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Title: Variants of beta-glucosidase

Patent ·
OSTI ID:1193382

The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

Research Organization:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC36-98GO10337
Assignee:
Novozymes, Inc. (Davis, CA)
Patent Number(s):
9,080,165
Application Number:
14/507,539
OSTI ID:
1193382
Resource Relation:
Patent File Date: 2014 Oct 06
Country of Publication:
United States
Language:
English

References (4)

Cellulase variants and detergent compositions containing cellulase variants patent August 1998
Endoglucanases patent December 1999
Genetic constructs and genetically modified microbes for enhanced production of beta-glucosidase patent January 2000
Cloning and sequencing of the cDNA encoding β-glucosidase 1 from Aspergillus aculeatus journal September 1996

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