 |
Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
|
journal
|
March 1987 |
Fc receptor but not complement binding is important in antibody protection against HIV
|
journal
|
September 2007 |
Estimating time since infection in early homogeneous HIV-1 samples using a poisson model
|
journal
|
October 2010 |
Human Immunodeficiency Virus Type 1 Spinoculation Enhances Infection through Virus Binding
|
journal
|
November 2000 |
Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC
|
journal
|
December 2010 |
Modeling sequence evolution in acute HIV-1 infection
|
journal
|
November 2009 |
The HIV-1 gp120 CD4-Bound Conformation Is Preferentially Targeted by Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Sera from HIV-1-Infected Individuals
|
journal
|
October 2014 |
Neutralizing Antibodies and Control of HIV: Moves and Countermoves
|
journal
|
December 2011 |
Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated
|
journal
|
October 2011 |
Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies
|
journal
|
September 2012 |
Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce β-chemokines
|
journal
|
April 2010 |
Heterogeneity of Envelope Molecules Expressed on Primary Human Immunodeficiency Virus Type 1 Particles as Probed by the Binding of Neutralizing and Nonneutralizing Antibodies
|
journal
|
January 2003 |
Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection
|
journal
|
August 2014 |
[20] Processing of X-ray diffraction data collected in oscillation mode
|
book
|
January 1997 |
Role of complement and Fc receptors in the pathogenesis of HIV-1 infection
|
journal
|
January 1997 |
Nonneutralizing Antibodies to the CD4-Binding Site on the gp120 Subunit of Human Immunodeficiency Virus Type 1 Do Not Interfere with the Activity of a Neutralizing Antibody against the Same Site
|
journal
|
January 2003 |
Functional Analysis of the Disulfide-Bonded Loop/Chain Reversal Region of Human Immunodeficiency Virus Type 1 gp41 Reveals a Critical Role in gp120-gp41 Association
|
journal
|
July 2001 |
In Vivo Efficacy of Anti-Glycoprotein 41, But Not Anti-Glycoprotein 120, Immunotoxins in a Mouse Model of HIV Infection
|
journal
|
February 2003 |
Induction of Immunity to Human Immunodeficiency Virus Type-1 by Vaccination
|
journal
|
October 2010 |
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
|
journal
|
October 2014 |
The Human Low Affinity Fcγ Receptors IIa, IIb, and III Bind IgG with Fast Kinetics and Distinct Thermodynamic Properties
|
journal
|
September 2001 |
Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals
|
journal
|
August 2011 |
Model for the structure of the HIV gp41 ectodomain: insight into the intermolecular interactions of the gp41 loop
|
journal
|
May 2001 |
Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution
|
journal
|
March 2010 |
Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men
|
journal
|
January 2008 |
Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins
|
journal
|
April 1999 |
Advancing Toward HIV-1 Vaccine Efficacy through the Intersections of Immune Correlates
|
journal
|
December 2013 |
Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1
|
journal
|
January 2009 |
Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard
|
journal
|
December 2007 |
HIV-1 Vaccine-Induced C1 and V2 Env-Specific Antibodies Synergize for Increased Antiviral Activities
|
journal
|
May 2014 |
Characterization of a Simian Human Immunodeficiency Virus Encoding the Envelope Gene from the CCR5-Tropic HIV-1 Ba-L
|
journal
|
January 2003 |
HIV-1 neutralizing antibodies: understanding nature's pathways
|
journal
|
June 2013 |
Structural and Immunological Characterisation of Heteroclitic Peptide Analogues Corresponding to the 600–612 Region of the HIV Envelope gp41 Glycoprotein
|
journal
|
October 2002 |
Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity
|
journal
|
December 2013 |
A New Clustering of Antibody CDR Loop Conformations
|
journal
|
February 2011 |
Delineation of multiple subpopulations of natural killer cells in rhesus macaques
|
journal
|
June 2005 |
Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2
|
journal
|
January 2013 |
Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage
|
journal
|
February 2005 |
Neutralizing IgG at the Portal of Infection Mediates Protection against Vaginal Simian/Human Immunodeficiency Virus Challenge
|
journal
|
August 2013 |
Strategies for eliciting HIV-1 inhibitory antibodies
|
journal
|
January 2010 |
Structural evidence for induced fit as a mechanism for antibody-antigen recognition
|
journal
|
February 1992 |
Vaccine-Induced Env V1-V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination
|
journal
|
March 2014 |
Flexibility and molecular recognition in the immune system
|
journal
|
December 2002 |
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1
|
journal
|
May 2009 |
Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques
|
journal
|
April 2013 |
Retrovirus envelope domain at 1.7 Å resolution
|
journal
|
May 1996 |
HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life
|
journal
|
January 2013 |
A Nonfucosylated Variant of the anti-HIV-1 Monoclonal Antibody b12 Has Enhanced Fc RIIIa-Mediated Antiviral Activity In Vitro but Does Not Improve Protection against Mucosal SHIV Challenge in Macaques
|
journal
|
March 2012 |
Is developing an HIV-1 vaccine possible?
|
journal
|
January 2010 |
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody
|
journal
|
June 2011 |
Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges
|
journal
|
February 2011 |
Detecting hypermutations in viral sequences with an emphasis on G -> A hypermutation
|
journal
|
April 2000 |
Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials
|
journal
|
May 2012 |
Ex vivo culture of human colorectal tissue for the evaluation of candidate microbicides
|
journal
|
January 2006 |
Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions
|
journal
|
March 2010 |
Structure validation by Cα geometry: ϕ,ψ and Cβ deviation
|
journal
|
January 2003 |
Solvent content of protein crystals
|
journal
|
April 1968 |
Human Immunodeficiency Virus Type 1 gp41 Antibodies That Mask Membrane Proximal Region Epitopes: Antibody Binding Kinetics, Induction, and Potential for Regulation in Acute Infection
|
journal
|
October 2007 |
An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum
|
journal
|
May 2011 |
In-Solution Virus Capture Assay Helps Deconstruct Heterogeneous Antibody Recognition of Human Immunodeficiency Virus Type 1
|
journal
|
January 2010 |
High Resolution Mapping of the Binding Site on Human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and Design of IgG1 Variants with Improved Binding to the FcγR
|
journal
|
November 2000 |
Functional Implications of the Human T-Lymphotropic Virus Type 1 Transmembrane Glycoprotein Helical Hairpin Structure
|
journal
|
July 2000 |
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin
|
journal
|
August 2011 |
Mapping the anatomy of the immunodominant domain of the human immunodeficiency virus gp41 transmembrane protein: peptide conformation analysis using monoclonal antibodies and proton nuclear magnetic resonance spectroscopy.
|
journal
|
January 1991 |
Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein.
|
journal
|
January 1993 |
Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding.
|
journal
|
January 1993 |
Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding.
|
journal
|
January 1995 |
Protein-peptide interactions
|
journal
|
February 1995 |
Infectious Virion Capture by HIV-1 gp120-Specific IgG from RV144 Vaccinees
|
journal
|
May 2013 |