Simplified one-pot synthesis of [.sup.18F]SFB for radiolabeling
Patent
·
OSTI ID:1207285
A non-aqueous single pot synthesis of [.sup.18F]SFB is set forth. The [.sup.18F]SFB produced with this method is then used, for example, to label a peptide or an engineered antibody fragment (diabody) targeting human epidermal growth factor receptor 2 (HER2) as representative examples of labeled compounds for use as an injectable composition to locate abnormal tissue, specifically tumors within an animal or human using a PET scan.
- Research Organization:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FG02-06ER64249
- Assignee:
- The Regents Of The University Of California (Oakland, CA)
- Patent Number(s):
- 9,096,647
- Application Number:
- 13/924,397
- OSTI ID:
- 1207285
- Resource Relation:
- Patent File Date: 2013 Jun 21
- Country of Publication:
- United States
- Language:
- English
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