Multi-modality nanoparticles having optically responsive shape

Patent · Tue May 19 00:00:00 EDT 2015

OSTI ID:1179791

Chen, Fanqing; Bouchard, Louis-Serge

In certain embodiments novel nanoparticles (nanowontons) are provided that are suitable for multimodal imaging and/or therapy. In one embodiment, the nanoparticles include a first biocompatible (e.g., gold) layer, an inner core layer (e.g., a non-biocompatible material), and a biocompatible (e.g., gold) layer. The first gold layer includes a concave surface that forms a first outer surface of the layered nanoparticle. The second gold layer includes a convex surface that forms a second outer surface of the layered nanoparticle. The first and second gold layers encapsulate the inner core material layer. Methods of fabricating such nanoparticles are also provided.

• Research Organization: Argonne National Laboratory (ANL), Argonne, IL (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC02-05CH11231
• Assignee: The Regents of the University of California (Oakland, CA)
• Patent Number(s): 9,037,214
• Application Number: 13/202,976
• OSTI ID: 1179791
• Resource Relation: Patent File Date: 2010 Feb 23
• Country of Publication: United States
• Language: English

Related Subjects

77 NANOSCIENCE AND NANOTECHNOLOGY
60 APPLIED LIFE SCIENCES
36 MATERIALS SCIENCE